記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:sec><jats:title/><jats:p> Although children with orofacial clefts have an increased risk for sleep-disordered breathing, no studies have examined the association of sleep duration. Thus, this study aimed to examine associations between orofacial clefts and sleep duration at 1 month, 6 months, 1 year, and 3 years of age in Japan. </jats:p></jats:sec><jats:sec><jats:title/><jats:p> A cohort study from the Japan Environment and Children's Study. </jats:p></jats:sec><jats:sec><jats:title/><jats:p> This study consisted of 91 497 children, including ones with isolated cleft lip and palate (n = 69), isolated cleft lip only (n = 48), and isolated cleft palate only (n = 37), for which recruitment was undertaken during 2011 to 2014. </jats:p></jats:sec><jats:sec><jats:title/><jats:p> Seep durations (hours per day) at 1 month, 6 months, 1 year, and 3 years of age, as reported by their mothers. </jats:p></jats:sec><jats:sec><jats:title/><jats:p> In the control group, mean sleep durations and standard deviations at 1 month, 6 months, 1 year, and 3 years of age were 15.2 (2.5), 13.6 (1.9), 12.9 (1.6), and 11.6 (1.2) h, respectively. Compared to the control group, linear regression models reported effect sizes and 95% confidence intervals shorter than 1 h for sleep duration of each type of isolated orofacial cleft at each time point. </jats:p></jats:sec><jats:sec><jats:title/><jats:p> This study suggested null associations between isolated orofacial clefts and sleep duration at 1 month, 6 months, 1 year, and 3 years of age. Children with isolated orofacial clefts had sufficient mean sleep duration. </jats:p></jats:sec>

DOI： 10.1177/10556656221128425

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1539/sangyoeisei.2023-033-e

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:title>Abstract</jats:title><jats:sec>
<jats:title>Background</jats:title>
<jats:p>Physicians in public health administration agencies (public health physicians: PHP) play important roles in public health; however, there are not enough such physicians in Japan. This study aimed to elucidate the factors related to the resignation and migration of PHPs using nationwide survey data.</jats:p>
</jats:sec><jats:sec>
<jats:title>Methods</jats:title>
<jats:p>Data from the Survey of Physicians, Dentists, and Pharmacists (2010, 2012, 2014, and 2016) were analyzed. The outcome was the resignation of PHPs or migration to public health administration agencies. The explanatory variables in the resignation analysis were age, sex, workplace, and board certification status. The type of work was added as an explanatory variable in the migration analysis, and clinical specialty was added to the clinical doctor-restricted analysis. The odds ratios (ORs) of the explanatory variables were calculated using generalized estimation equations.</jats:p>
</jats:sec><jats:sec>
<jats:title>Results</jats:title>
<jats:p>In the resignation analysis among PHPs, women had a significantly lower OR, whereas younger PHPs and those with board certifications had significantly higher ORs. In the migration to public health administration agencies analysis among medical doctors, women and those aged between 35 and 39 years had significantly higher ORs, but those with board certifications had significantly lower ORs. Hospital/clinic founders or directors had significantly lower ORs, but the clinic staff and ‘others/not working’ had significantly higher ORs. In the migration to public health administration agencies analysis among clinical physicians, those aged between 35 and 39 years had significantly higher ORs. Still, those with two or more board certifications had significantly lower ORs. Hospital/clinic founders or directors had significantly lower ORs, but the clinic staff had significantly higher ORs. Clinical doctors specializing in surgery and other specialties had significantly lower ORs, but those specializing in pediatrics and psychiatry/psychosomatic medicine had significantly higher ORs.</jats:p>
</jats:sec><jats:sec>
<jats:title>Conclusions</jats:title>
<jats:p>Having board certifications were significantly related to the resignation of PHPs and migration to public health administration agencies. Women migrated to public health administration agencies more than men and younger PHPs were more likely to resign. However, medical doctors aged between 35 and 39 years were more likely to migrate to public health administration agencies. Similarly, clinic staff, non-clinical physicians, and those whose specialties were pediatrics and psychiatry/psychosomatic medicine were more likely to migrate to public health administration agencies.</jats:p>
</jats:sec>

DOI： 10.1186/s12913-023-10085-7

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:sec id="sec001">
<jats:title>Background</jats:title>
<jats:p>The government of Japan has spent a significant amount on dental healthcare, but it remains unknown how the spending varies across age, type of service, and time. This study describes trends in dental expenditures in Japan.</jats:p>
</jats:sec>
<jats:sec id="sec002">
<jats:title>Methods</jats:title>
<jats:p>This descriptive study used two national data sources: Estimates of National Medical Care Expenditure and Survey on Economic Conditions in Health Care. We obtained annual total and average per capita dental expenditures by age in Japan from 1984 to 2020 and estimated the proportions of types of service from 1996 to 2021. All costs were adjusted for the 2020 Consumer Price Index (1 US dollar ≈ 100 yen in 2020).</jats:p>
</jats:sec>
<jats:sec id="sec003">
<jats:title>Results</jats:title>
<jats:p>Total dental expenditures increased from 1.96 trillion yen in 1984 to 3.00 trillion yen in 2020. In particular, total and average per capita dental spending for older persons showed a rapid increase (total: from 185 billion yen in 1984 to 1.18 trillion yen in 2020; average per capita: from 15,500 yen in 1984 to 32,800 yen in 2020), contributing to the total amount increase. The crown restoration and prosthesis category amounted to 50.3% of the total expenditure in 1996, and this proportion declined to 32.4% by 2021. In 0–14 years persons, expenses on the crown restoration and prosthesis category decreased while the medical management category (mainly including fees for a management plan for oral diseases or oral functions) increased. In persons aged 65 years or older, expenses on the crown restoration and prosthesis category decreased, with increasing expenses in the medical management and at-home treatment categories.</jats:p>
</jats:sec>
<jats:sec id="sec004">
<jats:title>Conclusion</jats:title>
<jats:p>The amount of dental spending in Japan substantially increased from 1.96 trillion yen in 1984 to 3.00 trillion yen in 2020), a 1.53-fold increase. The observed changes in annual dental spending varied across age groups and types of service.</jats:p>
</jats:sec>

DOI： 10.1371/journal.pone.0292547

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：{BMJ}  

<jats:sec><jats:title>Objectives</jats:title><jats:p>Multimorbidity is defined as the coexistence of two or more chronic physical or psychological conditions within an individual. The association between maternal multimorbidity and adverse perinatal outcomes such as preterm delivery and low birth weight has not been well studied. Therefore, this study aimed to investigate this association.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We conducted a prospective cohort study using data from the Japan Environment and Children’s Study of pregnant women between 2011 and 2014. Those with data on chronic maternal conditions were included in the study and categorised as having no chronic condition, one chronic condition or multimorbidities. The primary outcomes were the incidence of preterm birth (PTB), low birth weight (LBW) and small for gestational age (SGA). Adjusted logistic regression was performed to estimate ORs (aORs) and 95% CIs.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Of the 104 062 fetal records, 86 885 singleton pregnant women were analysed. The median maternal age and body mass index were 31 years and 20.5 kg/m<jats:sup>2</jats:sup>, respectively. The prevalence of pregnant women with one or more chronic conditions was 40.2%. The prevalence of maternal multimorbidity was 6.3%, and that of PTB, LBW, and SGA were 4.6%, 8.1%, and 7.5%, respectively. Pre-pregnancy underweight women were the most common, observed in 15.6% of multimorbidity cases, followed by domestic violence from intimate partner in 13.0%. Maternal multimorbidity was significantly associated with PTB (aOR 1.50; 95% CI 1.33–1.69), LBW (aOR 1.49; 95% CI 1.35–1.63) and SGA (aOR 1.33; 95% CI 1.20–1.46).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Maternal multimorbidity was associated with adverse perinatal outcomes, including PTB, LBW and SGA. The risk of adverse perinatal outcomes tends to increase with a rise in the number of chronic maternal conditions. Multimorbidity becomes more prevalent among pregnant women, making our findings important for preconception counselling.</jats:p></jats:sec>

DOI： 10.1136/bmjopen-2022-069281

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:title>Abstract</jats:title><jats:p>This study aimed to document the complication status of infants with orofacial clefts born between 2011 and 2014 in Japan. This was a descriptive study using data from the Japan Environment and Children's Study. Among 103 060 pregnancies, 248 infants with orofacial clefts were included (livebirth, 239; stillbirth, 4; miscarriage, 5). The items of interest were complication status of orofacial clefts: isolated (typical orofacial clefts only); multi‐malformed (orofacial clefts with unrelated major defects); syndromic (orofacial clefts with a syndrome or a chromosomal defect). Regarding the cleft subtypes, of 248 infants with orofacial clefts, 104 had cleft lip with cleft palate (CLP) (41.9%), 68 had cleft lip without cleft palate (CL) (27.4%), 58 had cleft palate without cleft lip (CP) (23.4%), and 18 were nonclassified (7.3%). In infants with CLP, the proportions of isolated, multi‐malformed, and syndromic phenotypes were 73.1%, 15.4%, and 11.5%, respectively. In infants with CL, the proportions were 79.4%, 16.2%, and 4.4%, respectively. In infants with CP, the proportions were 69.0%, 13.8%, and 17.2%, respectively. The most frequently associated congenital anomaly was congenital heart disease. In infants with syndromic CLP, 41.7% had trisomy 13. In infants with syndromic CP, 80.0% had the Pierre Robin sequence. Congenital heart disease could be the most frequently associated congenital anomaly. The most frequently associated syndrome could be trisomy 13 in those with CLP and Pierre Robin sequence in those with CP.</jats:p>

DOI： 10.1111/cga.12496

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:title>Abstract</jats:title><jats:sec id="S1935789322002452_as1"><jats:title>Objective:</jats:title><jats:p>This cross-sectional study aimed to examine factors potentially associated with psychological distress among undergraduate students during the coronavirus disease 2019 pandemic in Japan.</jats:p></jats:sec><jats:sec id="S1935789322002452_as2"><jats:title>Methods:</jats:title><jats:p>We analyzed data of 958 undergraduates (median age 20 y; 56.8% women) from a Web-based, self-administered questionnaire survey conducted from August to September 2020. Prevalence ratios (PRs) for psychological distress defined as 5 points or over of the Kessler Psychological Distress Scale (K6) were calculated by Poisson regression models.</jats:p></jats:sec><jats:sec id="S1935789322002452_as3"><jats:title>Results:</jats:title><jats:p>The proportion of psychological distress was 40.0%. In the mutually-adjusted model, the following were significantly associated with psychological distress: decreases in household income to 50-99% of the prepandemic amount compared with no change (PR = 1.48), newly experiencing unpaid wages compared with no experience (PR = 1.44), insufficient money to buy necessities compared with no shortage (PR = 1.45), receiving a student loan or scholarship compared with none (PR = 1.27), and communication 1 to 3 times a month compared with at least once a week (PR = 1.22). In contrast, school closure during the pandemic compared with no closure was inversely associated with psychological distress (PR = 0.78).</jats:p></jats:sec><jats:sec id="S1935789322002452_as4"><jats:title>Conclusions:</jats:title><jats:p>Among undergraduate students in Japan, economic difficulties significantly predicted psychological distress.</jats:p></jats:sec>

DOI： 10.1017/dmp.2022.245

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1265/ehpm.22-00169

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.envres.2022.114302

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:title>Abstract</jats:title><jats:sec>
<jats:title>Background</jats:title>
<jats:p>The extremes of maternal pre-pregnancy body mass index (BMI) are known to be risk factors associated with obstetric and adverse perinatal outcomes. Among Japanese women aged 20 years or older, the prevalence of underweight (BMI &lt; 18.5 kg/m<jats:sup>2</jats:sup>) was 11.5% in 2019. Maternal thinness is a health problem caused by the desire to become slim. This study aimed to investigate the association between the severity of maternal low pre-pregnancy BMI and adverse perinatal outcomes, including preterm birth (PTB), low birth weight (LBW), and small-for-gestational age (SGA).</jats:p>
</jats:sec><jats:sec>
<jats:title>Methods</jats:title>
<jats:p>We conducted a prospective cohort study using data from the Japan Environment and Children’s Study, which recruited pregnant individuals between 2011 and 2014. Pre-pregnancy BMI was categorized as severe-moderate underweight (BMI <jats:underline>&lt;</jats:underline> 16.9 kg/m<jats:sup>2</jats:sup>), mild underweight (BMI, 17.0–18.4 kg/m<jats:sup>2</jats:sup>), low-normal weight (BMI, 18.5–19.9 kg/m<jats:sup>2</jats:sup>), high-normal weight (BMI, 20.0–22.9 kg/m<jats:sup>2</jats:sup>), overweight (BMI, 23.0–24.9 kg/m<jats:sup>2</jats:sup>), and obese (BMI ≥ 25.0 kg/m<jats:sup>2</jats:sup>). The high-normal weight group was used as the reference for statistical analyses. Adjusted logistic regression was performed to evaluate the association between pre-pregnancy BMI and PTB, LBW, and SGA.</jats:p>
</jats:sec><jats:sec>
<jats:title>Results</jats:title>
<jats:p>Of 92,260 singleton pregnant individuals, the prevalence was 2.7% for severe-moderate underweight, 12.9% for mild underweight, and 24.5% for low-normal weight. The prevalence of adverse outcomes was 4.6% for PTB, 8.1% for LBW, and 7.6% for SGA. The adjusted odds ratios (aORs) for PTB were 1.72 (95% confidence interval [CI], 1.46–2.03) for severe-moderate underweight and 1.26 (95% CI, 1.14–1.39) for mild underweight. The aORs of LBW were 2.55 (95% CI, 2.27–2.86) for severe-moderate underweight, 1.64 (95% CI, 1.53–1.76) for mild underweight, and 1.23 (95% CI, 1.16–1.31) for low-normal weight. The aORs of SGA were 2.53 (95% CI, 2.25–2.84) for severe-moderate underweight, 1.66 (95% CI, 1.55–1.79) for mild underweight, and 1.29 (95% CI, 1.21–1.38) for low-normal weight.</jats:p>
</jats:sec><jats:sec>
<jats:title>Conclusions</jats:title>
<jats:p>A dose-response relationship was found between the severity of low pre-pregnancy BMI and PTB, LBW, and SGA. Even low-normal BMI (18.5–19.9 kg/m<jats:sup>2</jats:sup>) increased the risk of LBW and SGA. This study provides useful information for pre-conception counseling in lean individuals.</jats:p>
</jats:sec>

DOI： 10.1186/s12884-022-04418-3

researchmap

DOI： 10.51094/jxiv.111

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:sec><jats:title>Objective</jats:title><jats:p>Previous studies have indicated that spatial variation in suicide mortality is associated with area-specific socioeconomic characteristics, such as socioeconomic deprivation and social fragmentation. However, most of these studies have been conducted in the West and findings from Asian countries are limited. This study aims to investigate associations between socioeconomic characteristics and suicide mortality rates across 1887 municipalities in Japan between 2009 and 2017. We also assessed these associations by gender and age group.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Suicide data were obtained from the suicide statistics of the Ministry of Health, Labour and Welfare in Japan and included information on the number of suicides by gender, age and municipality location. Social fragmentation, socioeconomic deprivation and urbanicity were used as socioeconomic characteristics in this study and were created from survey data obtained from the 2010 census. Bayesian hierarchical models were used to examine associations between socioeconomic characteristics and suicide risk.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Suicide rates were significantly higher in municipalities with higher levels of deprivation, with a rate ratio of 1.13 (95% credible interval: 1.10 to 1.17) in the highest quartile compared with the lowest. Higher levels of urbanicity had significantly lower suicide rates, with a rate ratio of 0.79 (95% credible interval: 0.77 to 0.82) in the highest quartile compared with the lowest. However, associations between exposures and suicide varied considerably by gender and age. Among both men and women aged 0–39 years, fragmentation was significantly associated with suicide, with rate ratios of 1.07 and 1.15 for men and women, respectively, in the highest quartile compared with the lowest.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Suicide prevention in Japan should particularly focus on areas with high levels of deprivation or low levels of urbanicity. Furthermore, young Japanese people residing in the most fragmented municipalities were also at high risk of suicide, and appropriate measures need to be taken.</jats:p></jats:sec>

DOI： 10.1136/bmjopen-2022-063255

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:sec>
<jats:title>Background</jats:title>
<jats:p>Psychological stress is a potential risk factor for oral diseases. However, evidence for the association between work stress and oral diseases is scarce. We aimed to examine the associations of work stress, according to the effort-reward imbalance model, with dental caries, periodontal status, and tooth loss.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Methods</jats:title>
<jats:p>This cross-sectional study included 184 regular employees at a medical university and 435 registrants of a web research company. Work stress was assessed using the effort-reward imbalance (ERI) ratio. Dental caries and tooth loss were assessed according to the number of decayed, filled, and missing teeth (DMFT) among the set of 28 teeth. Periodontal status was assessed using a self-administered questionnaire. For the DMFT, a linear regression model was used to estimate the unstandardised coefficients. A Poisson regression model was used to estimate the prevalence ratios (PRs) of poor periodontal status.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Results</jats:title>
<jats:p>Among medical university employees and employees enrolled from among the registrants of an online research company, a one-unit increase in the ERI ratio was associated with −2.81 (95% CI [−4.70 to −0.92]; <jats:italic>p</jats:italic>-value = 0.004) and −0.84 (95% CI [−1.80 to 0.12]; <jats:italic>p</jats:italic>-value = 0.085) changes in the DMFT from adjusted linear regression models, respectively. In employees enrolled from among the registrants of an online research company, a one-unit increase in the ERI ratio was also associated with 1.55 (95% CI [1.04–2.32]; <jats:italic>p</jats:italic>-value = 0.032) of the PR for poor periodontal status based on Poisson regression models.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Conclusion</jats:title>
<jats:p>ERI at work was associated with an increased risk of poor periodontal status.</jats:p>
</jats:sec>

DOI： 10.7717/peerj.13792

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.lanwpc.2022.100480

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.2188/jea.je20200438

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.2486/indhealth.2021-0274

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1111/ina.12931

researchmap

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:title>Abstract</jats:title><jats:sec>
<jats:title>Background</jats:title>
<jats:p>The influence of maternal psychological distress on infant congenital heart defects (CHDs) has not been thoroughly investigated. Furthermore, there have been no reports on the combined effect of maternal psychological distress and socioeconomic status on infant CHDs. This study aimed to examine whether maternal psychological distress, socioeconomic status, and their combinations were associated with CHD.</jats:p>
</jats:sec><jats:sec>
<jats:title>Methods</jats:title>
<jats:p>We conducted a prospective cohort study using data from the Japan Environment and Children’s Study, which recruited pregnant women between 2011 and 2014. Maternal psychological distress was evaluated using the Kessler Psychological Distress Scale in the first trimester, while maternal education and household income were evaluated in the second and third trimesters. The outcome of infant CHD was determined using the medical records at 1 month of age and/or at birth. Crude- and confounder-adjusted logistic regression analyses were performed to evaluate the association between maternal psychological distress and education and household income on infant CHD.</jats:p>
</jats:sec><jats:sec>
<jats:title>Results</jats:title>
<jats:p>A total of 93,643 pairs of mothers and infants were analyzed, with 1.1% of infants having CHDs. Maternal psychological distress had a significantly higher odds ratio in the crude analysis but not in the adjusted analysis, while maternal education and household income were statistically insignificant. In the analysis of the combination variable of lowest education and psychological distress, the P for trend was statistically significant in the crude and multivariate model excluding anti-depressant medication, but the significance disappeared in the full model (P = 0.050).</jats:p>
</jats:sec><jats:sec>
<jats:title>Conclusions</jats:title>
<jats:p>The combination of maternal psychological distress and lower education may be a possible indicator of infant CHD.</jats:p>
</jats:sec>

DOI： 10.1186/s12884-021-04001-2

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:p>Pets may play a role in the social-emotional development of children. In particular, some studies have suggested that family dog ownership is associated with better health outcomes. To date, no study has assessed child development in association with dog ownership of different time points. The purpose of the current study was primary to investigate whether “ever” family dog ownership was associated with early child development, and secondary to further examine whether associations between family dog ownership and early child development differ among family dog ownership of status, including “past only”, “current only”, and “always” groups, using the data of family dog ownership obtained at multiple time points. Associations between family dog ownership and infant development at 3 years of age were examined using data from a nationwide prospective birth cohort study, the Japan Environment and Children’s Study (n = 78,941). “Ever” family dog ownership was categorized to “past only”, “current only”, and “always”. We observed that children with “ever” family dog ownership showed a significantly decreased risk of developmental delay in the communication (odds ratio [OR] = 0.87; 95% confidence interval [CI]: 0.78, 0.96), gross motor (OR = 0.83; 95% CI: 0.76, 0.92), problem-solving (OR = 0.89; 95% CI: 0.83, 0.96) and personal-social (OR = 0.86; 95% CI: 0.72, 0.92) domains compared to children with “never” family dog ownership. Furthermore, a significantly decreased risk of developmental delay in gross motor function was observed in association with living with dogs in the “past only” (OR = 0.83; 95% CI: 0.73, 0.95) and “always” (OR = 0.86; 95% CI: 0.75, 0.98). In addition, a decreased risk of developmental delay in the problem-solving domain was associated with “past” family dog ownership (OR = 0.87; 95% CI: 0.79, 0.97) and in the personal-social domain was associated with “always” family dog ownership (OR = 0.81; 95% CI = 0.68, 0.95). Given the possible positive association between early life child development and family dog ownership, living with dogs may be an important factor to be considered when assessing child development.</jats:p>

DOI： 10.3390/ijerph18137082

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:title>Abstract</jats:title><jats:sec>
<jats:title>Purpose</jats:title>
<jats:p>There are notable geographic variations in incidence rates of suicide both in Japan and globally. Previous studies have found that rurality/urbanity shapes intra-regional differences in suicide mortality, and suicide risk associated with rurality can vary significantly by gender and age. This study aimed to examine spatial patterning of and rural–urban differences in suicide mortality by gender and age group across 1887 municipalities in Japan between 2009 and 2017.</jats:p>
</jats:sec><jats:sec>
<jats:title>Methods</jats:title>
<jats:p>Suicide data were obtained from suicide statistics of the Ministry of Health, Labour and Welfare in Japan. We estimated smoothed standardized mortality ratios for suicide for each of the municipalities and investigated associations with level of rurality/urbanity using Bayesian hierarchical models before and after adjusting for socioeconomic characteristics.</jats:p>
</jats:sec><jats:sec>
<jats:title>Results</jats:title>
<jats:p>The results of the multivariate analyses showed that, for males aged 0–39 and 40–59 years, rural residents tended to have a higher suicide risk compared to urban ones. For males aged 60+ years, a distinct rural–urban gradient in suicide risk was not observed. For females aged 0–39 years, a significant association between suicide risk and rurality was not observed, while for females aged 40–59 years and females aged 60 years or above, the association was a U-shaped curve.</jats:p>
</jats:sec><jats:sec>
<jats:title>Conclusion</jats:title>
<jats:p>Our results showed that geographical distribution of and rural–urban differences in suicide mortality in Japan differed substantially by gender and age. These findings suggest that it is important to take demographic factors into consideration when municipalities allocate resources for suicide prevention.</jats:p>
</jats:sec>

DOI： 10.1007/s00127-020-01978-7

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:sec><jats:title>Objectives</jats:title><jats:p>Although psychological stress is a risk factor for oral diseases, there seems to be no review on work stress. This study aimed to review the evidence on the association between work stress and oral conditions, including dental caries, periodontal status and tooth loss.</jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p>A systematic review of published observational studies.</jats:p></jats:sec><jats:sec><jats:title>Data sources</jats:title><jats:p>A systematic literature search was conducted in PubMed and Scopus databases on 12 August 2020.</jats:p></jats:sec><jats:sec><jats:title>Study selection</jats:title><jats:p>Articles were screened based on the following inclusion criteria: published after 1966; in English only; epidemiological studies on humans (except case studies, reviews, letters, commentaries and editorials); and examined the association of work stress with dental caries, periodontal status and tooth loss.</jats:p></jats:sec><jats:sec><jats:title>Data extraction</jats:title><jats:p>Data were extracted from eligible studies. A quality assessment was conducted using the Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Of 402 articles identified, 11 met the inclusion criteria, and 1 study assessed the association of work stress with dental caries and periodontal status. Of 11 studies, 1 reported a non-significant association between work stress and dental caries; 8 of 9 studies reported a significant association between work stress and worse periodontal status; and 1 of 2 studies reported a significant association between work stress and tooth loss. Nine of 11 studies were cross-sectional, while the remaining 2 studies had unclear methodology. Only two studies were sufficiently adjusted for potential confounders. Eight studies assessed work stress but did not use the current major measures. Three studies were rated as fair, while eight studies had poor quality.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>There is a lack of evidence on the association of work stress with dental caries and tooth loss. Eight studies suggested potential associations between periodontal status and work stress. Cohort studies using the major work stress measures and adjusting for the potential confounders are needed.</jats:p></jats:sec>

DOI： 10.1136/bmjopen-2020-046532

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:sec id="sec001">
<jats:title>Background</jats:title>
<jats:p>The influence of mothers’ and fathers’ educational levels in separate evaluations of asthma has not been fully investigated. This study aims to examine the associations of the mother’s and fathers’ educational levels with childhood wheeze and asthma adjusting for crude and pre-and post-natal modifiable risk factors.</jats:p>
</jats:sec>
<jats:sec id="sec002">
<jats:title>Methods</jats:title>
<jats:p>We conducted a prospective cohort study using data from the Japan Environment and Children’s Study, which recruited pregnant women from 2011 to 2014. The mother’s and father’s educational levels were surveyed by a questionnaire during the pregnancy, and childhood wheezing and doctor-diagnosed asthma were estimated using a 3-year questionnaire. Multilevel logistic regression analysis was performed to evaluate the association between the mother’s and father’s educational levels and childhood wheezing and asthma, adjusted for pre-and post-natal factors.</jats:p>
</jats:sec>
<jats:sec id="sec003">
<jats:title>Results</jats:title>
<jats:p>A total of 69,607 pairs of parents and their single infants were analyzed. We found 17.3% of children had wheezing and 7.7% had asthma. In crude analyses, lower educational level of parents was associated with an increased risk of childhood wheezing and asthma. After full adjustment, a lower educational level of mothers was associated with an increased risk of childhood asthma (junior high school (reference: high school); odds ratio (OR): 1.17, 95% CI, 1.01–1.36), and higher educational level, especially the mother’s, was associated with an increased risk of childhood wheezing (technical junior college, technical/vocational college, or associate degree (ECD3); OR: 1.12, 95% CI, 1.06–1.18, bachelor’s degree, or postgraduate degree; OR: 1.10, 95% CI, 1.03–1.18), and asthma (ECD3; OR: 1.13, 95% CI, 1.04–1.21).</jats:p>
</jats:sec>
<jats:sec id="sec004">
<jats:title>Conclusions</jats:title>
<jats:p>Parents’ lower educational level was a crude risk factor for childhood wheezing and asthma. However, an increased risk of wheezing due to mothers’ higher educational level was found after adjusting for pre-and post-natal factors.</jats:p>
</jats:sec>

DOI： 10.1371/journal.pone.0250255

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.2188/jea.je20190347

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:sec><jats:title>Objective:</jats:title><jats:p>This study examined psychological status trajectories of mothers of infants with nonsyndromic orofacial clefts in Japan.</jats:p></jats:sec><jats:sec><jats:title>Design:</jats:title><jats:p>Prospective cohort study.</jats:p></jats:sec><jats:sec><jats:title>Setting:</jats:title><jats:p>Data from the Japan Environment and Children’s Study.</jats:p></jats:sec><jats:sec><jats:title>Participants:</jats:title><jats:p>Infants with a nonsyndromic cleft (N = 148) including cleft lip and palate (CLP; n = 72), cleft lip (CL; n = 46), and cleft palate (CP; n = 30). The control group included unaffected infants (N = 84 454).</jats:p></jats:sec><jats:sec><jats:title>Main Outcome Measures:</jats:title><jats:p>At 15 weeks and 27 weeks of pregnancy and 12 months after birth, the Kessler Psychological Distress Scale (clinical cutoff ≥5) was used. At 1 month and 6 months after birth, the Edinburgh Postnatal Depression Scale (clinical cutoff ≥9) was used.</jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p>Prenatal diagnosis rates were unavailable. Mothers of infants with CLP had higher psychological distress than controls at 27 weeks of pregnancy (prevalence ratio [PR] = 1.36, 95% CI: 1.06-1.74) and postnatal depression at 1 month after birth (PR = 2.21, 95% CI: 1.53-3.19). Mothers of infants with CP showed heightened psychological distress at 27 weeks of pregnancy (PR = 1.62, 95% CI: 1.21-2.17) and postnatal depression 6 months after birth (PR = 1.86, 95% CI: 1.01-3.43). There was no significant association between CL and maternal psychological status. At 12 months after birth, no differences in distress were found between mothers of infants with a cleft and controls.</jats:p></jats:sec><jats:sec><jats:title>Conclusions:</jats:title><jats:p>Mothers of infants with orofacial clefts may need psychosocial support, particularly during pregnancy and the first year after birth.</jats:p></jats:sec>

DOI： 10.1177/1055665620951399

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.2188/jea.je20190057

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.waojou.2020.100128

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.2486/indhealth.2018-0226

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1620/tjem.251.217

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1038/s41440-019-0299-2

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.2188/jea.je20180080

researchmap

掲載種別：研究論文（学術雑誌）  

This study aimed to construct a childhood obesity risk index based on predictors identified in pregnant women and 1-yr-old infants. The primary outcome was an identified obesity index of > 20% at 6-8 yr of age. Of a total sample size of 6,846 mother-child pairs, 80% and 20% were randomly allocated to the derivation and validation cohorts, respectively. For the derivation cohort, univariate and multivariate logistic regression analyses of data were conducted to identify the final predictors to determine the childhood obesity risk score algorithm. These included pre-pregnancy body mass index (BMI), child's gender, smoking during pregnancy, education, and obesity index at one yr of age. The β coefficients for categories of predictor variables were each divided by the smallest value among them. The quotient was rounded off to the integer and assigned to the risk score, and a value of zero was assigned to reference categories. A total risk score was calculated for each individual. A cutoff point ≥ 16 had 22.2% and 21.8% positive predictive values in the derivation and validation cohorts, respectively. In conclusion, the childhood obesity risk score algorithm was constructed based on generic predictors that can be easily obtained from maternal and child health handbooks.

DOI： 10.1297/cpe.28.81

PubMed

researchmap

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.11260/kenkokyoiku.27.143

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.2188/jea.je20170330

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1186/s12903-018-0488-4

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.sleep.2018.07.020

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.socscimed.2018.02.015

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1093/aje/kwx274

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.2188/jea.je20160184

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:title>Abstract</jats:title><jats:p>The Japan Gerontological Evaluation Study is a nationwide cohort study of individuals aged 65 years and older established in July 2010. Seven months later, one of the study field sites was directly in the line of the 2011 Great East Japan Earthquake and Tsunami. Despite the 1-hour warning interval between the earthquake and tsunami, many coastal residents lost their lives. We analyzed the risk of all-cause mortality on the day of the disaster as well as in the 38-month interval after the disaster. Among 860 participants, 33 (3.8%) died directly because of the tsunami and an additional 95 people died during the 38-month follow-up period. Individuals with depressive symptoms had elevated risk of mortality on the day of the disaster (odds ratio = 3.90 [95% CI: 1.13, 13.47]). More socially connected people also suffered increased risk of mortality, although these estimates were not statistically significant. In contrast, after the disaster, frequent social interactions reverted back to predicting improved survival (hazard ratio = 0.46 (95% CI: 0.26, 0.82)). Depressive symptoms and stronger social connectedness were associated with increased risk of mortality on the day of the disaster. After the disaster, social interactions were linked to improved survival.</jats:p>

DOI： 10.1038/s41598-017-16636-3

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:p> This study examined whether the number of teeth contributes to the compression of morbidity, measured as a shortening of life expectancy with disability, an extension of healthy life expectancy, and overall life expectancy. A prospective cohort study was conducted. A self-reported baseline survey was given to 126,438 community-dwelling older people aged ≥65 y in Japan in 2010, and 85,161 (67.4%) responded. The onset of functional disability and all-cause mortality were followed up for 1,374 d (follow-up rate = 96.1%). A sex-stratified illness-death model was applied to estimate the adjusted hazard ratios (HRs) for 3 health transitions (healthy to dead, healthy to disabled, and disabled to dead). Absolute differences in life expectancy, healthy life expectancy, and life expectancy with disability according to the number of teeth were also estimated. Age, denture use, socioeconomic status, health status, and health behavior were adjusted. Compared with the edentulous participants, participants with ≥20 teeth had lower risks of transitioning from healthy to dead (adjusted HR, 0.58 [95% confidence interval (CI), 0.50–0.68] for men and 0.70 [95% CI, 0.57–0.85] for women) and from healthy to disabled (adjusted HR, 0.52 [95% CI, 0.44–0.61] for men and 0.58 [95% CI, 0.49–0.68] for women). They also transitioned from disabled to dead earlier (adjusted HR, 1.26 [95% CI, 0.99–1.60] for men and 2.42 [95% CI, 1.72–3.38] for women). Among the participants aged ≥85 y, those with ≥20 teeth had a longer life expectancy (men: +57 d; women: +15 d) and healthy life expectancy (men: +92 d; women: +70 d) and a shorter life expectancy with disability (men: –35 d; women: –55 d) compared with the edentulous participants. Similar associations were observed among the younger participants and those with 1 to 9 or 10 to 19 teeth. The presence of remaining teeth was associated with a significant compression of morbidity: older Japanese adults’ life expectancy with disability was compressed by 35 to 55 d within the follow-up of 1,374 d. </jats:p>

DOI： 10.1177/0022034517713166

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:sec><jats:title>Objectives</jats:title><jats:p>Survivors of the 2011 Great East Japan Earthquake have an increased risk of depressive symptoms. We sought to examine whether participation in group exercise and regular walking could mitigate the worsening of depressive symptoms among older survivors.</jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p>Prospective observational study.</jats:p></jats:sec><jats:sec><jats:title>Setting</jats:title><jats:p>Our baseline survey was conducted in August 2010, ∼7 months prior to the Great East Japan Earthquake and tsunami, among people aged 65 or older residing in Iwanuma City, Japan, which suffered significant damage in the disaster. A 3-year follow-up survey was conducted in 2013.</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>3567 older survivors responded to the questionnaires predisaster and postdisaster.</jats:p></jats:sec><jats:sec><jats:title>Primary outcome measures</jats:title><jats:p>Change in depressive symptoms was assessed using the 15-item Geriatric Depression Scale (GDS).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>From predisaster to postdisaster, the mean change in GDS score increased by 0.1 point (95% CI −0.003 to 0.207). During the same interval, the frequency of group exercise participation and daily walking time also increased by 1.9 days/year and 1.3 min/day, respectively. After adjusting for all covariates, including personal experiences of disaster, we found that increases in the frequency of group exercise participation (<jats:italic>B</jats:italic>=−0.139,<jats:italic>β</jats:italic>=−0.049, p=0.003) and daily walking time (<jats:italic>B</jats:italic>=−0.087,<jats:italic>β</jats:italic>=−0.034, p=0.054) were associated with lower GDS scores. Interactions between housing damage and changes in group exercise participation (<jats:italic>B</jats:italic>=0.103,<jats:italic>β</jats:italic>=0.034, p=0.063) and changes in walking habit (<jats:italic>B</jats:italic>=0.095,<jats:italic>β</jats:italic>=0.033, p=0.070) were marginally significant, meaning that the protective effects tended to be attenuated among survivors reporting more extensive housing damage.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Participation in group exercises or regular walking may mitigate the worsening of depressive symptoms among older survivors who have experienced natural disaster.</jats:p></jats:sec>

DOI： 10.1136/bmjopen-2016-013706

researchmap

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.5834/jdh.67.4_270

researchmap

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.5834/jdh.67.3_160

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:sec><jats:title>Objectives</jats:title><jats:p>To describe associations between tooth loss and changes in higher‐level functional capacity.</jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p>Prospective cohort study.</jats:p></jats:sec><jats:sec><jats:title>Setting</jats:title><jats:p>Twenty‐four Japanese municipalities between 2010 and 2013.</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>Functionally independent community‐dwelling persons aged 65 and older (N = 62,333).</jats:p></jats:sec><jats:sec><jats:title>Measurements</jats:title><jats:p>Self‐reported number of teeth was used as an exposure variable. The outcome was changes in higher‐level functional capacity measured using the Tokyo Metropolitan Institute of Gerontology Index of Competence (<jats:styled-content style="fixed-case">TMIG</jats:styled-content>‐<jats:styled-content style="fixed-case">IC</jats:styled-content>), which consists of three domains: instrumental activities of daily living, intellectual activity, and social roles. The <jats:styled-content style="fixed-case">TMIG</jats:styled-content>‐<jats:styled-content style="fixed-case">IC</jats:styled-content> score ranges from 0 (lowest function) to 13 (highest function). All covariates were chosen from baseline demographic, socioeconomic, health behavior, and health variables based upon evidence from previous studies. Inverse‐probability weighting (<jats:styled-content style="fixed-case">IPW</jats:styled-content>) with propensity score and multiple linear regression, estimating nonstandardized coefficients (β) and 95% confidence intervals (CIs), were used.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The baseline response rate was 65.2%, and the follow‐up rate was 70.1%. During the follow‐up period, participants’ <jats:styled-content style="fixed-case">TMIG</jats:styled-content>‐<jats:styled-content style="fixed-case">IC</jats:styled-content> score declined by an average of 0.247 points (standard deviation: 1.446). The results showed a significant dose‐response association between tooth loss and decline in higher‐level functional capacity in multiple linear regression models. <jats:styled-content style="fixed-case">IPW</jats:styled-content> models estimated the increment in <jats:styled-content style="fixed-case">TMIG</jats:styled-content>‐<jats:styled-content style="fixed-case">IC</jats:styled-content> score (β<jats:italic> </jats:italic>= 0.170, 95% <jats:styled-content style="fixed-case">CI</jats:styled-content> = 0.114 to 0.227) if edentulous participants gained 20 or more natural teeth.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Tooth loss is associated with future decline in higher‐level functional capacity. <jats:styled-content style="fixed-case">IPW</jats:styled-content> models suggest that treatment for tooth loss attenuates decline in higher‐level functional capacity.</jats:p></jats:sec>

DOI： 10.1111/jgs.14324

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:sec><jats:title>Objective</jats:title><jats:p>To date, no study has prospectively examined the association between social capital (SC) in the community and oral health. The aim of this longitudinal cohort study was to examine the association between both community-level and individual-level SC and tooth loss in older Japanese people.</jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p>Prospective cohort study</jats:p></jats:sec><jats:sec><jats:title>Setting</jats:title><jats:p>We utilised data from the Japan Gerontological Evaluation Study (JAGES) performed in 2010 and 2013 and conducted in 525 districts.</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>The target population was restricted to non-institutionalised people aged 65 years or older. Participants included 51 280 people who responded to two surveys and who had teeth at baseline.</jats:p></jats:sec><jats:sec><jats:title>Primary outcome measure</jats:title><jats:p>The primary outcome measure was loss of remaining teeth, measured by the downward change of any category of remaining teeth, between baseline and follow-up.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The mean age of the participants was 72.5 years (SD=5.4). During the study period, 8.2% (n=4180) lost one or more of their remaining teeth. Among three community-level SC variables obtained from factor analysis, an indicator of civic participation significantly reduced the risk of tooth loss (OR 0.93; 95% CI 0.88 to 0.99). The individual-level SC variables ‘hobby activity participation’ and ‘sports group participation’ were also associated with a reduced risk of tooth loss (OR 0.88; 95% CI 0.81 to 0.95 and OR 0.90; 95% CI 0.82 to 0.99, respectively).</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Living in a community with rich SC and individuals with good SC is associated with lower incidence of tooth loss among older Japanese people.</jats:p></jats:sec>

DOI： 10.1136/bmjopen-2015-010768

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.socscimed.2016.01.008

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

<jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>The Great East Japan Earthquake in March 2011 destroyed many communities, and as a result many older victims lost their removable dentures. No previous studies have documented the prevalence of denture loss after a natural disaster or examined its negative impact. Therefore, investigation of the consequences of such a disaster on oral health is of major importance from a public health viewpoint.</jats:p></jats:sec><jats:sec><jats:title>Materials and Methods</jats:title><jats:p>Three to five months after the disaster, questionnaire surveys were conducted in two coastal towns, Ogatu and Oshika, located in the area of Ishinomaki city, Miyagi prefecture. Among the survey participants, 715 individuals had used one or more removable dentures before the disaster, and these comprised the population analyzed. The effect of denture loss on oral health‐related quality life (OHRQoL) was examined by a modified Poisson regression approach with adjustment for sex, age, subjective household economic status, dental caries, tooth mobility, psychological distress (K6), access to a dental clinic, physical activity, and town of residence.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>There were 123 (17.2%) participants who had lost their dentures. In comparison with participants who had not lost their dentures, those lacking dentures showed a significantly higher relative risk for eating difficulties (RR = 2.65, 95%CI = 1.90–3.69), speech problems (RR = 4.37, 95%CI = 2.46–7.76), embarrassment upon smiling, laughing, or showing their teeth (RR = 5.32, 95%CI = 2.34–12.1), emotional distress (RR = 2.38, 95%CI = 1.41–4.03), and problems related to social interaction (RR = 6.97, 95%CI = 1.75–27.7).</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Denture loss appeared to impair eating and speaking ability, thus discouraging communication with others. Public health intervention after major natural disasters should include dental care.</jats:p></jats:sec>

DOI： 10.1111/jopr.12210

researchmap

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.5834/jdh.65.5_417

researchmap

記述言語：日本語   会議種別：口頭発表（一般）  

researchmap

記述言語：英語   会議種別：口頭発表（一般）  

researchmap

記述言語：日本語   会議種別：ポスター発表  

researchmap

記述言語：日本語   会議種別：ポスター発表  

researchmap

記述言語：英語   会議種別：口頭発表（一般）  

researchmap

記述言語：英語   会議種別：ポスター発表  

researchmap

記述言語：日本語   会議種別：ポスター発表  

researchmap

記述言語：日本語   会議種別：ポスター発表  

researchmap