Updated on 2025/03/06

写真a

 
HIROFUJI Aina
 
Organization
School of Medicine Medical Course Clinical Medicine Surgery [Division of Cardiovascular Surgery]
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Education

  • Kurume University   Faculty of Medicine

    - 2017.3

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    Country: Japan

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Papers

  • A case of non-bacterial thrombotic endocarditis on the aortic valve following coronary angiography. International journal

    Nobuhiro Motiduki, Ryohei Ushioda, Sayaka Yuzawa, Kazuki Miyatani, Hideki Isa, Yuki Setogawa, Kohei Ishidou, Masahiko Narita, Fumitaka Suzuki, Aina Hirofuji, Ryo Okubo, Shingo Kunioka, Masahiro Tsutsui, Natsuya Ishikawa, Kamiya Hiroyuki

    Journal of surgical case reports   2024 ( 4 )   rjae212   2024.4

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    Nonbacterial thrombotic endocarditis (NBTE) on the aortic valve involves fibrin and platelet aggregate formation, potentially leading to embolic events. We present a case of NBTE on the aortic valve following coronary angiography (CAG) in a 54-year-old man with multiple comorbidities. Surgical thrombectomy was performed owing to acute cerebral infarcts. This case highlights the significance of considering that mechanical trauma from catheterization during CAG can trigger thrombus formation.

    DOI: 10.1093/jscr/rjae212

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  • [Early Outcomes and Indications for Surgical Intervention of Preoperative Atrial Fibrillation].

    Hideki Isa, Kazuki Miyatani, Nobuhiro Mochizuki, Fumitaka Suzuki, Yuki Setogawa, Aina Hirofuji, Shingo Kunioka, Masahiro Tsutsui, Natsuya Ishikawa, Hiroyuki Kamiya

    Kyobu geka. The Japanese journal of thoracic surgery   77 ( 1 )   4 - 8   2024.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    BACKGROUND: This study investigates short-term outcomes following surgical interventions for atrial fibrillation (Af), including the Cox-maze Ⅳ procedure (maze procedure) and pulmonary vein isolation (PVI), performed concurrently with other cardiac surgeries. Additionally, we aim to determine the indications for surgical intervention for Af. METHOD: We retrospectively studied a total of 1,580 patients, out of which 274 had preoperative Af, that underwent cardiac surgery between January 2015 and April 2023. Patients who underwent emergency surgery, died in the hospital postoperatively, or received pacemaker implantation were excluded. Patients were first divided into two groups:the intervention group (n=135, 53.6%) and the non-intervention group( n=117, 46.4%), further categorized by whether they were in sinus rhythm at discharge. The intervention group was then subdivided into the maze procedure group( n=54), and the PVI group (n=76). RESULTS: Within the maze procedure group, significant differences were observed between the sinus rhythm and non-sinus rhythm groups in terms of age, preoperative Af duration, and aortic valve intervention status. In the PVI group, patients with persistent Af, longer preoperative Af duration, and larger left atrium diameter( LAD) were less likely to return to sinus rhythm. Smaller LAD was also a significant factor for returning to sinus rhythm in the non-intervention group. Multivariate analysis for all patients revealed that an LAD smaller than 50 mm was the strongest predictor for returning to sinus rhythm post operation( p<0.01). CONCLUSION: For patients with persistent Af, the maze procedure is favored over PVI as a surgical intervention. When LAD exceeds 50 mm, the likelihood of returning to sinus rhythm is diminished.

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  • Off-pump minimally invasive coronary artery bypass grafting in patients with left ventricular dysfunction: the lampang experience. International journal

    Ryohei Ushioda, Aina Hirofuji, Dit Yoongtong, Boonsap Sakboon, Jaroen Cheewinmethasiri, Hiroyuki Kamiya, Nuttapon Arayawudhikul

    Frontiers in surgery   11   1324343 - 1324343   2024

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    INTRODUCTION: The minimally invasive cardiac surgery off-pump coronary artery bypass (MICSOPCAB) is technically difficult; therefore, previous studies have indicated that MICSOPCAB should be contraindicated in patients with impaired left ventricular (LV) function. In this study, we investigated the feasibility of MICSOPCAB in patients with impaired LV function. METHODS: The 226 patients underwent MICSOPCAB between August 2017 and September 2022. Our study defined impaired LV function as ejection fraction (EF) in echocardiography 40% or less. The patients were divided into Low EF group (n = 39) and Normal EF group (n = 187). RESULTS: The Low EF group was in a more critical preoperative condition than Normal EF group (41.0% in the Low EF group vs. 14.4% in the Normal EF group; p < 0.001). For preoperative transthoracic echocardiography, LV end-diastolic diameter (5.5 ± 0.9 cm in the Low EF group vs. 5.0 ± 0.8 cm in the Normal EF group; p < 0.001) and LV end-systolic diameter (4.4 ± 1.0 cm in the Low EF group vs. 3.4 ± 1.0 cm in the Normal EF group; p < 0.001) were significantly larger in the Low EF group. No differences were found in the operative time (180 [160-240] min in the Low EF group vs. 205 [165-253] min in the Normal EF group; p = 0.231) and the median number of distal anastomoses (2 [1-2] in the Low EF group vs. 2 [1-3] in the Normal EF group; p = 0.073). Intensive care unit stay was longer in the Low EF group than in the Normal EF group (2 [1-2] in the Low EF group vs. 1 [1-2] in the Normal EF group; p = 0.010). Perioperative transfusion was more common in the Low EF group than in the Normal EF group (69.7% vs. 49.2%; p = 0.023). There were no differences in major complications, hospital stay, and 30-day mortality. The Kaplan-Meier curve showed no significant difference in postoperative major adverse cardiac or cerebrovascular events rates between the two groups (p = 0.185). CONCLUSION: In this study, MICSOPCAB can be performed in patients with low EF having short- and mid-term outcomes similar to patients with normal EF. Therefore, low EF should not be contraindicated in MICSOPCAB.

    DOI: 10.3389/fsurg.2024.1324343

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  • Two-stage repair for DeBakey type II acute aortic dissection and distal aortic arch aneurysm in a nonagenarian patient. International journal

    Kentaro Shirakura, Shingo Kunioka, Kazuki Miyatani, Nobuhiro Mochizuki, Hideki Isa, Yuki Setogawa, Fumitaka Suzuki, Ryo Okubo, Ryohei Ushioda, Aina Hirofuji, Masahiro Tsutsui, Natsuya Ishikawa, Hiroyuki Kamiya

    Journal of surgical case reports   2023 ( 12 )   rjad648   2023.12

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    Although total arch replacement would be performed in a patient with acute type A aortic dissection and concomitant aortic aneurysm in the distal aortic arch, total arch replacement may be too invasive in elderly patients with significant morbidities. A 92-year-old female with acute type II DeBakey aortic dissection and concomitant distal aortic arch aneurysm was successfully treated with hemi-arch replacement followed by thoracic endovascular aortic repair. Hybrid two-stage repair of DeBakey type II aortic dissection complicated by distal arch aneurysm using thoracic endovascular aortic repair after hemi-arch replacement may be effective.

    DOI: 10.1093/jscr/rjad648

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  • Interventional Bridging Therapy for Radical Cardiac Surgery in a Patient Seemed to be Inoperable Due to Very Poor Left Ventricular Function: A Case Report. International journal

    JeongA Lee, Masahiro Tsutsui, Nobuhiro Mochizuki, Yuki Setogawa, Fumitaka Suzuki, Masahiko Narita, Aina Hirofuji, Shingo Kunioka, Tomonori Shirasaka, Natsuya Ishikawa, Sayaka Yuzawa, Hiroyuki Kamiya

    The heart surgery forum   26 ( 6 )   E676-E679   2023.11

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    Cases that are inoperable owing to poor preoperative conditions are sometimes encountered. However, there are some cases that are led to radical treatment by performing bridge therapy. Here, we presented a case of a patient with complex cardiac disease in an inoperable state who underwent bridging therapy that led to successful surgical treatment. A 73-year-old male who received hemodialysis treatment and had severe aortic valve stenosis and coronary artery disease planned surgical treatment. However, he was deemed inoperable owing to his low cardiac function and hemodynamic instability. Therefore, to escape from a fatal condition, we first performed balloon aortic valvuloplasty and percutaneous coronary intervention as palliative procedures. Subsequently, his cardiac function and hemodynamic stability remarkably improved; therefore, after 1 month, we performed a successful radical surgical treatment. Even in inoperable patients, bridging therapy leading to radical treatment is possible.

    DOI: 10.59958/hsf.5779

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  • Evaluating Short-Term Postoperative Outcomes in Minimally Invasive Mitral Valve Surgery for Patients with Rheumatic Disease. International journal

    Ryohei Ushioda, Tomonori Shirasaka, Boonsap Sakboon, Jaroen Cheewinmethasiri, Dit Yoongtong, Aina Hirofuji, Hiroyuki Kamiya, Nuttapon Arayawudhikul

    The heart surgery forum   26 ( 2 )   E178-E182   2023.4

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    Minimally invasive mitral valve surgery (MIMVS) is widespread and has become a standard procedure in cardiac surgery [Chitwood 1997; Carpentier 1996]. Therefore, MIMVS is a common procedure for patients with degenerative disease [Raanani 2010; Iribarne 2010] as well. However, the safety of MIMVS in patients with rheumatic heart disease (RHD) has not thoroughly been investigated, due to the low prevalence of RHD in developed countries, where MIMVS is standardized [Miceli 2015]. Here, we investigated the safety of MIMVS for patients with RHD at Lampang Hospital in Thailand.

    DOI: 10.1532/hsf.5391

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  • Giant Coronary Aneurysm with Coronary-Pulmonary Artery Fistula in a Jehovah's Witness. International journal

    Aina Hirofuji, Azusa Furugen, Takeshi Kamada, Kenji Yamazaki, Hiroyuki Kamiya, Hirosato Doi

    The Thoracic and cardiovascular surgeon reports   12 ( 1 )   e1-e3   2023.1

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    With an incidence of 3 in 100 million, giant coronary artery aneurysm (CAA) with coronary artery fistula (CAF) is a very rare condition. To prevent rupture, giant CAA with CAF should be swiftly treated. We present a Jehovah's Witness patient with giant CAA and coronary-pulmonary artery fistula. We resected the giant CAA in one piece, while ligating the CAF, without allogeneic blood transfusion. Due to rarity of these conditions, many thoracic surgeons lack direct experience in its surgical procedures. Herein, we share footage of this surgery as an example of how to safely resect CAA with minimal bleeding.

    DOI: 10.1055/s-0042-1757877

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  • 急性心筋梗塞後のoozing rupture,乳頭筋断裂による僧帽弁閉鎖不全症と左室瘤に対してstaged therapyを行った1例

    福田 はな, 広藤 愛菜, 望月 伸浩, 瀬戸川 友紀, 鈴木 文隆, 成田 昌彦, 國岡 信吾, 筒井 真博, 白坂 知識, 石川 成津矢, 紙谷 寛之

    北海道外科雑誌   67 ( 2 )   196 - 197   2022.12

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    Language:Japanese   Publisher:北海道外科学会  

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  • ECG-gated helical CTを用いた術前大動脈弁輪径測定により大動脈弁置換術はより安全により迅速化できる

    白坂 知識, 望月 伸治, 瀬戸川 有紀, 成田 昌彦, 鈴木 文隆, 広藤 愛菜, 國岡 信吾, 筒井 真博, 石川 成津矢, 紙谷 寛之

    日本胸部外科学会定期学術集会   75回   OP1 - 1   2022.10

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    Language:Japanese   Publisher:(一社)日本胸部外科学会  

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  • Mitral valve replacement with papillary muscle tugging approximation in a patient with severely impaired left ventricular function 14 years after initial mitral valve repair. International journal

    Tomoki Nakatsu, Tomonori Shirasaka, Aina Hirofuji, Hiroyuki Kamiya

    Journal of surgical case reports   2022 ( 8 )   rjac339   2022.8

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    The best treatment for ventricular functional mitral regurgitation still remains unclear. Papillary muscle tugging approximation (PMTA) is a technique known to preserve function of the sub-valvular apparatus, keeping it functionally in synch with the left ventricle systolic and diastolic dynamics. Herein, we present a case of mitral valve replacement with PMTA in a patient with severely impaired left ventricular function 14 years post initial mitral valve repair, which significantly improved during a course of 4 years after the reoperation without any complications.

    DOI: 10.1093/jscr/rjac339

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  • Microvascular thrombi in recurrent myocardial injury after coronavirus disease 2019 infection. International journal

    Tadao Aikawa, Jiro Ogino, Aina Hirofuji, Noriko Oyama-Manabe

    European heart journal   42 ( 36 )   3804 - 3804   2021.9

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    DOI: 10.1093/eurheartj/ehab539

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  • Proximalized Total Arch Replacement Can Be Safely Performed by Trainee. International journal

    Sentaro Nakanishi, Naohiro Wakabayashi, Hayato Ise, Hiroto Kitahara, Aina Hirofuji, Natsuya Ishikawa, Hiroyuki Kamiya

    The Thoracic and cardiovascular surgeon   69 ( 4 )   336 - 344   2021.6

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    BACKGROUND: The aim of the present study was to validate safety of total arch replacement (TAR) using a novel frozen elephant trunk device, operated by trainees as surgical education. METHODS: Sixty-four patients including 19 patients (29.6%) with acute aortic dissection type A (AADA) underwent TAR in our institute between April 2014 and March 2019 were retrospectively analyzed. Twenty-nine patients were operated by trainees (group T) and 35 patients were operated by attending surgeons (group A). RESULTS: Patient characteristics did not differ between groups. Operative time (409.4 ± 87.8 vs. 468.6 ± 129.6 minutes, p = 0.034), cardiopulmonary bypass time (177.7 ± 50.4 vs. 222.9 ± 596.7 minutes, p = 0.019), and hypothermic circulatory arrest time (39.5 ± 13.4 vs. 54.5 ± 18.5 minutes, p = 0.001) were significantly shorter in group A than in group T, but aortic clamping time did not differ between groups (115.3 ± 55.7 vs. 114.2 ± 35.0 minutes, p = 0.924) because the rate of concomitant surgery was higher in group A (37.1 vs. 10.3%, p = 0.014). Thirty-day mortality was 3.1% in the entire cohort. Although operation time was longer in group T, there were no significant difference in postoperative results between the groups, and the experience levels of the main operator were not independent predictors for in-hospital mortality + major postoperative complications. There was no difference in late death and aortic events between groups. CONCLUSIONS: The present study demonstrated that TAR can be safely performed by trainees, and suggests TAR as a possible and safe educational operation.

    DOI: 10.1055/s-0040-1713354

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  • Rupture of aneurysmal coronary-to-pulmonary artery fistula in a 96-year-old female; report of a case.

    Haruka Murakami, Sentaro Nakanishi, Aina Hirofuji, Hiroyuki Kamiya

    General thoracic and cardiovascular surgery   69 ( 3 )   601 - 604   2021.3

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    Coronary artery fistula (CAF) is a relatively rare congenital abnormality of the coronary arteries; typically, patients who undergo surgery for CAFs are relatively young because it is a congenital disease. Here we present a case of an aneurysmal coronary-to-pulmonary artery fistula rupture in a 96-year-old female. Considering her extreme high age and missing preoperative diagnostics, only local hemostasis without anatomical repair was performed but the patient is still doing well 1 year after the operation.

    DOI: 10.1007/s11748-020-01488-y

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  • Awake Surgical Mitral Valve Repair after Transcatheter Aortic Valve Replacement. International journal

    Aina Hirofuji, Hirotsugu Kanda, Yuya Kitani, Hiroyuki Kamiya

    The Thoracic and cardiovascular surgeon reports   10 ( 1 )   e15-e17   2021.1

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    Transcatheter aortic valve replacement has become a popular choice for cases with severe aortic stenosis. However, when severe mitral regurgitation is comorbid in high-risk patients with severe aortic stenosis, therapeutic options must be weighed for each case. Here we present a very frail 88-year-old patient with severe aortic stenosis and severe mitral valve regurgitation who underwent a successful awake minimally invasive mitral valve repair after transcatheter aortic valve replacement.

    DOI: 10.1055/s-0040-1718774

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  • クラウド型遠隔医療システムにより速やかな診断が行われ、ステントグラフトを瘤内に留置することで治療できた胸腹部大動脈瘤破裂の1例

    高橋 一輝, 若林 尚宏, 石堂 耕平, 広藤 愛菜, 中西 仙太郎, 石川 成津矢, 古屋 敦宏, 東 信良, 紙谷 寛之

    北海道外科雑誌   65 ( 2 )   164 - 168   2020.12

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    症例は70歳代女性、胸腹部大動脈瘤破裂で前医より緊急搬送された。クラウド型遠隔医療システムを用いて、前医にて撮像されたCTを転送し、患者到着前から治療戦略を決定することで迅速に手術を行うことができた。CTでは並列に起始する腹腔動脈(CA)、上腸間膜動脈(SMA)を巻き込み、腎動脈直上に及ぶ最大径78mmの大動脈瘤とその周囲への造影剤の漏出を認めた。大動脈造影にてCAより中枢側に破裂孔を認め、ステントグラフト(SG)をCA・SMA直上の瘤内に留置した。退院直前のCTにて瘤径の拡大を認めたため術後67日に胸腹部人工血管置換術を行った。術後肺炎を契機に敗血症を発症しSG挿入術から265日後に死亡した。手術前・周術期死亡率の高い本疾患において、クラウド型遠隔医療システムを用いることで迅速にSG挿入術を行い、破裂孔閉鎖を行うことができた。次の治療につなぐことが出来た点において胸腹部大動脈瘤破裂治療の選択肢になりうると考えられる。(著者抄録)

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    Other Link: https://search.jamas.or.jp/default/link?pub_year=2020&ichushi_jid=J01375&link_issn=&doc_id=20210115020012&doc_link_id=%2Fdc7hksrg%2F2020%2F006502%2F013%2F0164-0168%26dl%3D0&url=https%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fdc7hksrg%2F2020%2F006502%2F013%2F0164-0168%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

  • Impella CP for treatment of left ventricular free-wall rupture after myocardial infarction: Report of a case. International journal

    Natsuya Ishikawa, Aina Hirofuji, Shingo Kunioka, Tomonori Shirasaka, Naohiro Wakabayashi, Yuya Kitani, Hiroyuki Kamiya

    Journal of surgical case reports   2020 ( 8 )   rjaa263   2020.8

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    Unloading of the left ventricle (LV) is essential for the treatment of LV free-wall rupture (LVFWR), and it is well-known that the LV can be optimally unloaded with the Impella system. However, there has been no report on applying the Impella system for the treatment of LVFWR. Here, we report a patient with FWR after massive myocardial infarction who was successfully treated with non-suture repair via median sternotomy and implantation of Impella CP (Abiomed, Danvers, MA).

    DOI: 10.1093/jscr/rjaa263

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  • Sutureless technique using the left atrial appendage for left pulmonary vein occlusion after catheter ablation. International journal

    Naohiro Wakabayashi, Aina Hirofuji, Natsuya Ishikawa, Hiroyuki Kamiya

    Surgical case reports   6 ( 1 )   179 - 179   2020.7

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    BACKGROUND: Pulmonary vein stenosis or occlusion is a rare but one of the most devastating complications after catheter ablation for cardiac arrhythmias, and surgical repair is an option in severe cases. The sutureless technique, which avoids direct suture of vessel walls, was initially described for congenital pulmonary vein stenosis and has been widely performed due to its good restenosis-free rate. CASE PRESENTATION: A 52-year-old male developed left pulmonary vein occlusion after catheter ablation for atrial fibrillation. The surgical repair with sutureless technique using the left atrial appendage was performed without any complications. Postoperative computed tomography demonstrated the revascularization of the pulmonary vein. CONCLUSIONS: The sutureless technique using the left atrial appendage is significantly reasonable particularly in case of left pulmonary vein stenosis or occlusion after catheter ablation for atrial fibrillation since it reduces the risks of restenosis and thromboembolism.

    DOI: 10.1186/s40792-020-00930-w

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  • Aorto-Right Atrial Fistula after Minimally Invasive Tricuspid Valve Repair: A Report of Two Cases. International journal

    Kouhei Ishidou, Aina Hirofuji, Naohiro Wakabayashi, Hiroyuki Kamiya

    The Thoracic and cardiovascular surgeon reports   9 ( 1 )   e55-e57   2020.1

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    We experienced two cases of postoperative iatrogenic aorto-right atrial fistula (ARAF) after tricuspid valve repair (TVR) using minimally invasive cardiac surgery (MICS) technique. In both the cases, the flow of ARAF passed through the sinus of Valsalva near the noncoronary cusp (NCC)/right coronary cusp (RCC) commissure or NCC to right atrium. The quality of the fine needle used in the MICS technique may be inferior to that used in conventional surgery; ARAF after TVR could be a unique pitfall with the MICS technique.

    DOI: 10.1055/s-0040-1718552

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  • The Cause of Massive Hemoptysis After Thoracic Endovascular Aortic Repair May Not Always Be an Aortobronchial Fistula: Report of a Case. International journal

    Natsuya Ishikawa, Aina Hirofuji, Naohiro Wakabayashi, Sentaro Nakanishi, Hiroyuki Kamiya

    Clinical medicine insights. Case reports   13   1179547620939078 - 1179547620939078   2020

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    Hemoptysis after thoracic endovascular/open aortic repair is relatively rare but a well-known complication, and normally diagnosed with aortobronchial fistula (ABF). Here, we present a patient who suffered from recurrent massive hemoptyses even after multiple thoracic endovascular aortic repairs (TEVARs), where hemoptysis was ultimately controlled by pneumonectomy. In this case, the bleeding source was not the aorta but the lung parenchyma itself, indicating the importance of raising awareness that the cause of massive hemoptysis after TEVAR may not always be an ABF.

    DOI: 10.1177/1179547620939078

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  • Debranching TEVARにおける周術期脳梗塞予防のためのECMOサポート付き脳分離術(ECMO supprted brain isolation to prevent perioperative stroke during debranching TEVAR)

    若林 尚宏, 石堂 耕平, 広藤 愛菜, 高橋 一輝, 中西 仙太郎, 石川 成津矢, 紙谷 寛之

    日本血管外科学会雑誌   29 ( Suppl. )   SF9 - 6   2020

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  • Failed transcatheter pulmonary artery embolization in a patient suffering from massive hemoptysis after thoracic endovascular aortic repair. International journal

    Natsuya Ishikawa, Shinsuke Kikuchi, Kouhei Ishidou, Aina Hirofuji, Sentaro Nakanishi, Hayato Ise, Naohiro Wakabayashi, Hiroyuki Kamiya

    Clinical medicine insights. Case reports   12   1179547619896577 - 1179547619896577   2019

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    An emergency thoracic endovascular aortic repair (TEVAR) with zone 2 landing without revascularization of the left subclavian artery was performed due to the impending rupture of a distal arch aneurysm in an old patient presenting hemoptysis. Two months later, the patient had recurrent massive hemoptyses and continued after additional zone 0 TEVAR. The lung parenchyma was considered to be the bleeding source and transcatheter pulmonary artery embolization was performed, and the episodes of massive hemoptysis appeared to have ceased. However, the patient died of sudden recurrent massive hemoptysis 40 days later. Inflammation and/or infection of the lung parenchyma adjunct to the aortic aneurysm could be cause of fatal hemoptysis, and aggressive therapy such as lung resection should be considered in such patients.

    DOI: 10.1177/1179547619896577

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MISC

Presentations

  • 心筋再生治療を目指して:Mycによる心筋細胞分裂誘導と心筋梗塞後の心機能保護

    広藤愛菜, 小山恭平, 田中宏樹, 宮谷和樹, 伊佐秀貴, 瀬戸川友紀, 鈴木文隆, 大久保諒, 潮田亮平, 國岡信吾, 筒井真博, 石川成津矢, 紙谷寛之

    第54回日本心臓血管外科学会学術 

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    Event date: 2024.2

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • Myc Induces Cardiomyocyte Mitosis in Adult Mice International conference

    Keystone Symposia, Heart Failure: All Cells Considered 

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    Event date: 2023.6

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  • Trim28 knockout accelerates isoproterenol-induced heart mass increase International conference

    Keystone Symposia, Heart Failure: All Cells Considered 

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    Event date: 2023.6

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  • H3K9me3の脱メチル化によるトランスポゾンの活性化は心筋細胞の遺伝子発現に影響を与える

    辻田 悠希, 小山 恭平, 広藤 愛菜, 潮田 亮平, 紙谷 寛之

    第45回日本分子生物学会年会 

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    Event date: 2022.11 - 2022.12

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  • 心筋細胞の細胞周期に対するMycの特性評価

    広藤 愛菜, 小山 恭平, 河村 あさみ, 田中 彩乃, 辻田 悠希, 潮田 亮平, 神田 恵, 紙谷 寛之

    第45回日本分子生物学会年会 

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    Event date: 2022.11 - 2022.12

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  • 急性心筋梗塞後のoozing rupture,乳頭筋断裂による僧帽弁閉鎖不全症および左室瘤に対してstaged therapyを行った1例

    福田 はな, 広藤 愛菜, 望月 伸浩, 瀬戸川友紀, 鈴木 文隆, 成田 昌彦, 國岡 信吾, 筒井 真博, 白坂 知識, 石川成津矢, 紙谷 寛之

    第111回北海道外科学会 

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    Event date: 2022.9

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 心室細動を契機に診断された右冠動脈起始異常症に対して冠動脈バイパス術を施行した1例

    清水 要, 広藤 愛菜, 望月 伸浩, 瀬戸川友紀, 鈴木 文隆, 成田 昌彦, 國岡 信吾, 筒井 真博, 白坂 知識, 石川成津矢, 紙谷 寛之

    第122回日本臨床外科学会北海道支部例会 

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    Event date: 2022.9

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 重複大動脈弓と心室中隔欠損症に対して二期的に手術治療を行った1例

    橋本 侑樹, 広藤 愛菜, 望月 伸浩, 鈴木 文隆, 瀬戸川友紀, 成田 昌彦, 國岡 信吾, 筒井 真博, 白坂 知識, 石川成津矢, 紙谷 寛之

    第111回北海道外科学会 

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    Event date: 2022.9

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  • 狭心症発症を契機に診断された冠動脈肺動脈瘻より発生する3cm大の冠動脈瘤に対する1手術例

    丸岡 純, 広藤 愛菜, 望月 伸浩, 瀬戸川友紀, 鈴木 文隆, 成田 昌彦, 國岡 信吾, 筒井 真博, 白坂 知識, 紙谷 寛之

    第122回日本臨床外科学会北海道支部例会 

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    Event date: 2022.9

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  • 巨大冠動脈瘤と冠動脈肺動脈瘻を合併した1手術例

    広藤愛菜, 古堅あずさ, 鎌田武, 山崎健二, 道井洋吏

    第4回北海道外科関連学会機構合同学術集会 

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    Event date: 2021.9

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 生体弁による僧帽弁置換術後1年以内に人工弁機能不全を来し,僧帽弁再置換術を要した1例

    広藤愛菜, 古堅あずさ, 鎌田武, 山崎健二, 道井洋吏

    第125回日本循環器学会北海道地方会 

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    Event date: 2021.6

    Language:Japanese   Presentation type:Oral presentation (general)  

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Awards

  • 第54回日本心臓血管外科学会学術総会 優秀賞(基礎研究領域)

    2024.2   特定非営利活動法人日本心臓血管外科学会  

    広藤愛菜, 小山恭平, 田中宏樹, 宮谷和樹, 伊佐秀貴, 瀬戸川友紀, 鈴木文隆, 大久保諒, 潮田亮平, 國岡信吾, 筒井真博, 石川成津矢, 紙谷寛之

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    Award type:International academic award (Japan or overseas)  Country:Japan

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  • 第54回日本心臓血管外科学会学術総会 最優秀賞

    2024.2   特定非営利活動法人日本心臓血管外科学会  

    広藤愛菜, 小山恭平, 田中宏樹, 宮谷和樹, 伊佐秀貴, 瀬戸川友紀, 鈴木文隆, 大久保諒, 潮田亮平, 國岡信吾, 筒井真博, 石川成津矢, 紙谷寛之

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    Award type:International academic award (Japan or overseas)  Country:Japan

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Research Projects

  • Mycを用いた心筋細胞分裂誘導メカニズムの解明と心筋再生治療の基盤構築

    Grant number:23K08225  2023.4 - 2026.3

    日本学術振興会  (選択しない)  基盤研究(C)

    広藤 愛菜, 小山 恭平

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    Grant amount:\4,680,000 ( Direct Cost: \3,600,000 、 Indirect Cost:\1,080,000 )

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  • Fabrication of biodegradable nanofiber grafts for the coronary-bypass surgery

    Grant number:22H03154  2022.4 - 2026.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

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    Grant amount:\17,290,000 ( Direct Cost: \13,300,000 、 Indirect Cost:\3,990,000 )

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  • Manipulating histone modification to induce cardiac proliferation and heart regeneration

    Grant number:20K17070  2020.4 - 2023.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Early-Career Scientists

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    Grant amount:\4,160,000 ( Direct Cost: \3,200,000 、 Indirect Cost:\960,000 )

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  • ヒストン修飾H3K9me3が制御する心臓再生メカニズムの解明 International coauthorship

    (選択しない) 

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