Details of a Researcher

* Japanese*

Name

FUNAKOSHI Hiroshi

Research areas, keyword

-Neuoscience, Neuroimmune system, Biochemistry, Regenerative Medicine, Genome Editing/Epigenome Editing, Orthopedic surgery

School Attended (except graduate school)

• Asahikawa Medical College , Faculty of Medicine

  1987.03 , Graduated

Graduate School Attended, etc.

• Asahikawa Medical College , Graduate School, Division of Medicine

  Doctor Course , 1991.06 , Completed

Degree

• Doctor (Medical Sciences) , Asahikawa Medical College , Degree Conferrer , 1991.06

Employment Record in Research

• Duty , Asahikawa Medical University School of Medicine Medical Course Basic Medicine Department of Advanced Medical Science , Professor , 2018.05 -

• Duty , Asahikawa Medical University Center for Advanced Research and Education , Professor and Director , 2011.09 - 2018.05

External Career

• Osaka University Graduate School of Medicine , Associate Professor , 2009.04 - 2011.01

• Osaka University Graduate School of Medicine , Associate Professor , 2007.04 - 2010.03

• Osaka University Graduate School of Medicine , Associate Professor , 2006.04 - 2007.03

• Osaka University Graduate School of Medicine , Associate Professor , 2002.08 - 2006.03

• Osaka University Graduate School of Medicine , Assistant Professor , 1995.10 - 2002.07

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Research Field (grants-in-aid-for-scientific-research classification)

• Molecular biology

• General medical chemistry

Research Achievement (Published Thesis)

• English: Funakoshi H, Okuno S and Fujisawa H, Different effects on activity caused by phosphorylation of tyrosine hydroxylase at serine 40 by three multifunctional protein kinases. , J Biol Chem , vol.266 (p.15614 - 15620) , 1991 , (IF:5.328)

• English: Funakoshi H, Frisen J, Barbany G, Timmusk T, Zachrisson O, Verge VM, and Persson H, Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve. , J Cell Biol , vol.123 (2) (p.455 - 465) , 1993 , (IF:9.575)

• English: Mudo G, Salin T, Condorelli DF, Jiang XH, Dell'Albani P, Timmusk T, Metsis M, Funakoshi H and Belluardo N, Increased expression of trkB and trkC messenger RNAs in the rat forebrain after focal mechanical injury. , Neuroscience , vol.57 (4) (p.901 - 912) , 1993 , (IF:3.292)

• English: Funakoshi H, Belluardo N, Arenas E, Yamamoto Y, Casabona A, Persson H and Ibanez CF, Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons. , Science , vol.268 (5216) (p.1495 - 1499) , 1995 , (IF:63.714)

• English: Ilag LL, Curtis R, Glass D, Funakoshi H, Tobkes NJ, Ryan TE, Acheson A, Lindsay RM, Persson H, Yancopoulos GD, DiStefano PS and Ibanez CF, Pan-neurotrophin 1: a genetically engineered neurotrophic factor displaying multiple specificities in peripheral neurons in vitro and in vivo. , Proc Natl Acad Sci U S A , vol.92 (2) (p.607 - 611) , 1995 , (IF:12.779)

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Research Achievement (Book)

• The Multiple Authorship :Recombinant human hepatocyte growth factor promotes functional recovery after spinal cord injury , Springer Japan , 2013 , Kitamura K, Iwanami A, Fujiyoshi K, Yamane J, Hikishima K, Funakoshi H, Nakamura T, Aoki M, Toyama Y, Okano H, Nakamura M

  The Book (the science book)

Research Achievement (Review)

• English: Molnarfi N, Benkhoucha M, Funakoshi H, Nakamura T, Lalive PH: , Hepatocyte growth factor: a regulator of inflammation and autoimmunity , Elsevier , Autoimmunity Reviews , vol.14 (4) (p.293 - 303) , 2015 , (IF:7.095)

• English: Matsumoto K, Funakoshi H, Takahashi H, and Sakai K, HGF-Met Pathway in Regeneration and Drug Discovery , MDPI AG (Basel, Switzerland) , Biomedicines (2) (p.275 - 300) , 2014 , (IF:4.7)

• English: Kitamura K, Iwanami A, Fujiyoshi K, Yamane J, Hikishima K, Funakoshi H, Nakamura T, Aoki M, Toyama Y, Okano H, Nakamura M. , Recombinant human hepatocyte growth factor promotes functional recovery after spinal cord injury , Publisher Springer Japan , Neuroprotection and Regeneration of the spinal cord (p.147 - 167) , 2014

• English: Funakoshi H, Nakamura T, Hepatocyte growth factor (HGF): Neurotrophic functions and therapeutic implications for neuronal injury/diseases , Bentham Science Publishers , Current Signal Transduction Therapy , vol.6 (2) (p.156 - 167) , 2011 , (IF:0.468)

• English: Funakoshi H, Kanai M, and Nakamura T, Modulation of tryptophan metabolism, promotion of neurogenesis and alteration of anxiety-related behavior in tryptophan 2,3-dioxygenase-deficient mice , Libertas Academica , International Journal of Tryptophan Research , vol.4 (p.7 - 18) , 2011 , (IF:4.4)

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Academic Awards Received

• Human Forntier Science Program (HFSP) long-term post-doctoral fellowship , 1993.12

• Swedish Research Council Guest Scientist fellowship , 1994.12

Industrial Property

• The Patent , METHODS OF TREATING AMYOTROPHIC LATERAL SCLEROSIS BY HGF , ToshikazuNakamura,Osaka(JP); Hiroshi Funakoshi,Osaka (JP); WoongSun,Seoul(KR)

  Patent application number ( 15/39,21 , 2017.01 ) Registration-of-patent number ( US10,058,590B2 , 2018.08 )

• The Patent , Remedies for amyotrophic lateral sclerosis , Hiroshi FunakoshiWoong SunToshikazu Nakamura

  Patent application number ( JP2000280081A , 2000.09 ) Registration-of-patent number ( CA2422774C , 2013.07 )

Updated on 2024/10/23

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