Organization
Hospital Clinical Departments Ophthalmology
YOSHIOKA Takafumi
Degree
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博士（医学） ( 2016.3 旭川医科大学 )
Research Areas
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Life Science / Ophthalmology
Education
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Sapporo Medical University Faculty of Medicine
- 2007.4
Country： Japan
Research History
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Asahikawa Medical College Lecturer
2020.9
Studying abroad experiences
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2013.6 - 2015.6 慶應義塾大学医化学教室 特任助教
Papers
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Effect of insulin treatment on pulsatility ratio and resistance index of the retinal artery in patients with type 2 diabetes. Reviewed
Omae T, Song Y, Yoshioka T, Tani T, Yoshida A.
PLoS one 2021.7
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Deterioration of Retinal Blood Flow Parameters in Branch Retinal Vein Occlusion Measured by Doppler Optical Coherence Tomography Flowmeter. Reviewed
Takahashi K, Song Y, Sogawa K, Yoshioka T, Tani T, Ishiko S, Yoshida A.
J Clin Med. 2020.6
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Retinal blood flow reduction in normal-tension glaucoma with single-hemifield damage by Doppler optical coherence tomography. Reviewed
Yoshioka T, Song Y, Kawai M, Tani T, Takahashi K, Ishiko S, Lavinsky F, Wollstein G, Ishikawa H, Schuman JS, Yoshida A.
Br J Ophthalmol. 2020.3
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Longitudinal Changes in Retinal Blood Flow in a Feline Retinal Vein Occlusion Model as Measured by Doppler Optical Coherence Tomography and Optical Coherence Tomography Angiography. Reviewed
Wada T, Song Y, Oomae T, Sogawa K, Yoshioka T, Nakabayashi S, Takahashi K, Tani T, Ishibazawa A, Ishiko S, Yoshida A.
Invest Ophthalmol Vis Sci. 2020.2
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Retinal blood flow reduction after panretinal photocoagulation in Type 2 diabetes mellitus: Doppler optical coherence tomography flowmeter pilot study.
Song Y, Tani T, Omae T, Ishibazawa A, Yoshioka T, Takahashi K, Akiba M, Yoshida A.
PLoS One. 2018.11
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Repeatability and Reproducibility of Retinal Blood Flow Measurement Using a Doppler Optical Coherence Tomography Flowmeter in Healthy Subjects. Reviewed
Tani T, Song YS, Yoshioka T, Omae T, Ishibazawa A, Akiba M, Yoshida A.
Invest Ophthalmol Vis Sci. 2017.1
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Glial Endothelin-1 Regulates Retinal Blood Flow During Hyperoxia in Cats. Reviewed
Song Y, Nagaoka T, Yoshioka T, Ono S, Wada T, Nakabayashi S, Tani T, Yoshida A.
Invest Ophthalmol Vis Sci. 2016.9
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Evaluation of Retinal Circulation Using Segmental-Scanning Doppler Optical Coherence Tomography in Anesthetized Cats. Reviewed
Nagaoka T, Tani T, Song YS, Yoshioka T, Ishibazawa A, Nakabayashi S, Akiba M, Yoshida A.
Invest Ophthalmol Vis Sci. 2016.6
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Role of Glial Cells in Regulating Retinal Blood Flow During Flicker-Induced Hyperemia in Cats Reviewed
Youngseok Song, Taiji Nagaoka, Takafumi Yoshioka, Seigo Nakabayashi, Tomofumi Tani, Akitoshi Yoshida
Invest Ophthalmol Vis Sci. 2015.11
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Effect of intravitreal Rho kinase inhibitor ripasudil (K-115) on feline retinal microcirculation Reviewed
Nakabayashi S, Kawai M, Yoshioka T, Song YS, Tani T, Yoshida A, Nagaoka T.
Exp Eye Res. 2015.8
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Role of neuronal nitric oxide synthase in regulating retinal blood flow during flicker-induced hyperemia in cats Reviewed
Takafumi Yoshioka, Taiji Nagaoka, Youngseok Song, Harumasa Yokota, Tomofumi Tani, Akitoshi Yoshida
nvest Ophthalmol Vis Sci. 2015.5
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Role of Ca2+ -dependent and Ca2+ -sensitive mechanisms in sphingosine 1-phosphate-induced constriction of isolated porcine retinal arterioles in vitro Reviewed
Kamiya T, Nagaoka T, Omae T, Yoshioka T, Ono S, Tanano I, Yoshida A.
Exp Eye Res. 2014.4
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Autoregulation of retinal blood flow in response to decreased ocular perfusion pressure in cats: comparison of the effects of increased intraocular pressure and systemic hypotension Reviewed
Tani T, Nagaoka T, Nakabayashi S, Yoshioka T, Yoshida A.
Invest Ophthalmol Vis Sci. 2014.1
Research Projects
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質量分析イメージングによる水晶体硫黄代謝機構の解明
2019.4 - 2022.3
若手研究(B)
新規白内障マウスモデルに独自のメタボロミクス解析技術を応用することで、水晶体における代謝産物の変動を網羅的に解析し、その透明性維持機構に関わる代謝制御機構を明らかにする。具体的には代謝経路のキーレギュレーターで水晶体混濁の原因遺伝子の一つであるCystathionine-β-synthase(CBS)のノックアウトマウスを用いて定量的質量分析イメージングによるin vivo メタボロミクス解析を行うことで、マウス水晶体における硫黄代謝の変化を時空間的に解明する。
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D-OCT血流計による網膜Neurovascular Unitの評価と臨床応用
2016.4 - 2019.3
若手研究(B)
D-OCT血流計による網膜Neurovascular Unitの評価と臨床応用