Updated on 2025/04/30

写真a

 
HAJIME Iwasaki
 
Organization
School of Medicine Medical Course Clinical Medicine Anesthesiology and Critical Care Medicine
External link

Degree

  • 博士(医学) ( 2015.9   旭川医科大学 )

Research Areas

  • Life Science / Anesthesiology

Education

  • 旭川医科大学 大学院   医学系研究科

    2010.4 - 2015.9

      More details

  • Saitama Medical University   医学部

    2001.4 - 2007.3

      More details

Research History

  • Asahikawa Medical College   Department of Anesthesiology & Critical Care Medicine   Associate Professor

    2023.10

      More details

  • Asahikawa Medical College   Lecturer

    2022.4 - 2023.9

      More details

  • 日本大学医学部   麻酔科学系麻酔科学分野   診療准教授

    2020.6 - 2022.3

      More details

  • 日本大学医学部   麻酔科学系麻酔科学分野   助教

    2020.4 - 2022.3

      More details

  • Shriners hospital for children, Massachusetts General Hospital   department of Anesthesiology   postdoctoral researcher

    2012.10 - 2014.3

      More details

  • Asahikawa Medical College   麻酔・蘇生学講座   Assistant Professor

    2012.4 - 2020.3

      More details

  • 旭川医科大学病院   麻酔科蘇生科   医員

    2010.4 - 2012.3

      More details

  • 埼玉医科大学総合医療センター   麻酔科   助教

    2009.4 - 2010.3

      More details

  • Saitama Medical University   総合臨床研修医

    2007.4 - 2009.3

      More details

▼display all

Professional Memberships

Committee Memberships

  •   日本麻酔科学会 国際交流委員会  

    2021.4 - 2023.3   

      More details

  •   日本麻酔科学会 英語ホームページリニューアル部会  

    2020.4 - 2021.3   

      More details

  • 日本麻酔科学会   英語ホームページリニューアル専門部会  

    2019.4 - 2021.3   

      More details

    Committee type:Academic society

    researchmap

Studying abroad experiences

  • 2012.10 - 2014.3   Massachusetts General Hospital, Harvard Medical School   postdoctoral fellow

Papers

  • Good clinical research practice (GCRP) in pharmacodynamic studies of neuromuscular blocking agents III: The 2023 Geneva revision Reviewed

    Thomas Fuchs-Buder, Sorin J. Brull, Malin Jonsson Fagerlund, J. Ross Renew, Guy Cammu, Glenn S. Murphy, Michiel Warlé, Matias Vested, Béla Fülesdi, Reka Nemes, Malachy O. Columb, Daniela Damian, Peter J. Davis, Hajime Iwasaki, Lars I. Eriksson

    Acta Anaesthesiologica Scandinavica   2023.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • A Comparison Between the Adductor Pollicis Muscle Using TOF-Watch SX and the Abductor Digiti Minimi Muscle Using TetraGraph in Rocuronium-Induced Neuromuscular Block: A Prospective Observational Study. Reviewed

    Iwasaki H., Yamamoto M., Sato H., Doshu-Kajiura A., Kitajima O., Takagi S., Luthe SK, Suzuki T.

    Anesthesia and Analgesia   135 ( 2 )   370 - 375   2022.8

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • Comparison of supramaximal currents obtained by acceleromyography and electromyography for monitoring the adductor pollicis muscle in pediatric patients. International journal

    Hajime Iwasaki, Kenichi Takahoko, Chihiro Yamagata, Yudai Nambu, Ayaka Suzuki, Yui Takada, Sarah Kyuragi Luthe, Hiroshi Makino

    Journal of clinical monitoring and computing   2025.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    The aim of this study was to compare the supramaximal currents obtained simultaneously by acceleromyography (AMG) TOF-Watch® SX and electromyography (EMG) AF-201P in pediatric patients. Patients aged 2-11 years who underwent elective surgery under general anesthesia were enrolled. AMG and EMG monitors were placed on opposite arms of the patient to stimulate the ulnar nerve and monitor the adductor pollicis muscles following the induction of general anesthesia. After the monitors were calibrated, rocuronium 0.6 mg/kg was administered. Endotracheal intubation was performed when the EMG showed a train-of-four (TOF) count of 0. The primary outcome was the supramaximal current set by each device's calibration. The secondary outcomes were the time from the administration of rocuronium to a TOF count of 0, the baseline and final TOF ratios, and the conditions surrounding intubation. The paired t test and the Wilcoxon signed-rank test were used to analyze parametric and nonparametric data. A P value < 0.05 indicated statistical significance. Clinical data from 25 pediatric patients were analyzed. The supramaximal current was significantly lower with EMG than with AMG (27.4 ± 6.1 vs. 54.2 ± 8.4 mA, p <.001). The time to a TOF count of 0 was significantly shorter with EMG than with AMG (58 [24-170] vs. 75 [26-236] seconds, p <.001). Both the baseline and final TOF ratios were significantly lower with EMG than with AMG. The ease of laryngoscopy was rated as excellent for all patients. The vocal cords were abducted in 76% of patients, and no movement to insertion of the endotracheal tube was confirmed in 96% of patients. We found that the supramaximal current was significantly lower with EMG than with AMG.

    DOI: 10.1007/s10877-025-01286-y

    PubMed

    researchmap

  • Laryngospasm Treated With Intramuscular Rocuronium in a Pediatric Patient Without Intravenous Access: A Case Report Reviewed

    Tabata H., Takahoko K., Luthe SK, Makino H., Iwasaki H.

    Cureus   16 ( 3 )   e56620   2024.3

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • The impact of electrosurgical devices on electromyography-based neuromuscular monitoring during abdominal laparotomy: a case series Reviewed

    Hajime Iwasaki, Kenichi Takahoko, Takuro Matsui, Yui Takada, Yukako Takahashi, Ami Sugawara, Atsushi Kurosawa

    Journal of clinical monitoring and computing   2023.5

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • Impact of intraoperative fluid restriction on renal outcomes in patients undergoing robotic-assisted laparoscopic prostatectomy Reviewed

    Chie Mori, Hajime Iwasaki, Izumi Sato, Kenichi Takahoko, Yosuke Inaba, Yohei Kawasaki, Gaku Tamaki, Hidehiro Kakizaki

    Journal of Robotic Surgery   2023.4

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • Fetal outcomes with and without the use of sugammadex in pregnant patients undergoing non-obstetric surgery: a multicenter retrospective study. Reviewed

    Noguchi S., Iwasaki H., Shiko Y., Kawasaki Y., Ishida Y., Shinomiya S., Ono Uokawa R., Mazda Y.

    International Journal of Obstetric Anesthesia   2023

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • Comparison of two electromyography-based neuromuscular monitors, AF-201P and TetraGraph, in rocuronium-induced neuromuscular block: A prospective comparative study Reviewed

    Hanae Sato, Hajime Iwasaki, Akira Doshu-Kajiura, Seidai Katagiri, Shunichi Takagi, Sarah Kyuragi Luthe, Takahiro Suzuki

    Anaesthesia Critical Care & Pain Medicine   41 ( 6 )   2022.12

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • A comparison between the adductor pollicis muscle and the abductor digiti minimi muscle using electromyography AF-201P in rocuronium-induced neuromuscular block: a prospective comparative study Reviewed

    Hajime Iwasaki, Hanae Sato, Shunichi Takagi, Osamu Kitajima, Sarah Kyuragi Luthe, Takahiro Suzuki

    BMC Anesthesiology   22 ( 1 )   117   2022.4

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • The Association Between Intraoperative Objective Neuromuscular Monitoring and Rocuronium Consumption During Laparoscopic Abdominal Surgery: A Single-Center Retrospective Analysis Reviewed International journal

    Takahoko K, Iwasaki H, Inaba Y, Matsuno T, Matsuno R, Luthe SK, Kanda H, Kawasaki Y.

    Cureus   13 ( 13 )   e19245   2021

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Background Rocuronium consumption with or without intraoperative objective neuromuscular monitoring in clinical settings of unrestricted use of sugammadex and neuromuscular monitoring has not been reported earlier. The study aimed to investigate the association between the use of intraoperative objective neuromuscular monitoring and rocuronium consumption in patients undergoing laparoscopic abdominal surgery. Methods Data were collected by reviewing electronic medical records of patients who received laparoscopic abdominal surgery under general anesthesia with rocuronium and reversal with sugammadex at a university teaching hospital between May 2017 and April 2018. A multivariate linear regression model was developed to compare the amount of rocuronium consumption (mg) per weight (kg) per hour (mg/kg/h) between the group in which intraoperative objective neuromuscular monitoring was used (NMM+ group) and the group in which intraoperative neuromuscular monitoring was not used (NMM- group). Additionally, we performed an interaction test. Results A total of 429 patients were evaluated, with 371 patients (86%) included in the NMM+ group and 58 patients (14%) in the NMM- group. Log-transformed rocuronium consumption between the NMM+ group and NMM- group was not significantly different (back-transformed β coefficients [95% CI]: 1.080 [0.951-1.226]; P = 0.23). Male sex and body mass index (BMI) were independent factors associated with 15% (0.853 [0.788-0.924]; P < 0.001) and 3% (for every 1 kg/m2 increase in BMI) (0.971 [0.963-0.979]; P < 0.001) decrease in intraoperative rocuronium consumption, respectively. A significant interaction was detected only between the use of neuromuscular monitoring and age ≥65 years (β: 0.803 [0.662-0.974]; P = 0.026). Conclusions Although the use of intraoperative objective neuromuscular monitoring was not an individual factor influencing intraoperative rocuronium consumption, this retrospective study demonstrated that the use of intraoperative neuromuscular monitoring reduced rocuronium consumption for approximately 20% of elderly patients (age ≥65 years) undergoing laparoscopic abdominal surgery.

    DOI: 10.7759/cureus.19245

    PubMed

    researchmap

  • Extravascular leakage of induction doses of rocuronium: four cases in which both depth of neuromuscular block and plasma concentration of rocuronium were assessed. Reviewed

    Takagi S, Kijima M, Iwasaki H, Doshu-Kajiura A, Kitajima O, Suzuki T.

    J Clin Monit Comput.   36 ( 2 )   587 - 592   2021

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Springer Science and Business Media LLC  

    DOI: 10.1007/s10877-021-00692-2

    researchmap

    Other Link: https://link.springer.com/article/10.1007/s10877-021-00692-2/fulltext.html

  • Plasma rocuronium concentration in cell salvage blood following cardiac surgery: a case series. Reviewed

    Iwasaki H, Takagi S, Kitajima O, Oshima Y, Luthe SK, Suzuki T.

    J Clin Monit Comput   2021

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • Comparison of Intrathecal Morphine With Continuous Patient-Controlled Epidural Anesthesia Versus Intrathecal Morphine Alone for Post-Cesarean Section Analgesia: A Randomized Controlled Trial Reviewed International journal

    Sato I, Iwasaki H, Luthe SK, Iida T, Kanda H.

    BMC Anesthesiology   20 ( 1 )   138   2020

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • Use of intraoperative neuromuscular monitor reduces the reversal dose of sugammadex: a single-center retrospective study. Reviewed International journal

    Iwasaki H, Kurosawa A, Iida T, Sasakawa T, Kanda H.

    Journal of Anesthesia   34 ( 2 )   276 - 280   2020

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • The Financial and Humanistic Costs Associated with Residual Neuromuscular Blockade Reviewed International journal

    Luthe SK, Iwasaki H.

    Current Anesthesiology Reports   2020

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • Quantitative Neuromuscular Monitoring: Current Devices, New Technological Advances, and Use in Clinical Practice Invited Reviewed International journal

    Iwasaki H, Nemes R, Brull SJ, Renew JR.

    Current Anesthesiology Reports   ( 8 )   134 - 144   2018

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • Preparing for the unexpected: special considerations and complications after sugammadex administration Reviewed International journal

    Iwasaki H, Renew JR, Kunisawa T, Brull SJ.

    BMC Anesthesiology   17 ( 1 )   140   2017.10

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12871-017-0429-9

    researchmap

  • The use of succinylcholine after sugammadex reversal Reviewed International journal

    Asakura C, Iwasaki H.

    Journal of Anesthesia   30 ( 5 )   915   2016

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • A case series of re-establishment of neuromuscular block with rocuronium after sugammadex reversal. Reviewed International journal

    Iwasaki H, Sasakawa T, Takahoko K, Takagi S, Nakatsuka H, Suzuki T, Iwasaki H.

    Journal of Anesthesia   30 ( 3 )   534 - 537   2016

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:[Springer Japan]  

    CiNii Books

    researchmap

  • Cannabinoid Receptor Type 1 Antagonist, AM251, Attenuates Mechanical Allodynia and Thermal Hyperalgesia after Burn Injury Reviewed

    Ueda M., Iwasaki H., Wang S., Murata E., Poon KY, Mao J., Martyn JA

    Anesthesiology   121 ( 6 )   1311 - 1319   2014

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • Unilateral hypoglossal nerve palsy after use of the laryngeal mask airway supreme. Case reports in anesthesiology Reviewed

    Takahoko K., Iwasaki H., Sasakawa T., Suzuki A., Matsumoto H., Iwasaki H.

    Case reports in anesthesiology   Epub   - 20140000   2014

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

  • Prediction of optimal reversal dose of sugammadex after rocuronium administration in adult surgical patients. Reviewed

    Otomo S., Iwasaki H., Takahoko K., Onodera Y., Sasakawa T., Kunisawa T., Iwasaki H.

    Anesthesiology research and practice   Epub   2014

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1155/2014/848051

    researchmap

  • Monitoring of neuromuscular blockade in one muscle group alone may not reflect recovery of total muscle function in patients with ocular myasthenia gravis Reviewed International journal

    Iwasaki H, Takahoko K, Otomo S, Sasakawa T, Kunisawa T, Iwasaki H.

    Canadian Journal of Anesthesia   60 ( 12 )   1222 - 1227   2013

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s12630-013-0042-4

    researchmap

  • Evaluation of neuromuscular blockade using TOF-Watch SX in type 2 diabetes patients Reviewed

    Iwasaki H., Takahoko K., Otomo S., Sasakawa T., Kunisawa T., Iwasaki H.

    麻酔   62 ( 8 )   929 - 934   2013

     More details

    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

    researchmap

  • A temporary decrease in twitch response following reversal of rocuronium-induced neuromuscular block with a small dose of sugammadex in a pediatric patient. Reviewed International journal

    Iwasaki H, Takahoko K, Otomo S, Sasakawa T, Kunisawa T, Iwasaki H

    Journal of Anesthesia   28 ( 2 )   288 - 290   2013

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

▼display all

Books

  • 麻酔科プラクティス8 麻酔管理の疑問に答える生理学

    岩崎 肇( Role: Joint author)

    文光堂  2023 

     More details

    Language:Japanese   Book type:Scholarly book

    researchmap

  • 胸部手術の麻酔

    岩崎肇( Role: Joint author)

    日本医事新報社  2021 

     More details

    Language:Japanese   Book type:Scholarly book

    researchmap

  • 新臨床麻酔スタンダード Ⅰ総論

    岩崎肇( Role: Joint author ,  Original_author: 岩崎肇 ,  筋弛緩モニター、 拮抗薬・回復薬)

    克誠堂出版  2020.5 

     More details

    Responsible for pages:156-159, 165-170   Language:Japanese   Book type:Scholarly book

    researchmap

  • 新臨床麻酔スタンダードⅠ総論

    岩崎肇( Role: Joint author)

    克誠堂出版  2020 

     More details

    Language:Japanese   Book type:Scholarly book

    researchmap

  • 一歩進んだ麻酔管理 ~常識は常に真実か?~

    岩崎肇( Role: Joint author ,  Original_author: 岩崎肇 ,  頭部挙上5秒で抜管!!, まだ先があるとは)

    克誠堂出版  2019 

     More details

    Responsible for pages:29-31, 34-36   Language:Japanese   Book type:Scholarly book

    researchmap

  • 麻酔科グリーンノート

    岩崎肇( Role: Compilator ,  Original_author: 岩崎肇)

    中外医学社  2018.5 

     More details

    Language:Japanese   Book type:Scholarly book

    researchmap

  • 麻酔科医として必ず知っておきたい周術期の循環管理

    岩崎肇( Role: Joint author ,  Original_author: 岩崎肇 ,  ロボット支援手術, INVOS5100C使用中のrSO2低下)

    羊土社  2016 

     More details

    Responsible for pages:293-295, 333-334   Language:Japanese   Book type:Scholarly book

    researchmap

  • 麻酔科医のための周術期の薬物使用法

    岩崎肇( Role: Joint author ,  Original_author: 岩崎肇 ,  ロクロニウム)

    中山書店  2015.5 

     More details

    Responsible for pages:100-101   Language:Japanese   Book type:Scholarly book

    researchmap

  • まれな疾患の麻酔 A to Z

    岩崎肇( Role: Sole author ,  Original_author: 岩崎肇 ,  副甲状腺機能低下症, エリス・ファン クレフェルト症候群)

    文光堂  2015.5 

     More details

    Responsible for pages:345, 654   Language:Japanese   Book type:Scholarly book

    researchmap

  • 麻酔の前に知っておきたい 手術手順と麻酔のコツ

    岩崎肇( Role: Sole author ,  Original_author: 岩崎肇 ,  筋弛緩モニターの豆知識, 精巣固定術,腎摘出術,副腎腫瘍摘出術,前立腺全摘術,膀胱全摘術)

    羊土社  2013.5 

     More details

    Responsible for pages:73, 184-193   Language:Japanese   Book type:Scholarly book

    researchmap

▼display all

Presentations

  • Electromyographic neuromuscular monitor International conference

    ICAPS2024 

     More details

    Event date: 2024.2

    Language:English   Presentation type:Oral presentation (invited, special)  

    researchmap

  • 五感を活かせない筋弛緩管理~筋弛緩薬の論理的使用~

    岩崎 肇

    日本麻酔科学会 関東甲信越・東京支部第63回合同学術集会 

     More details

    Event date: 2023.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    researchmap

  • 電位感知型筋弛緩モニタについて知っている事を全て教えます

    岩崎 肇

    日本麻酔科学会 関東甲信越・東京支部第63回合同学術集会 

     More details

    Event date: 2023.9

    Language:Japanese  

    researchmap

  • 筋弛緩モニター「使う」から「選んで使う」へ

    岩崎 肇

    日本麻酔科学会 第70回学術集会 

     More details

    Event date: 2023.6

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    researchmap

  • A new standard of neuromuscular monitoring.

    Hajime Iwasaki

    日本麻酔科学会 第70回学術集会 

     More details

    Event date: 2023.6

    Language:English   Presentation type:Symposium, workshop panel (nominated)  

    researchmap

  • 適切な筋弛緩モニタリング普及のためのハンズオンセミナー

    岩崎 肇

    日本臨床麻酔学会 第42回大会 

     More details

    Event date: 2022.11

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    researchmap

  • Current updates on electromyography-based neuromuscular monitoring

    岩崎 肇

    日本臨床麻酔学会 第42回大会 

     More details

    Event date: 2022.11

    Language:English   Presentation type:Oral presentation (general)  

    Venue:京都  

    researchmap

  • 加速度感知型筋弛緩モニタリングのコツ

    岩崎 肇

    日本臨床麻酔学会 第41回大会 

     More details

    Event date: 2021.11

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    researchmap

  • 電位感知型筋弛緩モニタの臨床使用

    岩崎 肇

    日本麻酔科学会 第68回学術集会 

     More details

    Event date: 2021.6

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    researchmap

  • TOF-Watch SXによる母指内転筋モニタリング

    岩崎 肇

    日本臨床麻酔学会 第39回大会 

     More details

    Event date: 2019.11

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    researchmap

▼display all

Research Projects

  • 小児の筋弛緩モニタリングにおける最大上刺激値の検討

    2023.5 - 2026.3

    日本光電工業株式会社 

      More details

  • 廃用性筋萎縮に対するα7アセチルコリン受容体刺激薬GTS-21の抑制効果の検討

    2020.4 - 2022.3

    若手研究

    岩崎肇

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3,900,000

    researchmap

  • α7アセチルコリン受容体が筋弛緩抵抗性に与える影響とその改善

    2015.4 - 2017.3

    若手研究(B)

    岩崎肇

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\2,730,000

    researchmap