日本内科学会

1988.4

日本消化器病学会

1988.4

Background factors of idiopathic peptic ulcers and optimal treatment methods: a multicenter retrospective Japanese study. Reviewed

Nakajima N, Takeuchi T, Hokari R, Narimatsu K, Iijima K, Koizumi S, Kasugai K, Ebi M, Nagahara A, Takeda T, Tomita T, Shinzaki S, Mizukami K, Murakami K, Yagi N, Mukai R, Okumura T, Tanabe H, Tanaka K, Iwamoto J, Irisawa A, Fukushi K, Kataoka H, Nishie H, Fujiwara Y, Otani K, Handa O, Maruyama Y, Uraoka T, Hosaka H, Furuta T, Takagi T, Nakamura M, Nyumura Y, Hakoda A, Sugawara N, Iwatubo T, Ota K, Kawaguchi S, Higuchi K, Nishikawa H.

J Clin Biochem Nutr.   2024

Probiotic-derived ferrichrome induces DDIT3-mediated antitumor effects in esophageal cancer cells. Reviewed

Kunogi T, Konishi H, Sakatani A, Moriichi K, Yamamura C, Yamamoto K, Kashima S, Ando K, Ueno N, Tanaka H, Okumura T, Fujiya M

Heliyon   2024

New gel immersion endoscopic ultrasonography technique for accurate periampullary evaluation. Reviewed

Sato H, Kawabata H, Iwamoto H, Okada T, Fujibayashi S, Takahashi K, Kitano Y, Goto T, Mizukami Y, Okumura T, Fujiya M

Surg Endosc   2024

Liquid Biopsy for Pancreatic Cancer by Serum Extracellular Vesicle-Encapsulated Long Noncoding RNA HEVEPA. Reviewed

Takahashi K, Inuzuka T, Shimizu Y, Sawamoto K, Taniue K, Ono Y, Asai F, Koyama K, Sato H, Kawabata H, Iwamoto H, Yamakita K, Kitano Y, Teramoto T, Fujiya M, Fujii S, Mizukami Y, Okumura T

Pancreas   2024

Genomic insights into familial adenomatous polyposis: unraveling a rare case with whole APC gene deletion and intellectual disability. Reviewed

Tanabe H, Ijiri M, Takahashi K, Sasagawa H, Kamanaka T, Kuroda S, Sato H, Sarashina T, Mizukami Y, Makita Y, Okumura T.

Hum Genome Var   2024

Monitoring mutant KRAS in plasma cell-free DNA can predict disease progression in a patient with multiple myeloma: A case report. Reviewed

Yamamoto M, Shindo M, Funayama T, Sumi C, Saito T, Toki Y, Hatayama M, Ono Y, Sato K, Mizukami Y, Okumura T.

Clin Chim Acta   2023

Concomitant pharmacologic medications influence the clinical outcomes of granulocyte and monocyte adsorptive apheresis in patients with ulcerative colitis: A multicenter retrospective cohort study. Reviewed

Ueno N, Sugiyama Y, Kobayashi Y, Murakami Y, Iwama T, Sasaki T, Kunogi T, Sakatani A, Takahashi K, Tanaka K, Serikawa S, Ando K, Kashima S, Muto M, Inaba Y, Moriichi K, Tanabe H, Okumura T, Fujiya M

J Clin Apher   2023

Centrally administered GLP-1 analogue improves intestinal barrier function through the brain orexin and the vagal pathway in rats. Reviewed

Funayama T, Nozu T, Ishioh M, Igarashi S, Sumi C, Saito T, Toki Y, Hatayama M, Yamamoto M, Shindo M, Tanabe H, Okumura T.

Brain Res   2023

Ghrelin prevents lethality in a rat endotoxemic model through central effects on the vagal pathway and adenosine A2B signaling : Brain ghrelin and anti-septic action. Reviewed

Igarashi S, Nozu T, Ishioh M, Funayama T, Sumi C, Saito T, Toki Y, Hatayama M, Yamamoto M, Shindo M, Tanabe H, Okumura T.

J Physiol Biochem   2023

The safety of vedolizumab in a patient with Crohn's disease who developed anti-TNF-alpha agent associated latent tuberculosis infection reactivation: A case report. Reviewed

Sugiyama Y, Ueno N, Tachibana S, Kobayashi Y, Murakami Y

Medicine   2023

Imeglimin prevents visceral hypersensitivity and colonic hyperpermeability in irritable bowel syndrome rat model. Reviewed

Nozu T, Miyagishi S, Ishioh M, Takakusaki K, Okumura T.

J Pharmacol Sci.   2023

Phlorizin attenuates postoperative gastric ileus in rats. Reviewed

Nozu T, Miyagishi S, Ishioh M, Takakusaki K, Okumura T.

Neurogastroenterol Motil   2023

A Case of Adult-onset Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis Syndrome Responsive to Colchicine. Reviewed

Nozu T, Ohhira M, Ishioh M, Okumura T.

Intern Med   2023

The effect of heat-killed Lactobacillus brevis SBL88 on improving selective hepatic insulin resistance in non-alcoholic fatty liver disease mice without altering the gut microbiota. Reviewed

Hayashi H, Sawada K, Tanaka H, Muro K, Hasebe T, Nakajima S, Okumura T, Fujiya M

J Gastrol Hepatol   2023

Contrast-enhanced Ultrasonography Features for Diagnosing Pseudoprogression of Hepatocellular Carcinoma with Immunotherapy: A Case Report of the Response after Pseudoprogression. Reviewed

Otake S, Ota Y, Aso K, Okada M, Hayashi H, Hasebe T, Nakajima S, Sawada K, Fujiya M, Okumura T.

Intern Med   2023

Brain Neuropeptides, Neuroinflammation, and Irritable Bowel Syndrome. Invited Reviewed

Ishioh M, Nozu T, Okumura T.

Digestion   2023

Local recurrence after successful endoscopic submucosal dissection for rectal mucinous mucosal adenocarcinoma: A case report. Reviewed

Murakami Y, Tanabe H, Ono Y, Sugiyama Y, Kobayashi Y, Kunogi T, Sasaki T, Takahashi K, Ando K, Ueno N, Kashima S, Yuzawa S, Moriichi K, Mizukami Y, Fujiya M, Okumura T.

World J Gastrointest Oncol   2023

Prostaglandin I2 suppresses the development of gut-brain axis disorder in irritable bowel syndrome in rats Reviewed

Kumei S, Ishioh M, Nozu T, Okumura T

Biochim Biophys Acta Gen Subj.   2023

Testis-specific hnRNP is expressed in colorectal cancer cells and accelerates cell growth mediating ZDHHC11 mRNA stabilization. Reviewed

Murakami Y, Konishi H, Fujiya M, Takahashi K, Ando K, Ueno N, Kashima S, Moriichi K, Tanabe H, Okumura T.

Cancer Med   2022

Prognostic factors to predict the survival in patients with advanced gastric cancer who receive later-line nivolumab monotherapy-The Asahikawa Gastric Cancer Cohort Study (AGCC). Reviewed

Tanaka K, Tanabe H, Sato H, Ishikawa C, Goto M, Yanagida N, Akabane H, Yokohama S, Hasegawa K, Kitano Y, Sugiyama Y, Uehara K, Kobayashi Y, Murakami Y, Kunogi T, Sasaki T, Takahashi K, Ando K, Ueno N, Kashima S, Moriichi K, Sato K, Yuzawa S, Tanino M, Taruiishi M, Sumi Y, Mizukami Y, Fujiya M, Okumura T.

Cancer Med   2022

Mutant GNAS limits tumor aggressiveness in established pancreatic cancer via antagonizing the KRAS-pathway. Reviewed

Kawabata H, Ono Y, Tamamura N, Oyama K, Ueda J, Sato H, Takahashi K, Taniue K, Okada T, Fujibayashi S, Hayashi A, Goto T, Enomoto K, Konishi H, Fujiya M, Miyakawa K, Tanino M, Nishikawa Y, Koga D, Watanabe T, Maeda C, Karasaki H, Liss AS, Mizukami Y, Okumura T

J Gastroenterol   2022

Artificial intelligence-assisted detection of colorectal polyps in Lynch syndrome Reviewed

Tanabe H, Moriichi K, Mizukami Y, Fujiya M, Okumura

Gastrointestinal Endosc   2022

Pathophysiological Commonality Between Irritable Bowel Syndrome and Metabolic Syndrome: Role of Corticotropin-releasing Factor-Toll-like Receptor 4-Proinflammatory Cytokine Signaling. Reviewed

Nozu T, Okumura T

J Neurogastroenterol Mobil   2022

Carbazochrome sodium sulfonate is not effective for prevention of post-gastric endoscopic submucosal dissection bleeding: A retrospective study. Reviewed

Takahashi K, Sasaki T, Ueno N, Uehara K, Kobayashi Y, Sugiyama Y, Murakami Y, Kunogi T, Ando K, Kashima S, Moriichi K, Tanabe H, Okumura T, Fujiya

Surg Ends   2022

Late-onset posttransplant Epstein-Barr virusrelated lymphoproliferative disease after cord blood transplantation for chronic active Epstein Barr virus infection: A case report Reviewed

Yamamoto M, Shindo M, Funayama T, Sumi C, Saito T, Toki Y, Hatayama M, Imadome KI, Mizukami Y, Okumura T.

Medicine (Baltimore)   2022

Gastro-colic Fistula-associated Hypersplenism Causes Pancytopenia in a Patient with Crohn's Disease: A Case Report. Reviewed

Saito S, Ueno N, Kamikokura Y, Sugiyama Y, Kobayashi Y, Murakami Y, Kunogi T, Sasaki T, Takahashi K, Ando K, Kashima S, Moriichi K, Tanabe H, Tanino M, Okumura T, Fujiya M.

Intern Med   2022

Nasal breathing is superior to oral breathing in performing and undergoing transnasal endoscopy: a randomized trial. Reviewed

Takahashi K, Yuki M, Takahiro S, Ueno N, Tachibana S, Ikeda J, Ishigaki K, Horiuchi M, Yoshida M, Uehara K, Kobayashi Y, Yuya S, Kunogi T, Shimoda M, Ando K, Muto M, Kashima S, Moriichi K, Tanabe H, Yanagawa N, Harada K, Teramoto T, Okumura T, Fujiya M

Endoscopy   2022

Oxytocin acts centrally in the brain to improve leaky gut through the vagus nerve and a cannabinoid signaling in rats. Reviewed

Okumura T, Nozu T, Ishioh M, Igarashi S, Funayama T, Kumei S, Ohhira M

Physiol Behav   2022

A patient with familial Mediterranean fever mimicking diarrhea-dominant irritable bowel syndrome who successfully responded to treatment with colchicine: a case report. Reviewed

Kumei S, Ishioh M, Murakami Y, Ando K, Nozu T, Okumura T.

J Med Case Rep   2022

Severe immune checkpoint inhibitor-associated gastritis: A case series and literature review. Reviewed

Sugiyama Y, Tanabe H, Matsuya T, Kobayashi Y, Murakami Y, Sasaki T, Kunogi T, Takahashi K, Ando K, Ueno N, Kashima S, Moriichi K, Tanino M, Mizukami Y, Fujiya M, Okumura T.

Ends Int Open   2022

Epipericardial Fat Necrosis: A Retrospective Analysis in Japan Reviewed

Kumei S, Ishitoya S, Oya A, Ohhira M, Ishioh M, Okumura T

Intern Med   2022

Activation of basal forebrain cholinergic neurons improves colonic hyperpermeability through the vagus nerve and adenosine A2B receptors in rats. Reviewed

Ishioh M, Nozu T, Miyagishi S, Igarashi S, Funayama T, Ohhira M, Okumura T.

Biochem Pharmacol   2022

Contrast-enhanced ultrasonography for the diagnosis of spontaneous necrosis of hepatocellular carcinoma: A report of 2 cases Reviewed

Ota Y, Aso K, Otake S, Okada M, Shukuda K, Sawada K, Yokoo H, Tanino M, Fujiya M, Okumura T.

Radiol Case Rep   2022

Long Non-Coding RNAs in Epithelial-Mesenchymal Transition of Pancreatic Cancer Reviewed

Takahashi K, Taniue K, Ono Y, Fujiya M, Mizukami Y, Okumura T.

Front Mol Biosci.   2021

A stealth antigen SPESP1, which is an epigenetically silenced in tumors, is a suitable target for cancer immunotherapy. Reviewed

Kosaka A, Yajima Y, Hatayama M, Ikuta K, Sasaki T, Hirai N, Yasuda S, Nagata M, Hayashi R, Harabuchi S, Ohara K, Ohara M, Kumai T, Ishibashi K, Hirata-Nozaki Y, Nagato T, Oikawa K, Harabuchi Y, Esteban C, Okumura T, Ohsaki Y, Kobayashi H, Ohkuri T.

Cancer Sci   2021

EMA401, an angiotensin II type 2 receptor antagonist blocks visceral hypersensitivity and colonic hyperpermeability in rat model of irritable bowel syndrome. Reviewed

Nozu T, Miyagishi S, Nozu R, Ishioh M, Takakusaki K, Okumura T.

J Pharmacol Sci   2021

Safety and efficacy of cold snare polypectomy for small colorectal polyps: A prospective randomized control trial and one-year follow-up study. Reviewed

Ito T, Takahashi K, Tanabe H, Sato K, Goto M, Sato T, Tanaka K, Utsumi T, Fujinaga A, Kawamoto T, Yanagawa N, Moriichi K, Fujiya M, Okumura T

Medicine (Baltimore)   2021

Centrally administered butyrate improves gut barrier function, visceral sensation and septic lethality in rats Reviewed

Okumura T, Nozu T, Ishioh M, Igarashi S, Kumei S, Ohhira M

J Pharmacol Sci   2021

Case Report: A Rare Case of Esophagogastric Junctional Squamous Cell Carcinoma After the Successful Treatment of Neuroendocrine Carcinoma: Clonal Tumor Evolution Revealed by Genetic Analysis. Reviewed

Sato H, Saito T, Horii H, Kajiura M, Kikuchi N, Takada N, Taguchi K, Yoshida M, Hasegawa M, Taguchi H, Yoshida Y, Ando K, Fujiya M, Omori Y, Hank T, Liss AS, Gala MK, Makita Y, Ono Y, Mizukami Y, Okumura T.

Front Genet   2021

Successful Treatment of Advanced Gastric Cancer with Brain Metastases through an Abscopal Effect by Radiation and Immune Checkpoint Inhibitor Therapy. Invited Reviewed

Muto M, Nakata H, Ishigaki K, Tachibana S, Yoshida M, Muto M, Yanagawa N, Okumura T

J Gastric Cancer   2021

Centrally administered butyrate improves gut barrier function, visceral sensation and septic lethality in rats. Reviewed

Okumura T, Nozu T, Ishioh M, Igarashi S, Kumei S, Ohhira M.

J Pharmacol Sci   2021

Polyphosphate, Derived from Lactobacillus brevis, Modulates the Intestinal Microbiome and Attenuates Acute Pancreatitis. Reviewed

Takauji S, Konishi H, Fujiya M, Ueno N, Tanaka H, Sato H, Isozaki S, Kashima S, Moriichi K, Mizukami Y, Okumura T.

Dig Dis Sci   2021

Cardiac Metastasis Caused Fatal Ventricular Arrhythmia in a Patient with a Rectal Neuroendocrine Tumor. Reviewed

Ando K, Fujiya M, Yoshida M, Kobayashi Y, Sugiyama Y, Murakami Y, Iwama T, Sato H, Sasaki T, Kunogi T, Takahashi K, Ueno N, Kashima S, Moriichi K, Tanabe H, Okumura T.

Intern Med   2021

Rare case of fecal impaction caused by a fecalit Reviewed

Tanabe H, Tanaka K, Goto M, Sato T, Sato K, Fujiya M, Okumura T.

World J Clin Cases   2021

Central regulatory mechanisms of visceral sensation in response to colonic distension with special reference to brain orexin. Reviewed

Okumura T, Ishioh M, Nozu T

Neuropeptides   2021

Prognostic significance of skeletal muscle decrease in unresectable pancreatic cancer: Survival analysis using the Weibull exponential distribution model. Reviewed

Sato H, Goto T, Hayashi A, Kawabata H, Okada T, Takauji S, Sasajima J, Enomoto K, Fujiya M, Oyama K, Ono Y, Sugitani A, Mizukami Y, Okumura T.

Pancreatology   2021

Clinicopathological characteristics of Epstein-Barr virus and microsatellite instability subtypes of early gastric neoplasms classified by the Japanese and the World Health Organization criteria. Reviewed

Tanabe H, Mizukami Y, Takei H, Tamamura N, Omura Y, Kobayashi Y, Murakami Y, Kunogi T, Sasaki T, Takahashi K, Ando K, Ueno N, Kashima S, Yuzawa S, Hasegawa K, Sumi Y, Tanino M, Fujiya M, Okumura T.

J Pathol Clin Res   2021

Activation of central adenosine A2B receptors mediate brain ghrelin-induced improvement of intestinal barrier function through the vagus nerve in rats Reviewed

Ishioh M, Nozu T, Igarashi S, Tanabe H, Kumei S, Ohhira M, Takakusaki K, Okumura T

Exp Neurol   2021

Long-term Observation of Gastric Adenocarcinoma of Fundic Gland Mucosa Type before and after Helicobacter pylori Eradication: a Case Report. Reviewed

Takahashi K, Ueno N, Sasaki T, Kobayashi Y, Sugiyama Y, Murakami Y, Kunogi T, Ando K, Kashima S, Moriichi K, Tanabe H, Kamikokura Y, Yuzawa S, Tanino M, Okumura T, Fujiya M.

J Gastric Cancer   2021

Probiotic-Derived Polyphosphate Accelerates Intestinal Epithelia Wound Healing through Inducing Platelet-Derived Mediators. Invited Reviewed

Isozaki S, Konishi H, Fujiya M, Tanaka H, Murakami Y, Kashima S, Ando K, Ueno N, Moriichi K, Okumura T.

Mediators Inflamm   2021

Acquired hemophilia A associated with Epstein-Barr-virus-associated T/natural kill Reviewed

Yamamoto M, Shindo M, Sumi C, Igarashi S, Saito T, Tsukada N, Toki Y, Hatayama M, Inamura J, Sato K, Mizukami Y, Torimoto Y, Okumura T.

Medicine (Baltimore).   2021

Evidence-based clinical practice guidelines for irritable bowel syndrome 2020. Reviewed

Fukudo S, Okumura T, Inamori M, Okuyama Y, Kanazawa M, Kamiya T, Sato K, Shiotani A, Naito Y, Fujikawa Y, Hokari R, Masaoka T, Fujimoto K, Kaneko H, To

J Gastroenterol   2021

The Optimal Dose of Tacrolimus in Combination Therapy with an Anti-TNFα Antibody in a Mouse Colitis Model. Reviewed

Murakami Y, Fujiya M, Konishi H, Isozaki S, Sugiyama Y, Kobayashi Y, Sasaki T, Kunogi T, Takahashi K, Ando K, Ueno N, Kashima S, Moriichi K, Tanabe H, Okumura T

Biol Pharm Bull   2021

Phlorizin attenuates visceral hypersensitivity and colonic hyperpermeability in a rat model of irritable bowel syndrome. Reviewed

Nozu T, Miyagishi S, Ishioh M, Takakusaki K, Okumura T.

Biomed Pharmacother.   2021

Successful Treatment of Myeloid Sarcoma in an Elderly Patient with Myelodysplastic Syndrome with Reduced-Dose Azacitidine. Reviewed

Sato K, Tsukada N, Inamura J, Komatsu S, Sato K, Yamamoto M, Shindo M, Moriichi K, Mizukami Y, Fujiya M, Torimoto Y, Okumura T

Case Rep Hematol   2021

EMA401, an angiotensin II type 2 receptor antagonist blocks visceral hypersensitivity and colonic hyperpermeability in rat model of irritable bowel syndrome. Reviewed

Nozu T, Miyagishi S, Nozu R, Ishioh M, Takakusaki K, Okumura T.

J Pharacol Sci   2021

Safety and efficacy of cold snare polypectomy for small colorectal polyps: A prospective randomized control trial and one-year follow-up study Reviewed

Ito T, Takahashi K, Tanabe H, Sato K, Goto M, Sato T, Tanaka K, Utsumi T, Fujinaga A, Kawamoto T, Yanagawa N, Moriichi K, Fujiya M, Okumura T.

Medicine   2021

Brain orexin improves intestinal barrier function via the vagal cholinergic pathway Reviewed

Okumura T, Nozu T, Ishioh M, Igarashi S, Kumei S, Ohhira M

Neurosci Lett   2020.1

A tumor-specific modulation of heterogeneous ribonucleoprotein A0 promotes excessive mitosis and growth in colorectal cancer cells. Reviewed

Konishi H, Fujiya M, Kashima S, Sakatani A, Dokoshi T, Ando K, Ueno N, Iwama T, Moriichi K, Tanaka H, Okumura T.

Cell Death Dis   2020

Cytomegalovirus jejunitis diagnosed by endoscopy and successfully treated without surgery in a patient with hematochezia Reviewed

Muto M, Saito S, Yanagawa N, Okumura T

Digest Liver Dis   2020

Ghrelin acts in the brain to block colonic hyperpermeability in response to lipopolysaccharide through the vagus nerve. Reviewed

Ishioh M, Nozu T, Igarashi S, Tanabe H, Kumei S, Ohhira M, Okumura T.

Neuropharmacology   2020

Serrated adenomas with a BRAF mutation in a young patient with familial adenomatous polyposis Reviewed

Moriichi K, Tanabe H, Ono Y, Kobayashi Y, Murakami Y, Iwama T, Kunogi T, Sasaki T, Takahashi K, Ando K, Ueno N, Kashima S, Takei H, Mizukami Y, Fujiya M, Okumura T

Int J Colorectal Dis   2020

Genetic alteration of colorectal adenoma-carcinoma sequence among gastric adenocarcinoma and dysplastic lesions in a patient with attenuated familial adenomatous polyposis. Reviewed

Tanabe H, Moriichi K, Takahashi K, Ono Y, Kobayashi Y, Murakami Y, Iwama T, Kunogi T, Sasaki T, Ando K, Ueno N, Kashima S, Takei H, Mizukami Y, Fujiya M, Okumura T

Mol Genet Genomic Med   2020

Resection for pancreatic cancer metastases contributes to survival: A case report with sequential tumor genotype profiling during the long-term postoperative course Reviewed

Sato H, Sasajima J, Okada T, Hayashi A, Kawabata H, Goto T, Koizumi K, Tamamura N, Tanabe H, Fujiya M, Chiba SI, Tanino M, Ono Y, Mizukami Y, Okumura T

Medicine   2020

Probiotic derived ferrichrome inhibits the growth of refractory pancreatic cancer cells. Reviewed

Kita A, Fujiya M, Konishi H, Tanaka H, Kashima S, Iwama T, Ijiri M, Murakami Y, Takauji S, Goto T, Sakatani A, Ando K, Ueno N, Ogawa N, Okumura T

Int J Oncol   2020

Genetic Tracing of Clonal Expansion and Progression of Pancreatic Ductal Adenocarcinoma: A Case Report and Multi-Region Sequencing Analysis. Reviewed

Tachibana S, Mizukami Y, Ono Y, Sugiyama Y, Okada T, Kitazaki A, Sasajima J, Tominaga M, Sakamoto J, Kimura K, Omori Y, Furukawa T, Kimura T, Tanaka S, Nagashima K, Karasaki H, Ohta T, Okumura T

Front Oncol   2020

Heterogenous Nuclear Ribonucleoprotein H1 Promotes Colorectal Cancer Progression through the Stabilization of mRNA of Sphingosine-1-Phosphate Lyase 1. Invited Reviewed

Takahashi K, Fujiya M, Konishi H, Murakami Y, Iwama T, Sasaki T, Kunogi T, Sakatani A, Ando K, Ueno N, Kashima S, Moriichi K, Tanabe H, Okumura T

Int J Mol Sci   2020

Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR Reviewed

Ono Y, Hayashi A, Maeda C, Suzuki M, Wada R, Sato H, Kawabata H, Okada T, Goto T, Karasaki H, Mizukami Y, Okumura T

Sci Rep   2020

Brain metastasis from hepatic cholangiolocellular carcinoma in a young female without chronic liver disease Reviewed

Hasebe T, Nakajima S, Sawada K, Okumura T

Dig Liver Dis   2020

Digital PCR-based plasma cell-free DNA mutation analysis for early-stage pancreatic tumor diagnosis and surveillance. Reviewed

Okada T, Mizukami Y, Ono Y, Sato H, Hayashi A, Kawabata H, Koizumi K, Masuda S, Teshima S, Takahashi K, Katanuma A, Omori Y, Iwano H, Yamada M, Yokochi T, Asahara S, Kawakubo K, Kuwatani M, Sakamoto N, Enomoto K, Goto T, Sasajima J, Fujiya M, Ueda J, Matsumoto S, Taniue K, Sugitani A, Karasaki H, Okumura T

J Gastroenterology   2020

The endoscopic diagnosis of mucosal healing and deep remission in inflammatory bowel disease. Invited Reviewed

Moriichi K, Fujiya M, Okumura T

Dig Endscopy   2020

Centrally administered orexin prevents lipopolysaccharide and colchicine induced lethality via the vagal cholinergic pathway in a sepsis model in rats Reviewed

Igarashi S, Nozu T, Ishioh M, Kumei S, Saito T, Toki Y, Hatayama M, Yamamoto M, Shindo M, Tanabe H, Okumura T.

Biochem Pharmacol   2020

Endoscopic finding of a lace pattern in a case of Epstein-Barr virus-associated early gastric carcinoma Reviewed

Kobayashi Y, Tanabe H, Ando K, Fujiya M, Okumura T

Gastrointestinal Endosc   2020

Bacteria-derived ferrichrome inhibits tumor progression in sporadic colorectal neoplasms and colitis-associated cancer. Reviewed

Iwama T, Fujiya M, Konishi H, Tanaka H, Murakami Y, Kunogi T, Sasaki T, Takahashi K, Ando K, Ueno N, Kashima S, Moriichi K, Tanabe H, Okumura T

Cancer Cell Int   2020

Losartan improves visceral sensation and gut barrier in a rat model of irritable bowel syndrome. Reviewed

Nozu T, Miyagishi S, Nozu R, Takakusaki K, Okumura T.

Neurogastroenterol Mobil   2020

5-HT2A receptors but not cannabinoid receptors in the central nervous system mediate levodopa-induced visceral antinociception in conscious rats. Reviewed

Okumura T, Nozu T, Ishioh M, Igarashi S, Kumei S, Ohhira M.

Naunyn Schmiedebergs Arch Pharmacol   2020

Adenosine A1 receptor agonist induces visceral antinociception via 5-HT1A, 5-HT2A, dopamine D1 or cannabinoid CB1 receptors, and the opioid system in the central nervous system. Reviewed

Okumura T, Nozu T, Ishioh M, Igarashi S, Kumei S, Ohhira M.

Physiol Behav   2020

Central oxytocin signaling mediates the central orexin-induced visceral antinociception through the opioid system in conscious rats. Reviewed

Okumura T, Nozu T, Kumei S, Ohhira M

Physiol Behav   2019

Utility of “liquid biopsy” using pancreatic juice for early detection of pancreatic cancer Reviewed

Okada T, Iwano H, Ono Y, Karasaki H, Sato T, Yamada M, Omori Y, Sato H, Hayashi A, Kawabata H, Goto T, Sasajima J, Takauji S, Nagashima N, Mizukami Y, Okumura T.

Endoscopy Int Open   2019

Successful medical treatment for a Crohn’s disease patient with a perforation by a second-generation patency capsule Reviewed

Tanabe H, Andoh K, OhdairaH, Suzuki Y, Konuma I, Ueno N, Fujiya M, Okumura T

Endoscopy Int Open   2019

Endoscopic fine-needle aspitration is usefil for the treatment of pneumatosis cystoides intestinalis with intussusception Reviewed

Takahashi K, Fujiya M, Ueno N, Ando K, Kashima S, Moriichi K, Okumura T

Am J Gastroenterol   2019

Pioglotazone improves visceral sensation and colonic permeabolity in a a rat model of irritable bowel syndrome Reviewed

Nozu T, Miyagishi S, Nozu R, Takakusaki K, Okumura T

J Pharmacol Sci   2019

Pathways of Progression From Intraductal Papillary Mucinous Neoplasm to Pancreatic Ductal Adenocarcinoma Based on Molecular Features. Reviewed

Omori Y, Ono Y, Tanino M, Karasaki H, Yamaguchi H, Furukawa T, Enomoto K, Ueda J, Sumi A, Katayama J, Muraki M, Taniue K, Takahashi K, Ambo Y, Shinohara T, Nishihara H, Sasajima J, Maguchi H, Mizukami Y, Okumura T, Tanaka S

Gastroenterology   2019

The incidence and risk factors of venous thromboembolism in patients with inflammatory bowel disease: A prospective multicenter cohort study Reviewed

Ando K, Fujiya M, Nomura Y, Inaba Y, Sugiyama Y, Kobayashi Y, Iwama T, Ijiri M, Takahashi K, Ueno N, Kashima S, Moriichi K, Tanabe H, Mizukami Y, Akasaka K, Fujii S, Yamada S, Nakase H, Okumura T

Digestion   2019

Identification of Heterozygous p.Y150C and p.V274M Mutations in HJV Gene in a Japanese Patient with Mild Phenotype of Juvenile tHemochromatosis: A Case Report Reviewed

Kawaguchi T, Ikuta K, Tatsumi Y, Toki Y, Hayashi H, Tonan T, Ohtake T, Hoshino S, Naito M, Kato K, Okumura T, Torimura T

Hepatol Res   2019

Skeletal muscle mass is associated with toxicity, treatment tolerability, and additional or subsequent therapies in patients with hepatocellular carcinoma receiving sorafenib treatment. Reviewed

Sawada K, Saitho Y, Hayashi H, Hasebe T, Nakajima S, Ikuta K, Fujiya M, Okumura T

JGH Open   2019

Hepatitis B virus (HBV) reactivation in an acute lymphoblastic leukemia patient despite being vaccinated against HBV in infancy Reviewed

Yamamoto M, Ikuta K, Sawada K, Shindo M, Torimoto Y, Okumura T

Dig Liver Dis   2019

Novel automated measuring system for evaluating labile plasma iron in serum Invited Reviewed

Saito T, Ikuta K, Hatayama M, Shibusa K, Matsui K, Tanaka R, Toki Y, Kato D2, Iizuka N, Okumura T

Ann Clin Biochem   2019

Dehydroepiandrosterone sulfate improves visceral sensation and gut barrier in a rat model of irritable bowel syndrome Reviewed

Nozu T, Miyagishi S, Nozu R, Takakusaki K, Okumura T

Eur J Pharmacol   2019

Autofluorescence Imaging Reflects the Nuclear Enlargement of Tumor Cells as well as the Cell Proliferation Ability and Aberrant Status of the p53, Ki-67, and p16 Genes in Colon Neoplasms Reviewed

Moriichi K, Fujiya M, Kobayashi Y, Murakami Y, Iwama T, Kunogi T, Sasaki T7, Ijiri M, Takahashi K, Tanaka K, Sakatani A1, Ando K2, Nomura Y, Ueno N4, Kashima S, Ikuta K, Tanabe H, Mizukami Y, Saitoh Y, Okumura T

Molecules   2019

Non-alcoholic fatty liver disease is a potential risk factor for liver injury caused by immune checkpoint inhibitor Reviewed

Sawada K, Hayashi H, Nakajima N, Hasebe T, Fujiya M, Okumura T

J Gastroenterol Hepatol   2019

Repeated Perforation of the Gallbladder in a Patient with Hepatocellular Carcinoma Receiving Lenvatinib. Reviewed

Honda S, Saitho Y, Sawada K, Hasebe T, Nakajima S, Okumura T

Intern Med   2019

Metachronous intraductal papillary mucinous neoplasms disseminate via the pancreatic duct following resection Reviewed

Nagai, K., Mizukami, Y., Omori, Y. Hayashi T, Okumura T, Maguchi H, Katanuma A

Modern Pathol   2019

Genetic analysis of postoperative recurrence of pancreatic cancer potentially owing to needle tract seeding during EUS-FNB Reviewed

Kawabata H, Miyazawa Y, Sato H, Okada T, Hayashi A, Iwama T, Fujibayashi S, Goto T, Sasajima J, Takauji S, Fujiya M, Torimoto Y, Tanino M, Omori Y, Ono Y, Karasaki H, Mizukami M and Okumura T

Endosc Int open   2019

Gastric submucosa-invasive carcinoma associated with Epstein-Barr virus and endoscopic submucosal dissection: A case report. Reviewed

Kobayashi Y, Kunogi T, Tanabe H, Murakami Y, Iwama T, Sasaki T, Takahashi K, Ando K, Nomura Y, Ueno N, Kashima S, Moriichi K, Takei H, Fujiya M, Okumura T

World J Gastrointest Oncol   2019

Long-term growth of intrahepatic papillary neoplasms: A case report. Reviewed

Hasebe T, Sawada K, Hayashi H, Nakajima S, Takahashi H, Hagiwara M, Imai K, Yuzawa S, Fujiya M, Furukawa H, Okumura T

World J Gastroenterol.   2019

Long-Chain Polyphosphate Is a Potential Agent for Inducing Mucosal Healing of the Colon in Ulcerative Colitis. Reviewed

Fujiya M, Ueno N, Kashima S, Tanaka K, Sakatani A, Ando K, Moriichi K, Konishi H, Kamiyama N, Tasaki Y, Omura T, Matsubara K, Taruishi M, Okumura T.

Clin Pharmacol Ther   2019

Butyrate inhibits visceral allodynia and colonic hyperpermeability in rat models of irritable bowel syndrome. Reviewed

Nozu T, Miyagishi S, Nozu R, Takakusaki K, Okumura T.

Sci Rep   2019

Lymph Node Metastasis From Gastroesophageal Cancer Successfully Treated by Nivolumab: A Case Report of a Young Patient. Reviewed

Kashima S, Tanabe H, Tanino M, Kobayashi Y, Murakami Y, Iwama T, Sasaki T, Kunogi T, Takahashi K, Ando K, Ueno N, Moriichi K, Fukudo M, Tasaki Y, Hosokawa M, Mizukami Y, Fujiya M, Okumura T.

Front Oncol   2019

White coat status is a predictive marker for post-esophageal endoscopic submucosal dissection stricture: a retrospective study. Reviewed

Takahashi K, Fujiya M, Ueno N, Saito T, Sugiyama Y, Murakami Y, Iwama T, Sasaki T, Ijiri M, Tanaka K, Sakatani A, Ando K, Nomura Y, Kashima S, Goto M, Moriichi K, Okumura

Esophagus   2019

A case of gastric carcinoma with lymphoid stroma diagnosed by an endoscopic ultrasound-guided fine-needle biopsy. Reviewed

Tanabe H, Ando K, Sutoh D, Ohta K, Ohdaira H, Suzuki Y, Fujiya M, Okumura T

J Clin Ultrasound   2019

Successful Treatment of Nivolumab-related Cholangitis with Prednisolone: A Case Report and Review of the Literature. Reviewed

Sawada K, Shonaka T, Nishikawa Y, Hasegawa K, Hayashi H, Hasebe T, Nakajima S, Ikuta K, Fujiya M, Furukawa H, Okumura T

Intern Med   2019

Minute duodenal metastasis in a patient with thoracic esophageal squamous cell carcinoma successfully treated with chemoradiotherapy. Reviewed

Ando K, Fujiya M, Okumura T

Dig Endosc   2018

Altered colonic sensory and barrier functions by CRF: roles of TLR4 and IL-1 Reviewed

Nozu T, Miyagishi S, Nozu R, Takakusaki K, Okumura T

J Endocrinol   2018

A Case of Alpha-Fetoprotein-Producing Adenocarcinoma of the Esophagogastric Junction in which Long-Term Survival Was Achieved by Means of Individualized Multidisciplinary Therapy. Reviewed

Tanaka K, Fujiya M, Ijiri M, Takahashi K, Ando K, Nomura Y, Ueno N, Kashima S, Goto T, Sasajima J, Ito T, Moriichi K, Mizukami Y, Tanabe H, Okumura T

J Gastrointest Cancer   2018

A glucagon-like peptide-1 analog, liraglutide improves visceral sensation and gut permeability in rats Reviewed

Nozu T, Miyagishi S, Kumei S, Nozu R, Takakusaki K, Okumura T.

J Gastroenterol Hepatol   2018

Polymorphism of Receptor-Type Tyrosine-Protein Phosphatase Delta gene in the development of non-alcoholic fatty liver disease Reviewed

Nakajima S, Tanaka H, Sawada K, Hayashi H, Hasebe T, Abe M, Hasebe C, Fujiya M, Okumura T.

J Gastroentero Hepatol   2018

Lovastatin inhibits visceral allodynia and increased colonic permeability induced by lipopolysaccharide or repeated water avoidance stress in rats. Reviewed

Nozu T, Miyagishi S, Kumei S, Nozu R, Takakusaki K, Okumura T.

Eur J Pharmacol.   2018

Prostaglandin I2 suppresses the development of diet-induced nonalcoholic steatohepatitis in mice. Reviewed

Kumei S, Yuhki KI, Kojima F, Kashiwagi H, Imamichi Y, Okumura T, Narumiya S, Ushikubi F

FASEB J   2018

Echinococcosis infection diagnosed based on the histological findings of a lymph node involvement obtained by EUS-FNA. Reviewed

Moriichi K, Fujiya M, Goto T, Okumura T

Endosc Ultrasound   2018

Ghrelin acts centrally to induce an antinociceptive action during colonic distension through the orexinergic, dopaminergic and opioid systems in conscious rats. Reviewed

Okumura T, Nozu T, Kumei S, Takakusaki K, Ohhira M

Brain Res   2018

Pseudogout Attack after Pegfilgrastim Administration in Anaplastic Large Cell Lymphom Reviewed

Hatayama M, Ikuta K, Ishioh M, Saito T, Toki Y, Yamamoto M, Shindo M, Torimoto Y, Okumura T

Intern Med   2018

An elevated expression of serum exosomal microRNA-191, - 21, -451a of pancreatic neoplasm is considered to be efficient diagnostic marker. Reviewed

Goto T, Fujiya M, Konishi H, Sasajima J, Fujibayashi S, Hayashi A, Utsumi T, Sato H, Iwama T, Ijiri M, Sakatani A, Tanaka K, Nomura Y, Ueno N, Kashima S, Moriichi K, Mizukami Y, Kohgo Y, Okumura T

BMC Cancer   2018

The incidence and risk factors of venous thromboembolism in Japanese inpatients with inflammatory bowel disease: a retrospective cohort study. Reviewed

Ando K, Fujiya M, Nomura Y, Inaba Y, Sugiyama Y, Iwama T, Ijiri M, Takahashi K, Tanaka K, Sakatani A, Ueno N, Kashima S, Moriichi K, Mizukami Y, Okumura T.

Intest Res   2018

Metformin inhibits visceral allodynia and increased gut permeability induced by stress in rats. Reviewed

Nozu T, Miyagishi S, Kumei S, Nozu R, Takakusaki K, Okumura T.

J Gastroenterol Hepatol   2018

Role of the cannabinoid signaling in the brain orexin- and ghrelin-induced visceral antinociception in conscious rats. Reviewed

Okumura T, Nozu T, Kumei S, Ohhira M

J Pharmacol Sci   2018

Vonoprazan-based triple therapy is non-inferior to susceptibility-guided proton pump inhibitor-based triple therapy for Helicobacter pylori eradication. Reviewed

Tanabe H, Yoshino K, Ando K, Nomura Y, Ohta K, Satoh K, Ichiishi E, Ishizuka A, Otake T, Kohgo Y, Fujiya M, Okumura T

Ann Clin Microbiol Antimicrob   2018

Takayasu's arteritis associated with eosinophilic gastroenteritis, possibly via the overactivation of Th17. Reviewed

Fujiya M, Kashima S, Sugiyama Y, Iwama T, Ijiri M, Tanaka K, Takahashi K, Ando K, Nomura Y, Ueno N, Goto T, Moriichi K, Mizukami Y, Okumura T, Sasajima J, Fujishiro D, Okamoto K, Makino Y.

Gut Pathogen   2018

Pilot study of endoscopic retrograde 3-dimensional - computed tomography enteroclysis for the assessment of Crohn's disease. Reviewed

Tanabe H, Ito T, Inaba Y, Ando K, Nomura Y, Ueno N, Kashima S, Moriichi K, Fujiya M, Okumura T.

Eur J Radiol Open   2017

Inverted gastric adenocarcinoma of fundic gland mucosa type colliding with well differentiated adenocarcinoma: A case report. Reviewed

Takahashi K, Fujiya M, Ichihara S, Moriichi K, Okumura T.

Medicine (Baltimore)   2017

Ferrichrome identified from Lactobacillus casei ATCC334 induces apoptosis through its iron-binding site in gastric cancer cells. Reviewed

Ijiri M, Fujiya M, Konishi H, Tanaka H, Ueno N, Kashima S, Moriichi K, Sasajima J, Ikuta K, OkumuraT.

Tumour Biol   2017

Efficacy of Vonoprazan-Based Triple Therapy for Helicobacter pylori Eradication: A Multicenter Study and a Review of the Literature. Reviewed

Tanabe H, Ando K, Sato K, Ito T, Goto M, Sato T, Fujinaga A, Kawamoto T, Utsumi T, Yanagawa N, Ichiishi E, Otake T, Kohgo Y, Nomura Y, Ueno N, Sugano H, Kashima S, Moriichi K, Fujiya M, Okumura T

Dig Dis Sci   2017

The endoscopic findings of the upper gastrointestinal tract in patients with Crohn's disease. Reviewed

Nomura Y, Moriichi K, Fujiya M, Okumura T.

Clin J Gastroenterol   2017

Second-line therapy for Helicobacter pylori eradication causing antibiotic-associated hemorrhagic colitis. Reviewed

Tanaka K, Fujiya M, Sakatani A, Fujibayashi S, Nomura Y, Ueno N, Kashima S, Goto T, Sasajima J, Moriichi K, Okumura T.

Ann Clin Microbiol Antimicrob   2017

Tegafur-uracil-induced rapid development of advanced hepatic fibrosis. Reviewed

Honda S, Sawada K, Hasebe T, Nakajima S, Fujiya M, Okumura T.

World J Gastroenterol   2017

Angioimmunoblastic T-cell lymphoma and hypereosinophilic syndrome with FIP1L1/PDGFRA fusion gene effectively treated with imatinib: A case report. Reviewed

Yamamoto M, Ikuta K, Toki Y, Hatayama M, Shindo M, Torimoto Y, Okumura T.

Medicine (Baltimore).   2017

Esophageal anisakiasis mimicking gastroesophageal reflux disease. Reviewed

Uehara A, Okumura T

Am J Gastroenterol   2017

Repeated water avoidance stress induces visceral hypersensitivity; role of IL-1, IL-6 and peripheral corticotropin-releasing factor. Reviewed

Nozu T, Miyagishi S, Nozu R, Takakusaki K, Okumura T

J Gastroenterol Hepatol   2017

Reticulocyte hemoglobin equivalent as a potential marker for diagnosis of iron deficiency. Reviewed

Toki Y, Ikuta K, Kawahara Y, Niizeki N, Kon M, Enomoto M, Tada Y, Hatayama M, Yamamoto M, Ito S, Shindo M, Kikuchi Y, Inoue M, Sato K, Fujiya M, Okumura T.

Int J Hematol   2017

Cold exposure related fever with MEFV gene mutation. Reviewed

Kumei S, Nozu T, Ohhira M,Okumura T

Intern Med   2017

The efficacy of autofluorescence imaging in the diagnosis of colorectal diseases. Reviewed

Moriichi K, Fijiya M, Okumura T

Clin J Gastroenterol   2016

A case of liver hemangioma with markedly reduced tumor size after Metformin treatment - A case report – Reviewed

Ono M, Sawada K, Okumura T

Clin J Gastroenterol   2016

Syphilis infection throughout the whole gastrointestinal tract. Reviewed

Ijiri M, Fujiya M, Ueno N, Kashima S, Watari T, Fujii S, Okumura T

Endoscopy   2016

Pancreatic metastasis of angiosarcoma (Stewart-Treves syndrome) diagnosed using endoscopic ultrasound-guided fine needle aspiration: A case report Reviewed

Sasajima J, Uehara J, Goto T, Fujibayashi S, Koizumi K, Mizukami Y, Ishida-Yamamoto A, Fujiya M, Okumura T

Medicine (Baltimore)   2016

Ramosetron Reduces Symptoms of Irritable Bowel Syndrome With Diarrhea and Improves Quality of Life in Women. Reviewed

Fukudo S, Kinoshita Y, Okumura T, Ida M, Akiho H, Nakashima Y, Nishida A, Harumm K.

Gastroenterology   2016

Effect of ramosetron on female patients with IBS with diarrhea: Phase III, long term study Reviewed

Fukudo s, Kinoshita Y, Okumura T, Ida M, Akiho H Nakashima Y, Nishida A, Haruma K

J Gastroenterol   2016

Levodopa acts centrally to induce an antinociceptive action against colonic distension through activation of D2 dopamine receptors and the orexinergic system in the brain in conscious rats. Reviewed

Okumura T, Nozu T, Kumei S, Takakusaki K, Miyagishi S, Ohhira M.

J Pharmacol Sci   130 ( 2 )   123 - 127   2016

Adenosine A1 receptors mediate the intracisternal injection of orexin-induced antinociceptive action against colonic distension in conscious rats. Reviewed

Okumura T, Nozu T, Kumei S, Takakusaki K, Miyagishi S, Ohhira M.

J Neurol sci   362   306 - 310   2016

Lipopolysaccharide induces visceral hypersensitivity: role of interleukin-1, interleukin-6, and peripheral corticotropin-releasing factor in rats. Reviewed

Nozu T, Miyagishi S, Nozu R, Takakusaki K, Okumura T.

J Gastroenterol   2016

Bullous pemphigoid and percutaneous endoscopic gastrostomy. Reviewed

Nozu T, Okumura T

Geriatr Gerontol Int   2016

Corticotropin-releasing factor receptor type 1 and type 2 interaction in irritable bowel syndrome Reviewed

Nozu T, Okumura T

J Gastroenterol   2015

A case report on reversible Pelger-Huët anomaly depending on serum free fraction of valproic acid Reviewed

Suzuki K, Hiramoto A, Okumura T

Brain Dev   37 ( 3 )   344 - 346   2015

Evidence-based clinical practice guidelines for irritable bowel syndrome Reviewed

Fukudo S, Kaneko H, Akiho H, Inamori M, Endo Y, Okumura T, Kanazawa M, Kamiya T, Sato K, Chiba T, Furuta K, Yamato S, Arakawa T, Fujiyama Y, Azuma T, Fujimoto K, Mine T, Miura S, Kinoshita Y, Sugano K, Shimosegawa T

J Gastroenterol   50 ( 1 )   11 - 30   2015

Retropharyngeal calcified tendinitis Reviewed

Nozu T, Kumei S, Ohhira M, Okumura T

Intern Med   2015

Screening for Major Depressive Disorder with the Patient Health Questionnaire (PHQ-9 and PHQ-2) in an Outpatient Clinic Staffed by Primary Care Physicians in Japan: A Case Control Study Reviewed

Suzuki K, Kumei S, Ohhira M, Nozu T, Okumura T

PLos One   2015

Colorectal distention induces acute and delayed visceral hypersensitivity: role of peripheral corticotropin-releasing factor and interleukin-1 in rats Reviewed

Nozu T, Kumei S, Miyagishi S, Takakusaki K, Okumura T

J Gastrenterol   2015

Antinociceptive action againt colonic dissension by brain orexin in conscious rats Reviewed

Okumura T, Nozu T, Kumei S, Takakusaki K, Miyagishi S, Ohhira M

Brain Res   2015

Evaluation of Kampo medicine in the clinical practice guideline for irritable bowel syndrome. Reviewed

Fukudo S, Kaneko H, Akiho H, Inamori M, Endo Y, Okumura T, Kanazawa M, Kamiya T, Sato K, Chiba T, Furuta K, Yamato S, Arakawa T, Fujiyama Y, Azuma T, Fujimoto K, Mine T, Miura S, Kinoshita Y, Watanabe M, Sugano K, Shimosegawa T.

J Gastroenterol   50 ( 7 )   817 - 818   2015

Involvement of the dopaminergic system in the central orexin-induced antinociceptive action against colonic distension in conscious rats. Reviewed

Okumura T, Nozu T, Kumei S, Takakusaki K, Miyagishi S, Ohhira M.

Neurosci Lett   2015

Brainstem control of locomotion and muscle tone with special reference to the role of the mesopontine tegmentum and medullary reticulospinal systems. Reviewed

Takakusaki K, Chiba R, Nozu T, Okumura T.

J Neural Transm   2015

Water avoidance stresss induces visceral hyposensitiveity through peripheral corticotropin releasing factor receptor type 2 and central dopamine D2 receptor in rats. Reviewed

Nozu T, Miyagishi S, Nozu R, Takakusaki K, Okumura T.

Neurogastroenterol Motil   2015

A balance theory of peripheral corticotropin-releasing factor receptor type 1 and type 2 signaling to induce colonic contractions and visceral hyperalgesia in rats Reviewed

Nozu T, Takakusaki K, Okumura T

Endocrinology   155 ( 12 )   4655 - 4664   2014

IBSの疫学と臨床上の注意点 Invited

奥村利勝

消化器の臨床   2014

過敏性腸症候群の病態　脳腸相関から考える Invited Reviewed

奥村利勝

日本消化器病学会雑誌   2014

An adult patient with cyclic vomiting syndrome successfully treated with oral sumatriptan Reviewed

Okumura T, Ohhira M, Kumei S, Nozu T

Am J Gastroenterol   109 ( 2 )   292 - 293   2014

Urocortin 2 blocks the suppression of gastric antral contractions induced by lipopolysaccharide in freely moving conscious rats Reviewed

Tsukasa Nozu, Kaoru Takakusaki, Toshikatsu Okumura

Regul Pept   190-191   12 - 17   2014

RS3PEとリウマチ性多発筋痛症との鑑別 Invited

奥村利勝

日本医事新報   4685   64 - 66   2014

Water-avoidance stress enhances gastric contractions in freely moving conscious rats: role of peripheral CRF receptors. Reviewed

Nozu T, Kumei S, Takakusaki K, Okumura T

J Gastroenterol   49 ( 5 )   799 - 805   2014

A higher frequency of lumbar OPLL in elderly in an outpatient clinic in Japan Reviewed

Okumura T, Ohhira M, Kumei S, Nozu T

Int J Gen Med   6   729 - 732   2013

海外論文解説 Invited

粂井志麻、奥村利勝

分子消化器病   2013

Post-infectious FDの病因を探る Invited

奥村利勝

分子消化器病   10 ( 3 )   230 - 235   2013

Peripheral corticotropin-releasing factor (CRF) induces stimulation of gastric contractions in freely moving conscious rats: role of receptor subtype 1 and 2. Reviewed

Nozu T, Tsuchiya Y, Kumei S, Takakusaki K, Okumura T

Neurogastroenterol Motil   25 ( 2 )   190 - 197   2013

RS3PE-PMRとの相違

奥村利勝

リウマチ科   2012

両側四肢にpitting edemaをきたした患者の鑑別診断

奥村利勝

Modern Physician   2012

High rate of smoking in female patients with Mondor's disease in an outpatient clinic in Japan Reviewed

Okumura T, Ohhira M, Nozu T

Int J Gen Med   5   735 - 738   2012

The rate of polymyalgia rheumatica (PMR) and remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome in a clinic where primary care physcians are working in Japan Reviewed

Okumura T, Tanno S, Ohhira M, Nozu T

Rheumatol Int   32 ( 6 )   1695 - 1699   2012

Chronic right lower abdominal pain due to lumbar ossilation of the posterior longitudinal ligament (OPLL) Reviewed

Okumura, Ebisawa K, Ohhira M, Nozu T, Tsuchiya Y, Inoue M, Tanaka M

Am J Gastroenterol   107 ( 1 )   142 - 143   2012

Endogenous orexin-A in the brain mediates 2-Deoxy-D-glucose-induced stimulation of gastric motility in freely moving conscious rats Reviewed

Nozu T, Tsuchiya Y, Kumei S, Takakusaki K, Ataka K, Fujimiya M, Okumura T

J Gastroenterol   47 ( 4 )   404 - 411   2012

Epiploic appendagitis as an uncommon cause of lower abdominal pain Reviewed

Okumura T, Ohhira M, Tsuchiya Y, Kikuchi Y, Kohgo Y, Yoshihara S, Okabe H, Nozu T

Open J Gastroenterol   2   31 - 33   2012

IL-1 receptor antagonist blocks the lipopolysaccharide-induced inhibition of gastric motikity ub freely moving conscious rats Reviewed

Tsuchiya Y, Nozu T, Kumei S, Ohhira M, Okumura T

Dig Dis Sci   57 ( 10 )   2555 - 2561   2012

Peritoneal loose body Reviewed

Nozu T, Okumura T

Intern Med   51   2057 - 2057   2012

機能性消化管障害の疫学

奥村利勝

Modern Physician   2011

うつ病の治療ー初処方時の注意点

奥村利勝

Modern Physician   2011

FDの説明：病気の説明　患者にどう説明するのがいいのでしょうか？　

奥村利勝

FD診療Q/A 本郷道夫編　日本医事新報社　   2011

Modulatory effects of the GABAergic basal ganglia neurons on the PPN and the muscle tone inhibitory system in cats Reviewed

Takakusaki K, Obara K, Nozu T, Okumura T

Arch Ital Biol   2011

Role of brain orexin in the pathophysiology of functional gastrointestinal disorders Invited Reviewed

Okumura T, Nozu T

J Gastroenterol Hepatol   2011

Visceral sensation and irritable bowel syndrome with special reference to comparison with functional abdominal pain syndrome Invited Reviewed

Nozu T, Okumura T

J Gastroenterol Hepatol   2011

Central orexin-A increases colonic motility in conscious rats Reviewed

Nozu T, Kumei, Takakusaki K, Ataka K, Fujimiya M, Okumura T

Neurosci Lett   2011

Stress-induced hemorrhagic gastric ulcer after successful Helicobacter pylori eradiation: two case reports Reviewed

Moriya M, Uehara A, Okumura T, Miyamoto M, Kohgo Y

J Med Case Reports   2011

Role of lipid droplet proteins in liver steatosis Reviewed

Okumura T

J Physiol Biochem   2011

Severe hyponatricmia in association with I-131 therapy in patient wuth metastatic thyroid cancer Reviewed

NozuT, Yoshida Y, Ohhira M, Okumura T

Intern med   2011

Prevalence of functional dyspepsia in an outpatient clinic with primary care physicians in Japan Reviewed

Okumura T,Tanno S,Ohhira M,Tanno S.

J Gastroenterology   45 ( 2 )   187 - 194   2010

Mechanisms by which thiazolidinediones induce anti-cancer effects in cancers in digestive organs. Reviewed

Okumura T

J Gastroenterology   45 ( 11 )   1097 - 1102   2010

Acquired factor V inhibitor in a patient with a mechanical aortic valve under warfarin therapy Reviewed

Nozu T,Mita H,Okumura T

Intern Med   49 ( 20 )   2229 - 2233   2010

Thiazolidinediones enhance vascular endothelial growth factor expression and induce cell growth inhibition in non-small-cell lung cancer cells Reviewed

Yoshizaki T,Motomura W,Tanno S,Kumei S,Yoshizaki Y,Tanno S,Okumura T

J Exp Clin Cancer Res   29   22 - 22   2010

大学病院総合診療部におけるSSRIの処方の頻度と治療成績

丹野幸恵、大平賀子、土屋慶容、粂井志麻、丹野誠志、奥村利勝

消化器心身医学   2010

低酸素応答シグナル伝達

奥村利勝

分子消化器病   2010

機能性消化管障害の臨床-疫学とその臨床的意儀-

奥村利勝

日本内科学会雑誌   2010

過敏性腸症候群の治療

奥村利勝

腸疾患診療のStrategy 斉藤裕輔編　日本メディカルセンター   2010

PPARγアゴニストの臨床応用：抗腫瘍効果

奥村利勝

日本臨床   2010

Charateristics in patients with headache in an outpatient clinic in Japan Reviewed

Okumura T, Tanno S, Ohhira M, Tanno S, Nozu T

Asia Pac Fam Med   2010

Incidence of synchronous and metachronous pancreatic carcinoma in 168 patients with branch duct intraductal papillary mucinous neoplasm. Reviewed

Tanno S, Nakano Y, Sugiyama Y, Nakamura K, Sasajima J, Koizumi K, Yamazaki M, Nishikawa T, Mizukami Y, Yanagawa N, Fujii T, Obara T, Okumura T, Kohgo y

Pancreatology   2010

Tumor doubling time in two cases of main duct intraductal papillary-mucinous neoplasms of the pancreas.

Tanno S, Sasajima J, Koizumi K, Yanagawa N, Nakano Y, Osanai M, Mizukami Y, Fujii T, Obara T, Okumura T, Kohgo Y.

Hepatogastroenterology   56   1545 - 1548   2009

A Jak2 inhibitor, AG490, reverses lipin-1 suppression by TNF-alpha in 3T3-L1 adipocytes. Reviewed

Tsuchiya Y, Takahashi N, Yoshizaki T, Tanno S, Ohhira M, Motomura W, Tanno S, Takakusaki K, Kohgo Y, Okumura T

Biochem Biophys Res Commun   382   348 - 352   2009

Troglitazone increases expression of E-cadherin and claudin 4 in human pancreatic cancer cells. Reviewed

Kumei S, Motomura W, Yoshizaki T, Takakusaki K, Okumura T.

Biochem Biophys Res Commun   380   614 - 619   2009

Frequent early discontinuation of SSRI prescribed by primary care physicians in young males in Japan.

Tanno S, Ohhira M, Tsuchiya Y, Takeuchi T, Tanno S, Okumura T.　

Intern Med   48   1263 - 1266   2009

分枝型IPMNを膵癌高危険群として集約した検診体系の検討

丹野誠志，小泉一也，西川智哉，杉山祥晃，笹島順平，中野靖弘，水上裕輔，柳川伸幸，藤井常志，奥村利勝，高後裕

消化器科   2009

摂食肥満の分子機構を探る

奥村利勝

分子消化器病   2009

切除不能進行膵癌に対するTS1／GEMおよびUFT／GEM併用療法の検討

笹島順平，丹野誠志，小泉一也，中野靖弘，羽廣敦也，藤井常志，杉山祥晃，中村和正，西川智哉，水上裕輔，奥村利勝，高後裕

癌と化学療法   2009

Tissue distribution of a collectin CL-K1 in murine tissues.

Motomura W, Yoshizaki T, Ohtani K, Okumura T, Fukuda M, Fukuzawa J , Mori K, Jang S-J, Nomura N, Yoshida I, Suzuki Y, Kohgo Y, Wakamiya N.

J Histchem Cytochem   56   243 - 252   2008

Natural History of Branch Duct Intraductal Papillary-Mucinous Neoplasms of the Pancreas without Mural Nodules: Long-term Follow-up Results. Reviewed

Tanno S, Nakano Y, Nishikawa T, Nakamura K, Sasajima J, Minoguchi M, Mizukami Y, Yanagawa N, Fujii T, Obara T, Okumura T, Kohgo Y.

Gut   57   339 - 343   2008

Sonic hedgehog derived from human pancreatic cancer cells augments angiogenic function of endothelial progenitor cells. Reviewed

Minoguchi M, Nakamura K, Mizukami Y, Ii M, Sasajima J, Sugiyama Y, Nishikawa T, Nakano Y, Yanagawa N, Sato K, Maemoto A, Tanno S, Okumura T, Karasaki H, Kono T, Fujiya M, Ashida T, Chung DC, Kohgo Y.

Cancer Sci   99   1131 - 1138   2008

Role of orexin in central regulation of gastrointestinal functions. Reviewed

Okumura T, Takakusaki K.

J Gastroenterol   43   652 - 660   2008

Neurobiological Basis of Controlling Posture and Locomotion.

Takakusaki K, Okumura T.

Advanced Robotics   22   1629 - 1663   2008

Milk of calciumを伴った膵仮性嚢胞の1例

小泉一也、丹野誠志、柳川伸幸、小山内学、羽広敦也、中村和正、蓑口まどか、中野靖弘、水上裕輔、奥村利勝、高後 裕

日本消化器病学会誌   2008

消化とホルモン

奥村利勝

臨床検査   2008

運動機能から観た哺乳類の睡眠制御メカニズム

高草木薫、奥村利勝、小山純正

細胞工学   2008

脳腸相関からみた機能性胃腸症

奥村利勝

日本医事新報   2008

LPS nduces ADRP expression and lipid accumulation in the liver through Inhibition of fatty acid oxidation in mice. Reviewed

Ohhira M, Motomura W, Fukuda M, Yoshizaki T, Takahashi N, Tanno S, Wakamiya N, Kohgo Y, Kumei S, Okumura T

J Gastroenterol   42   969 - 978   2007

Intracisternal injection of orexin-A prevents ethanol-induced gastric mucosal damage in rats. Reviewed

Yamada H, Tannno S, Takakausaki K, Okumura T.

J Gastroenterology   42   336 - 341   2007

Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells. Reviewed

Nakano Y, Tanno S, Koizumi K, Nishikawa T, Nakamura K, Minoguchi M, Izawa T, Mizukami Y, Okumura T, Kohgo Y.

Br J Cancer   96   457 - 463   2007

A diacylglycerol kinase inhibitor, R59022, stimulates glucose transport through a MKK3/6-p38 signaling pathway in skeletal muscle cells. Reviewed

Takahashi N, Nagamine M, Tanno S, Motomura W, Kohgo Y, Okumura T

Biochem Biophys Res Commun   360   244 - 250   2007

OSCE実施例 ―旭川医科大学―OSCEの理論と実際

奥村利勝

OSCEの理論と実際．篠原出版   2007

消化管・膵生理機能調節における中枢神経系の役割：アポリポプロテインA-IV、Pancreatic polypeptide、オレキシンについて最近の進歩

奥村利勝

日本消化器病学会雑誌   2007

嚢胞壁の一部に微小浸潤癌を認めた分枝型IPMNの一例

西川智哉、丹野誠志、中野靖弘、中村和正、笹島順平、水上裕輔、奥村利勝、徳差良彦、三代川斎之、高後　裕

消化器画像   2007

A phase I study of oral uracil-tegafur prior to weekly intravenous gemcitabine in patients with advanced pancreatic cancer. Reviewed

Tanno S, Nakano Y, Osanai M, Koizumi K, Izawa T, Habiro A, Mizukami Y, Yanagawa N, Fujii T, Okumura T, Kohgo Y.

Chemotherapy   52 ( (2) )   98 - 102   2006

Up-regulation of ADRP in fatty liver in human and liver steatosis in mice fed with high fat diet. Reviewed

Motomura W, Inoue M, Ohtake T, Takahashi N Nagamine M, Tanno S, Kohgo Y, Okumura T.

Biochem Biophys Res Commun   340   1111 - 1118   2006

Neurobiological Basis of State-Dependent Control of Motor Behaviors.

Takakusaki K, Saitoh K, Nonaka S, Okumura T, Miyokawa N, and Koyama Y.

Sleep and Biological Rhythms   4   87 - 104   2006

夜寝ている時に腓腹筋や足の指がつれると訴える患者が来たら

奥村利勝

Modern Physician   2006

高脂肪食負荷マウス脂肪肝モデルにおけるPPARγの発現亢進

奥村利勝

日本臨床   2006

過敏性腸症候群の機能検査

奥村利勝

日本臨床   2006

からだがだるいと訴える患者をみたら

奥村利勝

Modern Physician   2006

機能性胃腸症 上腹部不定愁訴に対して

奥村利勝

Modern Physician   2006

Brain or gut ? : Site of action of adrenomedullin to regulate gut motility Reviewed

Okumura T.

J Gastroenterol   40   1161 - 1162   2005

A selective orexin-1 receptor antagonist, SB334867, blocks 2-DG -induced gastric acid secretion in rats. Reviewed

Yamada H, Takahashi N, Tanno S, Nagamine M, Takakusaki K, Okumura T,

Neurosci Lett   376   137 - 142   2005

Orexinergic projections to the midbrain mediate alternation of emotional behavioral states from locomotion to cataplexy. Reviewed

Takakusaki K, Takahashi K, Saitoh K, Harada H, Okumura T, Koyama Y

J Physiol   568   1003 - 1020   2005

Involvement of MEK-ERK signaling pathway in the inhibition of cell growth by troglitazone in human pancreatic cancer cells. Reviewed

Motomura W, Tanno S, Takahashi N, Nagamine M, Fukuda M, Kohgo Y, Okumura T.

Biochem Biophys Res Commun   332   89 - 94   2005

Activation of p38 Mitogen-Activated Protein Kinase is Necessary for Gemcitabine-Induced Cytotoxicity in Human Pancreatic Cancer Cells. Reviewed

Koizumi K, Tanno S, Nakano Y, Habiro A, Izawa T, Mizukami Y, Okumura T,

Anticancer Res   25   3347 - 3353   2005

Increased expression of PPARg in high fat diet-induced liver steatosis in mice. Reviewed

Inoue M, Ohtake T, Motomura W, Takahashi N, Hosoki Y, Miyoshi S, Suzuki Y, Saito H, Kohgo Y , Okumura T.

Biochem Biophys Res Commun   336   215 - 222   2005

部症状を主訴にする症例のプライマリーケア ―説明できる器質的疾患がない場合―．

奥村利勝

北海道プライマリーケア研究会会報   2005

特発性反応性低血糖の１症例

長峯美穂　高橋伸彦　井上充貴　高後　裕　奥村利勝

糖尿病   2005

胃潰瘍・胃炎モデルとこれを用いた研究

奥村利勝

分子消化器病   2005

脳内内因性orexin-Aは胃酸分泌の中枢性調節分子である

奥村利勝．山田裕人

消化管運動   2005

Image of the Month. Reviewed

Nozu T, Komiyama H, Okumura T.

Gastroenterology   127   1029 - 1029   2004

Growth arrest by troglitazone is mediated by p27Kip1 accumulation which is resulted from dual inhibition of proteasome activity and Skp2 expression in human hepatocellular carcinoma cells Reviewed

Motomura W, Takahashi N, Nagamine M, Sawamukai M, Tanno S, Kohgo Y, Okumura T.

Int J Cancer   108   41 - 46   2004

Involvement of p38 mitogen-activated protein kinase in gemcitabine-induced apoptosis in human pancreatic cancer cells. Reviewed

Habiro A, Tanno S, Koizumi K, Izawa T, Nakano Y, Osanai M, Mizukami M, Okumura T, and Kohgo Y.

Biochem Biophys Res Commun   316   71 - 77   2004

Serine/threonine Kinase AKT is frequently activated in human bile duct cancer and is associated with increased radioresistance. Reviewed

Tanno S, Yanagawa N, Habiro A, Koizumi K, Nakano Y, Osanai M, Mizukami Y, Okumura T, Testa JR, and Kohgo Y.

Cancer Res   64   3486 - 3490   2004

Inhibition of cell invasion and morphological change by troglitazone in cultured human pancreatic cancer cells. Reviewed

Motomura W, Nagamine M, Tanno S, Sawamukai M, Takahashi N, Kohgo Y, Okumura T.

J Gastroenterol   39   461 - 468   2004

心身症「日常病にどう対応しますか？

奥村利勝

治療   2004

Evidence for a role of basal ganglia in the regulation of REM sleep by electrical and chemical stimulation of for the pedunculopontine tegmental nucleus and the substania nigra pars reticulata in decrebrated cats Reviewed

Takakusaki K, Saito K, Harada H, Okumura T, Sakamoto T

Neuroscience   2004

膵胆管合流異常―残された問題―胆嚢粘膜過形成の発生時期に関する分子生物学的考察

丹野誠志、中野靖弘、小泉一也、小山内学、柳川伸幸、藤井常志、奥村利勝、小原　剛、高後　裕.

胆と膵   2004

香辛料嗜好と胃痛胃疾患

奥村利勝

総合臨床   2004

PPARgamma ligand-induced apoptosis through a p53 dependent mechanism in human gastric cancer cell Reviewed

Nahamine M, Okumura T, Tanno S, Sawamukai M, Motomura W, Takahashi N, Kohgo Y

Cancer Sci   2003

Troglitazone induces G1 arrest by p27Kip1 induction that is mediated by inhibition of proteasome in human gastric cancer cells Reviewed

Takeuchi S, Okumura T, Motomura W, Nagamine M, Takahashi N, Kohgo Y

Cancer Sci   2002

Requirement of intact disulfide bonds in orexin-A induced stimulation of gastric acid secretion that is mediated by OX1 receptor activation Reviewed

Okumura T, Takeuchi S, Motomura W, Yamada H, Egashira S, Asahi S, Kanatani A, Ihara M, Kohgo Y

Biochem Biophys Res Commun   2001

A novel anorectic chemical, cocaine-amphetamine^regulated transcript (CART), acts in the central nervous system to inhibit gastric acid secretion via brain CRF system Reviewed

Okumura T, Yamada H, Motomura W, Kohgo Y

Endocrinology   2000

Increased serum leptin levels in a diabetic patient with acute cholycystitis Reviewed

Moriya M, Okumura T, Motomura W, Takahashi N, KitagawaT, Kohgo Y

Dig Dis Sci   2000

Inhibition of food intake by intracisternal injection of anti-orexin antibody in fasted rats Reviewed

Yamada H, Okumura T, Motomura W, Kobayashi Y, Kohgo Y

Biochem Biophys Res Commun   2000

Activation of PPARgamma by troglitazone inhibits cell growth through the increase of p27Kip1 in human pancreatic carcinoma cells Reviewed

Motomura W, Okumura T, Takahashi N, Obara T, Kohgo Y

Cancer Res   2000

Stimulation of gastric acid secretion by centrally administered orexin-A in conscious rats Reviewed

Takahashi N, Okumura T, Yamada H, Kohgo Y

Biochem Biophys Res Commun   1999

Activation of PPARgamma inhibits cell growth and induces apoptosis in human gastric cancer cells Reviewed

Takahashi N, Okumura T, Motomura W, Fujimoto Y, Kawabata I, Kohgo Y

FEBS Lett   1999

An inverse correlation between serum leptin levels and HbA1c in patients with NIDDM Reviewed

Moriya M, Okumura T, Takahashi N, Yamagata K, Motomura W, Kohgo Y

Diabetes Res Clin Prac   1999

Delayed gastric emptying by Helicobacter pylori lipopolysacchride in concious rats Reviewed

Okumura T, Shoji E, Takahashi N, Wakebe H, Imagawa K, Kikuchi K, Kohgo Y

Dig Dis Sci   1998

Effect of submucosal administration of endothelin-3 on the rat gastric mucosa Reviewed

Watanabe Y, Okumura T,Harada K, Kohgo Y

J Gastroenterol   1997

Helocobacter pylori lipopolysacchride inhibits gastric acid secretion in pylorus-ligated conscious rats Reviewed

Ootsubo C, Okumura T, Takahashi N, Wakebe H, Imagawa K, Kikuchi K, Kohgo Y

Biochem Biophys Res Commun   1997

Gastric emptying in OLETF rats not expressing the CCK-A receptor gene Reviewed

Shoji E, Okumura T, Onodera S, Takahashi N, Harada K, Kohgo Y

Dig Dis Sci   1997

Intracisternal omkection of basic fibroblast growth factor reduces the severity of gastric mucosal lesions evoked by ethanol in rats Reviewed

Watanabe Y, Okumura T, Onodera S, Takahashi N, Shoji E, Kohgo Y

Jpn J Physiol   1997

Apolipoprotein A-IV acts in the brain to inhibit gastric emptying in the rat Reviewed

Okumura T, Fukagawa K, Tso P, Taylor IL, Pappas TN

Am J Physiol (Gastrointestinal and Liver Physiol)   1996

Susceptablity to the development of gastric ulceration in OLETF rats not expressing the CCK-A receptor gene Reviewed

Okumura T, Shoji E, Onodera S, Kohgo Y

Biochem Biophys Res Commun   1996

Intraduodenal lipid does not inhibit acid secretion in OLETF rats not expressing the CCK-A receptor gene Reviewed

Shoji E, Okumura T, Kohgo Y

Dig Dis Sci   1996

Microinjection of pancreatic polypeptide into the dorsal motor nucleus inhibits pancreatic secretion in rats Reviewed

Okumura T, Pappas TN, Taylor IL

Gastroenterology   1995

Mechanism of action of intracisternal apolipoprotein A-IV in inhibiting gastric acid secretion in rats Reviewed

Okumura T, Fukagawa K, Tso P, Taylor IL, Pappas TN

Gastroenterology   1995

Apolipoprotein A-IV acts centrally in the brain to reduce theseverity of gastric ulceration in the rat Reviewed

Okumura T, Taylor IL, Fukagawa K, Tso P, Pappas TN

Brain Res   1995

Intracisternal injection of TRH antibody blocks gastric emptying stimulation by 2^deoxy-D-glucose in rats Reviewed

Okumura T, Taylor IL, Ohning G, Tache Y, Pappas TN

Brain Res   1995

Gastric mucosal damage induced by 2-deoxy-D-glucose invloves ,edullary TRH in the rat Reviewed

Okumura T, Ohning G, Tache Y, Taylor IL, Pappas TN

Regul Pept   1995

Microinjection of TRH analogue into the dorsal vagal complex atimulates pancreatic secretion in rats Reviewed

Okumura T, Taylor IL, Pappas TN

Am J Physiol (Gastrointestinal and Liver Physiol)   1995

Site-specific formation of thyrotropin-releasing hormone-induced gastric ulcers through the vagal system Reviewed

Okumura T, Uehara A, Watanabe Y,Taniguchi Y, Kitamori S, Namiki M

Scand J Gastroenterol   1994

Intracisternal injection of apolipoprotein A-IV inhibits gastric secretion in pylorus-ligated conscious rats Reviewed

Okumura T, Fukagawa K, Tso P, Taylor IL, Pappas TN

Gastroenterology   1994

Intracisternal injection of pancreatic polypeptide stimulates gastric emptying in rats Reviewed

Okumura T, Pappas TN, Taylor IL

Neurosci Lett   1994

Stimulation of gastric secretion and enhanced gastric mucosal damage ifollowing central administration of pancreatic polypeptide (PP) in rats Reviewed

Okumura T, Pappas TN, Taylor IL

Dig Dis Sci   1994

Kainic acid injection into the medullary raphe produces gastric lesions through the vagal system in rats Reviewed

Okumura T, Uehara A, Taniguchi Y, Watanabe Y, Tsuji K, Kitamori S, Namiki M

Am J Physiol (Gastrointestinal and Liver Physiol)   1993

Gastric antisecretory and antiulcer actions of interleukin-1 Reviewed

Uehara A, Okumura T, Kitamori S, Shibata Y, Harada K, Takasugi Y, Namiki M

J Clin Gastroenterol   1992

Basic fibroblast growth factor (bFGF) acts centrally in the brain to inhibit gastric emptying in rats Reviewed

Okumura T, Uehara A, Kitamori S,Watanabe Y, Taniguchi Y, Tsuji K, Namiki M

Neurosci Lett   1992

Evidence that gastric antisecretory action of lipopolysacchride is not due to a toxic effect on gastric parietal cells Reviewed

Uehara A, Okumura T, Tsuji K, Taniguchi Y, Kitamori S Takasugi Y, Namiki M

Dig Dis Sci   1992

The gastric antisecretory action of lipopolysacchride is blocked by indomethacin Reviewed

Tsuji K, Uehara A, Okumura T, Taniguchi Y, Kitamori S, Takasugi Y, Namiki M

Eur J Pharmacol   1992

Central nervous system action of basic fibroblast growth factor : inhibition of gastric acid and pepsin secretion Reviewed

Okumura T, Uehara A, Tsuji K, Taniguchi Y, Kitamori S, Shibata Y, Okamura K, Takasugi Y, Namiki M

Biochem Biophys Res Commun   1991

Indomethacin reverses interleukin-1-induced hyperinsulinemia in conscious and freely moving rats Reviewed

Uehara A, Okumura T, Kumei Y, Takasugi Y, Namiki M

Eur J Pharmacol   1991

Central basic fibroblast growth factor inhibits gastric ulcer formation in rats Reviewed

Okumura T, Uehara A, Kitamori S, Takasugi Y, Namiki M

Biochem Biophys Res Commun   1991

Prevention by interleukin-1 of intracisternally injected thyrotropin-releasing hormone (TRH) induced gastric mucosal lesions in rats Reviewed

Okumura T, Uehara A, Kitamori S, Okamura K, Takasugi Y, Namiki M

Neurosci Lett   1991

Vagal motor neurons innervating the stomach are site-specifically organized in the dorsal motor nucleus of the vagus nerve in rats Reviewed

Okumura T Namiki M

J Auton Nerv Syst   1990

A cytokine that has potent gastric antisecretory and antiulcer actions via the central nervous system Reviewed

Uehara A, Okumura T, Kitamori S, Takasugi Y, Namiki M

Biochem Biophys Res Commun   1990

Regulation of food intake by interleukin-1 Reviewed

Uehara A, Okumura T, Kumei Y, Mutoh E, Takasugi Y, Namiki M

Int J Obest   1990

Lipopolysaccharide-induced inhibition of gastric acid and pepsin secretion in rats Reviewed

Uehara A, Okumura T, Okamura K, Takasugi Y, Namiki M

Eur J Pharmacol   1990

Inhibition of gastric pepsin secretion by peripherally or centrally injected interleukin-1 in rats Reviewed

Okumura T, Uehara A, Okamura K, Takasugi Y, Namiki M

Biochem Biophys Res Commun   1990

Site-specific formation of gastric ulcers by the electrical stimulation of the left or right gastric branch of the vagus nerve in the rat Reviewed

Okumura T, Uehara A, Okamura K, Namiki M

Scand J Gastroenterol   1990

Interleukin-1 inhibits the secretion of gastric acid in rats: possible involvement of prostaglandin Reviewed

Uehara A, Okumura T, Sekiya C, Okamura K, Takasugi Y, Namiki M

Biochem Biophys Res Commun   1989

Gastric lesions induced by kainic acid injection into the dorsal motor nucleus of the vagus nerve in rats Reviewed

Okumura T, Okamura K, Kitamori S, Hara H, Shibata Y, Namiki M

Scand J Gastroenterol   1989

Indomethacin blocks the anorexic action of interleukin-1 Reviewed

Uehara A, Ishikawa y, Okumura T, Okamura K, Sekiya C, Takasugi Y, Namiki M

Eur J Pharmacol   1989

脳内内因性orexin-Aは胃酸分泌の中枢性調節分子である．　消化管運動

奥村利勝．山田裕人（ Role： Joint author）

メディカルレビュー社  2005.4 

香辛料嗜好と胃痛胃疾患．総合臨床

奥村利勝（ Role： Sole author）

永井書店  2004.4 

心身症「日常病にどう対応しますか？」治療

奥村利勝（ Role： Sole author）

南山堂  2004.4 

糖・脂質代謝研究に有用なin vitro小腸モデルの構築と臓器間相互作用の解析

2010.4 - 2011.3

萌芽研究

ストレスキナーゼｐ３８ＭＡＰＫを介した抗癌剤耐性機構の解析と癌治療への応用

2008.4 - 2010.3

基盤研究(C)

中枢性迷走神経刺激による肝臓で発現する遺伝子発現変化の網羅的解析

2008.4 - 2009.3

挑戦的萌芽研究

肝脂肪過剰蓄積を中枢へ伝達する迷走神経求心路刺激調節機構の解明と治療への応用

2008.4 - 2009.3

挑戦的萌芽研究

大脳基底核による精神運動機能と自律神経機能の統合的制御

2007.4 - 2008.3

基盤研究(C)

適応的移動行動の発動と選択に関与する神経機構

2005.4 - 2009.3

特定領域研究