1 - 40 of about 40
English: Kono M, Wakisaka R, Komatsuda H, Hayashi R, Kumai T, Yamaki H, Sato R, Nagato T, Ohkuri T, Kosaka A, Ohara K, Kishibe K, Kobayashi H, Hayashi T, Takahara M., Immunotherapy targeting tumor-associated antigen in a mouse model of head and neck cancer , Head Neck , 2024
English: Nagato T, Komatsuda H, Hayashi R, Takahara M, Ujiie N, Kosaka A, Ohkuri T, Oikawa K, Sato R, Wakisaka R, Kono M, Yamaki H, Ohara K, Kumai T, Kishibe K, Katada A, Hayashi T, Kobayashi H., Soluble CD27 as a predictive biomarker for intra-tumoral CD70/CD27 interaction in nasopharyngeal carcinoma , Cancer Science , 2024
English: Murai A, Kubo T, Ohkuri T, Yanagawa J, Yajima Y, Kosaka A, Li D, Nagato T, Murata K, Kanaseki T, Tsukahara T, Nagasaki T, Hirohashi Y, Kobayashi H, Torigoe T., NF9 peptide specific cytotoxic T lymphocyte clone cross react to Y453F mutation of SARS-CoV-2 virus spike protein , Immunological Medicine , 2024
English: Yajima Y, Kosaka A, Ohkuri T, Hirohashi Y, Li D, Nagasaki T, Nagato T, Torigoe T, Kobayashi H., SARS-CoV-2 spike protein-derived immunogenic peptides that are promiscuously presented by several HLA-class II molecules and their potential for inducing acquired immunity , Heliyon , vol.9 (9) (p.e20192 - ) , 2023
English: Yamaki H, Kono M, Wakisaka R, Komatsuda H, Kumai T, Hayashi R, Sato R, Nagato T, Ohkuri T, Kosaka A, Ohara K, Kishibe K, Takahara M, Hayashi T, Kobayashi H, Katada A., Brachyury-targeted immunotherapy combined with gemcitabine against head and neck cancer , Cancer Immunology, Immunotherapy , 2023
English: Nagato T, Komatsuda H, Hayashi R, Takahara M, Kishibe K, Yasuda S, Yajima Y, Kosaka A, Ohkuri T, Oikawa K, Harabuchi S, Kono M, Yamaki H, Wakisaka R, Hirata-Nozaki Y, Ohara K, Kumai T, Katada A, Hayashi T, Harabuchi Y, Kobayashi H., Expression of soluble CD27 in extranodal natural killer/T-cell lymphoma, nasal type: potential as a biomarker for diagnosis and CD27/CD70-targeted therapy , Cancer Immunology, Immunotherapy , 2023
English: Kosaka A, Yajima Y, Yasuda S, Komatsuda H, Nagato T, Oikawa K, Kobayashi H, Ohkuri T., Celecoxib promotes the efficacy of STING-targeted therapy by increasing antitumor CD8+ T-cell functions via modulating glucose metabolism of CD11b+Ly6G+ cells , International Journal of Cancer , 2022 , (IF:6.4)
English: Komatsuda H, Wakisaka R, Kono M, Kumai T, Hayashi R, Yamaki H, Sato R, Nagato T, Ohkuri T, Kosaka A, Ohara K, Takahara M, Katada A, Kobayashi H., Mitogen-activated protein kinase inhibition augments the T cell response against HOXB7-expressing tumor through human leukocyte antigen upregulation , Cancer Science , 2022 , (IF:5.7)
English: Yajima Y, Kosaka A, Ishibashi K, Yasuda S, Komatsuda H, Nagato T, Oikawa K, Kitada M, Takekawa M, Kumai T, Ohara K, Ohkuri T, Kobayashi H., A tumor metastasis-associated molecule TWIST1 is a favorable target for cancer immunotherapy due to its immunogenicity , Cancer Science , vol.113 (8) (p.2526 - 2535) , 2022 , (IF:5.7)
English: Kono M, Komatsuda H, Yamaki H, Kumai T, Hayashi R, Wakisaka R, Nagato T, Ohkuri T, Kosaka A, Ohara K, Kishibe K, Takahara M, Katada A, Hayashi T, Kobayashi H, Harabuchi Y., Immunomodulation via FGFR inhibition augments FGFR1 targeting T-cell based antitumor immunotherapy for head and neck squamous cell carcinoma , Oncoimmunology , 2022
English: Kosaka A, Ishibashi K, Nagato T, Kitamura H, Fujiwara Y, Yasuda S, Nagata M, Harabuchi S, Hayashi R, Yajima Y, Ohara K, Kumai T, Aoki N, Komohara Y, Oikawa K, Harabuchi Y, Kitada M, Kobayashi H, Ohkuri T., CD47 blockade enhances the efficacy of intratumoral STING-targeting therapy by activating phagocytes. , Journal of Experimental Medicine , vol.218 (11) (p.e20200792 - ) , 2021 , (IF:17.579)
English: Ohkuri T, Kosaka A, Ikeura M, Salazar AM, Okada H., IFN-γ- and IL-17-producing CD8+ T (Tc17-1) cells in combination with poly-ICLC and peptide vaccine exhibit antiglioma activity. , Journal for ImmunoTherapy of Cancer , vol.9 (6) (p.e002426 - ) , 2021 , (IF:12.485)
English: Kosaka A, Yajima Y, Hatayama M, Ikuta K, Sasaki T, Hirai N, Yasuda S, Nagata M, Hayashi R, Harabuchi S, Ohara K, Ohara M, Kumai T, Ishibashi K, Hirata-Nozaki Y, Nagato T, Oikawa K, Harabuchi Y, Celis E, Okumura T, Ohsaki Y, Kobayashi H, Ohkuri T., A stealth antigen SPESP1, which is epigenetically silenced in tumors, is a suitable target for cancer immunotherapy. , Cancer Science , vol.112 (7) (p.2705 - 2713) , 2021 , (IF:6.518)
English: Kono M, Kumai T, Hayashi R, Yamaki H, Komatsuda H, Wakisaka R, Nagato T, Ohkuri T, Kosaka A, Ohara K, Kishibe K, Takahara M, Katada A, Hayashi T, Celis E, Kobayashi H, Harabuchi Y., Interruption of MDM2 signaling augments MDM2-targeted T cell-based antitumor immunotherapy through antigen-presenting machinery. , Cancer Immunology, Immunotherapy , 2021 , (IF:6.630)
English: Nagata M, Kosaka A, Yajima Y, Yasuda S, Ohara M, Ohara K, Harabuchi S, Hayashi R, Funakoshi H, Ueda J, Kumai T, Nagato T, Oikawa K, Harabuchi Y, Esteban C, Ohkuri T, Kobayashi H., A critical role of STING-triggered tumor-migrating neutrophils for anti-tumor effect of intratumoral cGAMP treatment. , Cancer Immunology, Immunotherapy , vol.70 (8) (p.2301 - 2312) , 2021 , (IF:6.630)
English: Hayashi R, Nagato T, Kumai T, Ohara K, Ohara M, Ohkuri T, Hirata-Nozaki Y, Harabuchi S, Kosaka A, Nagata M, Yajima Y, Yasuda S, Oikawa K, Kono M, Kishibe K, Takahara M, Katada A, Hayashi T, Celis E, Harabuchi Y, Kobayashi H., Expression of placenta-specific 1 and its potential for eliciting anti-tumor helper T-cell responses in head and neck squamous cell carcinoma , Oncoimmunology , vol.10 (1) (p.1856545 - ) , 2020 , (IF:8.110)
English: Ohara M, Ohara K, Kumai T, Ohkuri T, Nagato T, Hirata-Nozaki Y, Kosaka A, Nagata M, Hayashi R, Harabuchi S, Yajima Y, Oikawa K, Harabuchi Y, Sumi Y, Furukawa H, Kobayashi H, Phosphorylated vimentin as an immunotherapeutic target against metastatic colorectal cancer. , Cancer Immunology, Immunotherapy , 2020 , (IF:6.968)
English: Shohei Harabuchi; Akemi Kosaka; Yuki Yajima; Marino Nagata; Ryusuke Hayashi; Takumi Kumai; Kenzo Ohara; Toshihiro Nagato; Kensuke Oikawa; Mizuho Ohara; Yasuaki Harabuchi; Takayuki Ohkuri; Hiroya Kobayashi, Intratumoral STING activations overcome negative impact of cisplatin on antitumor immunity by inflaming tumor microenvironment in squamous cell carcinoma , Biochemical and Biophysical Research Communications , 2019 , (IF:2.985)
English: Yui Hirata‑Nozaki, Takayuki Ohkuri, Kenzo Ohara, Takumi Kumai, Marino Nagata, Shohei Harabuchi, Akemi Kosaka, Toshihiro Nagato, Kei Ishibashi, Kensuke Oikawa, Naoko Aoki, Mizuho Ohara, Yasuaki Harabuchi, Yuji Uno, Hidehiro Takei, Esteban Celis and Hiroya Kobayashi, PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma. , Journal of Translational Medicine , 2019 , (IF:4.124)
English: Kenzo Ohara, Takayuki Ohkuri, Takumi Kumai, Toshihiro Nagato, Yui Nozaki, Kei Ishibashi, Akemi Kosaka, Marino Nagata, Shohei Harabuchi, Mizuho Ohara, Kensuke Oikawa, Naoko Aoki, Yasuaki Harabuchi, Esteban Celis, Hiroya Kobayashi, Targeting phosphorylated p53 to elicit tumor-reactive T helper responses against head and neck squamous cell carcinoma , OncoImmunology , 2018 , (IF:5.333)
English: Ohkuri T, Kosaka A, Nagato T, Kobayashi H, Effects of STING stimulation on macrophages: STING agonists polarize into "classically" or "alternatively" activated macrophages? , Human Vaccines & Immunotherapeutics , vol.14 (2) (p.285 - 287) , 2018 , (IF:2.592)
English: Uehara J, Ohkuri T, Kosaka A, Ishibashi K, Hirata Y, Ohara K, Nagato T, Oikawa K, Aoki N, Harabuchi Y, Ishida-Yamamoto A, Kobayashi H, Intratumoral injection of IFN-β induces chemokine production in melanoma and augments the therapeutic efficacy of anti-PD-L1 mAb. , Biochemical and Biophysical Research Communications , vol.490 (2) (p.521 - 527) , 2017 , (IF:2.559)
English: Nagato T, Ohkuri T, Ohara K, Hirata Y, Kishibe K, Komabayashi Y, Ueda S, Takahara M, Kumai T, Ishibashi K, Kosaka A, Aoki N, Oikawa K, Uno Y, Akiyama N, Sado M, Takei H, Celis E, Harabuchi Y, Kobayashi H., Programmed death-ligand 1 and its soluble form are highly expressed in nasal natural killer/T-cell lymphoma: a potential rationale for immunotherapy. , Cancer Immunology, Immunotherapy , vol.66 (7) (p.877 - 890) , 2017 , (IF:4.225)
English: Ohkuri T, Kosaka A, Ishibashi K, Kumai T, Hirata Y, Ohara K, Nagato T, Oikawa K, Aoki N, Harabuchi Y, Celis E, Kobayashi H., Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site. , Cancer Immunology, Immunotherapy , vol.66 (6) (p.705 - 716) , 2017 , (IF:4.225)
English: Ishibashi K, Ohkuri T, Kosaka A, Nagato T, Hirata Y, Ohara K, Oikawa K, Aoki N, Kobayashi H. , Epigenetic modification augments the immunogenicity of human leukocyte antigen G serving as a tumor antigen for T cell-based immunotherapy , OncoImmunology , vol.5 (6) (p.e1169356 - ) , 2016 , (IF:7.719)
English: Ahn B, Kohanbash G, Ohkuri T, Kosaka A, Chen X, Ikeura M, Wang TC, Okada H., Histamine deficiency promotes accumulation of immunosuppressive immature myeloid cells and growth of murine gliomas. , Oncoimmunology , vol.4 (11) (p.e1047581 - ) , 2015 , (IF:7.644)
English: Kosaka A, Ohkuri T, Ikeura M, Kohanbash G, Okada H., Transgene-derived overexpression of miR-17-92 in CD8(+) T-cells confers enhanced cytotoxic activity. , Biochemical and Biophysical Research Communications , 2015 , (IF:2.371)
English: 1. Johnson LA, Scholler J, Ohkuri T, Kosaka A, Patel PR, McGettigan SE, Nace AK, Dentchev T, Thekkat P, Loew A, Boesteanu AC, Cogdill AP, Chen T, Fraietta JA, Kloss CC, Posey AD Jr, Engels B, Singh R, Ezell T, Idamakanti N, Ramones MH, Li N, Zhou L, Plesa G, Seykora JT, Okada H, June CH, Brogdon JL, Maus MV. , Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma. , Science Translational Medicine , 2015 , (IF:16.264)
English: Ohkuri T, Ghosh A, Kosaka A, Sarkar SN, Okada H, Protective role of STING against gliomagenesis: Rational use of STING agonist in anti-glioma immunotherapy , Oncoimmunology , vol.4 (4) (p.e999523 - ) , 2015 , (IF:7.644)
English: Ohkuri T, Ghosh A, Kosaka A, Zhu J, Ikeura M, David M, Watkins SC, Sarkar SN, Okada H., STING Contributes to Antiglioma Immunity via Triggering Type I IFN Signals in the Tumor Microenvironment. , Cancer Immunology Research , 2014 , (IF:3.857)
English: Kosaka A, Ohkuri T, Okada H. , Combination of an agonistic anti-CD40 monoclonal antibody and the COX-2 inhibitor celecoxib induces anti-glioma effects by promotion of type-1 immunity in myeloid cells and T-cells. , Cancer Immunology, Immunotherapy , vol.63 (8) (p.847 - 857) , 2014 , (IF:3.941)
English: Birukawa NK, Murase K, Sato Y, Kosaka A, Yoneda A, Nishita H, Fujita R, Nishimura M, Ninomiya T, Kajiwara K, Miyazaki M, Nakashima Y, Ota S, Murakami Y, Tanaka Y, Minomi K, Tamura Y, Niitsu Y., Activated hepatic stellate cells are dependent on self-collagen, cleaved by membrane type 1 matrix metalloproteinase for their growth. , The Journal of Biological Chemistry , vol.289 (29) (p.20209 - 20221) , 2014 , (IF:4.573)
English: Ohno M, Ohkuri T, Kosaka A, Tanahashi K, June CH, Natsume A, Okada H., Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenografts. , Journal for ImmunoTherapy of Cancer , 2013
English: Liu Y, Kosaka A, Ikeura M, Kohanbash G, Fellows-Mayle W, Snyder LA, Okada H., Premetastatic soil and prevention of breast cancer brain metastasis. , Neuro-Oncology , vol.15 (7) (p.891 - 903) , 2013 , (IF:5.286)
English: Kawashima T, Kosaka A, Yan H, Guo Z, Uchiyama R, Fukui R, Kaneko D, Kumagai Y, You DJ, Carreras J, Uematsu S, Jang MH, Takeuchi O, Kaisho T, Akira S, Miyake K, Tsutsui H, Saito T, Nishimura I, Tsuji NM., Double-stranded RNA of intestinal commensal but not pathogenic bacteria triggers production of protective interferon-β. , Immunity , vol.38 (6) (p.1187 - 1197) , 2013 , (IF:19.748)
English: Kosaka A, Yan H, Ohashi S, Gotoh Y, Sato A, Tsutsui H, Kaisho T, Toda T, Tsuji NM, Lactococcus lactis subsp. cremoris FC triggers IFN-γ production from NK and T cells via IL-12 and IL-18. , International Immunopharmacology , vol.14 (4) (p.729 - 733) , 2012 , (IF:2.417)
English: Kawashima T, Hayashi K, Kosaka A, Kawashima M, Igarashi T, Tsutsui H, Tsuji NM, Nishimura I, Hayashi T, Obata A., Lactobacillus plantarum strain YU from fermented foods activates Th1 and protective immune responses. , International Immunopharmacology , 2011 , (IF:2.376)
English: Fujiwara Y, Aiki Y, Yang L, Takaiwa F, Kosaka A, Tsuji NM, Shiraki K, Sekikawa K., Extraction and purification of human interleukin-10 from transgenic rice seeds. , Protein Expression and Purification , 2010 , (IF:1.644)
English: Kosaka A, Wakita D, Matsubara N, Togashi Y, Nishimura S, Kitamura H, Nishimura T, AsialoGM1+CD8+ central memory-type T cells in unimmunized mice as novel immunomodulator of IFN-gamma-dependent type 1 immunity. , International Immunology , 2007 , (IF:3.290)
English: Kosaka A, Lee U, Wakita D, Matsubara N, Togashi Y, Nishimura S, Kitamura H, Nishimura T., Interleukin-12-responding asialoGM1+CD8+ central memory-type T cells as precursor cells for interferon-gamma-producing killer T cells. , Cancer Science , 2006 , (IF:3.869)
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