Updated on 2024/12/26

写真a

 
IKEGAMI Masanaga
 
Organization
School of Medicine General Education Psychology
External link

Degree

  • 博士（行動科学） ( 2007.7   筑波大学 )

  • 修士（心理学） ( 1998.3   筑波大学 )

Research Interests

  • NIRS

  • ADHD

  • impulsivity

  • discounting

  • 注意

  • 実行機能

Research Areas

  • Life Science / Cognitive and brain science

  • Humanities & Social Sciences / Experimental psychology

Education

  • University of Tsukuba

    1996.4 - 1999.12

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    Country： Japan

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  • University of Tsukuba   Graduate School, Division of Psychology

    - 1999.12

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    Country： Japan

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  • University of Tsukuba   Second Cluster of Colleges, College of Human Sciences

    1992.4 - 1996.3

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    Country： Japan

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  • University of Tsukuba   Second Cluster of College

    - 1996.3

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    Country： Japan

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Research History

  • Asahikawa Medical College   School of Medicine   Professor

    2024.3

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    Country：Japan

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  • The Open University of Japan   Visiting Associate Professor

    2022.4 - 2023.3

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  • Asahikawa Medical College   School of Medicine   Associate Professor

    2020.12 - 2024.2

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    Country：Japan

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  • Asahikawa Medical College   School of Medicine   Lecturer

    2011.2 - 2020.12

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    Country：Japan

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  • Asahikawa Medical College   School of Medicine   Assistant Professor

    2007.4 - 2011.2

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    Country：Japan

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  • Asahikawa Medical College   School of Medicine

    2000.4 - 2007.3

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    Country：Japan

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Professional Memberships

Papers

  • Differential Neural Correlates in the Prefrontal Cortex during a Delay Discounting Task in Healthy Adults: An fNIRS Study. Reviewed International journal

    Masanaga Ikegami, Michiko Sorama

    Brain sciences   13 ( 5 )   2023.5

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    Language：English   Publishing type：Research paper (scientific journal)  

    The phenomenon of future rewards being devalued as a function of delay is referred to as delay discounting (DD). It is considered a measure of impulsivity, and steep DD characterizes psychiatric problems such as addictive disorders and attention deficit/hyperactivity disorder. This preliminarily study examined prefrontal hemodynamic activity using functional near-infrared spectroscopy (fNIRS) in healthy young adults performing a DD task. Prefrontal activity during a DD task with hypothetical monetary rewards was measured in 20 participants. A discounting rate (k-value) in the DD task was determined on the basis of a hyperbolic function. To validate the k-value, a DD questionnaire and the Barratt impulsiveness scale (BIS) were administered after fNIRS. The DD task induced a significant increase in oxygenated hemoglobin (oxy-Hb) concentration bilaterally in the frontal pole and dorsolateral prefrontal cortex (PFC) compared with a control task. Significant positive correlations were detected between left PFC activity and discounting parameters. Right frontal pole activity, however, showed significantly negative correlation with motor impulsivity as a BIS subscore. These results suggest that left and right PFCs have differential contributions when performing the DD task. The present findings suggest the idea that fNIRS measurement of prefrontal hemodynamic activity can be useful for understanding the neural mechanisms underlying DD and is applicable for assessing PFC function among psychiatric patients with impulsivity-related problems.

    DOI： 10.3390/brainsci13050758

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  • Delay Discounting of Monetary Rewards in Children with Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Reviewed

    IKEGAMI Masanaga

    Psychiatria et neurologia paediatrica japonica   60 ( 3 )   223 - 231   2020

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    Language：Japanese   Publisher：Japanese Society of Pediatric Psychiatry and Neurology  

    In humans and animals, future rewards are devalued as a function of delay. This phenomenon is referred to as delay discounting. A higher discounting rate predicts impulsive choice behavior such as a preference for small, immediate rewards. Using a delay discounting questionnaire for children, the present study examined delay discounting of monetary rewards in children with attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) to evaluate their impulsivity. A questionnaire about self-regulating behavior in daily life was also used to validate the discounting rate. Children that chose small, immediate rewards in the questionnaire about self-regulating behavior showed higher discounting rates than did children who chose larger, delayed rewards, suggesting that discounting rates are correlated with impulsive choice behavior in daily life. Children with ADHD and ASD did not differ significantly in discounting rates; however, both groups showed higher rates than did previously reported typically developing children, implying that children with ADHD and ASD tend to devalue future rewards more steeply. Discounting rates in children with ADHD, but not those with ASD, were negatively correlated with age. These results suggest that delay discounting may be useful for understanding and assessing impulsivity in children with ADHD and ASD.

    DOI： 10.24782/jsppn.60.3_223

    CiNii Books

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    Other Link： https://ndlsearch.ndl.go.jp/books/R000000004-I030689509

  • Identification of fragmented letters through minimum-distance interpolation Reviewed

    高橋, 龍尚, Yinlai, Jiang, Shuoyu, Wang, 池上, 将永, 吉村, 昭人, 宮澤, 良祐, 渡邉, 紳一, 松尾, 崇, 柳田, 裕隆

    37 ( 8 )   795 - 802   2016.8

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    Language：English   Publishing type：Research paper (scientific journal)  

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    Other Link： http://amcor.asahikawa-med.ac.jp/modules/xoonips/detail.php?id=2016090601

  • Improved prefrontal activity in AD/HD children treated with atomoxetine: a NIRS study. Reviewed International journal

    Akiko Araki, Masanaga Ikegami, Akie Okayama, Naoya Matsumoto, Satoru Takahashi, Hiroshi Azuma, Masaharu Takahashi

    Brain & development   37 ( 1 )   76 - 87   2015.1

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    Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    BACKGROUND/AIMS: Atomoxetine (ATX), a selective norepinephrine reuptake inhibitor, is the first approved non-stimulant drug for treatment of attention deficit/hyperactivity disorder (AD/HD). The present study examined the effects of long-term treatment with ATX on prefrontal hemodynamic activity in AD/HD children during a continuous performance task (CPT) using near-infrared spectroscopy (NIRS). METHODS: Prefrontal hemodynamic activity was measured in 12 children with AD/HD during experimental sessions conducted before and 6 months or more after starting ATX treatment. The average maintenance dose of ATX was 1.6 mg/kg/day. Fourteen age-matched typically developing children participated as a control group. RESULTS: In the control group, the CPT induced a significant increase in oxygenated hemoglobin (oxy-Hb) concentration in the bilateral dorsolateral prefrontal cortex (DLPFC). In the AD/HD group in the pre-ATX condition, the CPT did not induce a significant increase in oxy-Hb concentration in any of the NIRS channels, but induced a significant decrease in oxy-Hb concentration in the left ventrolateral prefrontal cortex (VLPFC). In the AD/HD group in the post-ATX condition, significant activation was observed in the right DLPFC and the decrease in oxy-Hb concentration in the left VLPFC disappeared. CONCLUSIONS: These results suggest that long-term treatment with ATX improved prefrontal hemodynamic activity in AD/HD children, and NIRS may be useful for assessment of the prefrontal hemodynamic response to ATX treatment.

    DOI： 10.1016/j.braindev.2014.03.011

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  • Quantification of the Human Ability to Identify Fragmented Letters through Visual Interpolation Reviewed

    JIANG Yinlai, IKEGAMI Masanaga, YANAGIDA Hirotaka, TAKAHASHI Tatsuhisa, WANG Shuoyu

    Transactions of Japanese Society for Medical and Biological Engineering   48 ( 4 )   369 - 376   2010.8

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    Language：English   Publisher：Japanese Society for Medical and Biological Engineering  

    To quantify a subject's skill at visual interpolation, as in the identification of incomplete letters, we developed a new computer-based system for presenting fragmented letters of the English alphabet. Using this system, we examined the quantitative relationship between the fragmentation of letters and their correct identification in six healthy young male subjects. The 26 letters (black, 72-point, MSP Gothic) were randomly displayed one by one on the screen of a personal computer: each letter appeared once per test. Each of the letters was presented within a square (128 × 128 pixels) against a white background for 200 ms. The fragmented letters were produced by randomly removing pixels from complete letters using three different modes of elimination: removal of single dots or small and large rectangles with random rotation. The complete and fragmented letters were evaluated with respect to the density of information provided by the pixels that constituted the letters according to information theory. There was a direct correlation between the percentage of pixels removed from the complete letters and the density of information about the removed pixels. The scores for the correct identification of fragmented letters with dot elimination remained at almost 100% correct identification regardless of the percentage of pixels removed. In contrast, the correct identification scores with the elimination of large rectangles decreased with the removal of 70%, 80%, 86%, 90%, and 92% of pixels. The correct identification scores for the elimination of small rectangles fell between the scores for the other elimination modes. These results suggest that the identification of fragmented letters could be related to the recognition of structures in which imaginary lines exist between closest pixels, within some limited distance between existing pixels. The evaluation of fragmented-letter identification using this system may be useful for quantifying the capability of visual interpolation.

    DOI： 10.11239/jsmbe.48.369

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    Other Link： http://search.jamas.or.jp/link/ui/2010346415

  • Effect of Age on the Human Ability to Identify Fragmented Letters through Visual Interpolation Reviewed

    Jiang, Yinlai, Ikegami, Masanaga, Yanagida, Hirotaka, 高橋, 龍尚, Wang, Shuoyu

    Therapeutic Research   31 ( 7 )   1049 - 1055   2010.7

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  • Theoretical analysis of oxygen consumption by vascular walls exposed to hemodynamic stress in the human retinal microvascular network Reviewed

    Tatsuhisa Takahashi, Akiyoshi Okada, Tadashi Saitoh, Masanaga Ikegami, Hirotaka Yanagida

    Transactions of Japanese Society for Medical and Biological Engineering   48 ( 5 )   482 - 493   2010

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    Publishing type：Research paper (scientific journal)  

    The rates at which endothelial and smooth muscle cells in vessel walls should consume oxygen during blood transport along the length of a microvascular network are highly controversial. We examined the arteriovenous distribution of oxygen consumption by a microvesselwallexposed to circumferentialwallstress and fluid shear stress. A model of retinal microcirculation in which a network that branched dichotomously at every bifurcation depended on both a flow conservation law and a modified Murray's law with a diameter exponent of 2.85 was used. Oxygen consumption was calculated from the integration of the number of branches multiplied by the consumption rates of the endothelial and smooth muscle cells per branch unit. The oxygen consumption by all of the microvessel walls was only about 1.9% of the totaloxygen consumption throughout the microvascular network, including the surrounding tissues. This result suggests that the oxygen that had diffused across the microvessel walls was mainly consumed by the surrounding tissues. Also, based on the circumferential and shear stresses, the microvascular flow and pressure control system is presumably designed to optimize the vessel tone of the arteriolar network so that the microcirculation can accommodate material exchange.

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  • Differential frontal activation during exogenous and endogenous orientation of visuospatial attention. A near-infrared spectroscopy study. Reviewed International journal

    Masaharu Takahashi, Masanaga Ikegami

    Neuropsychobiology   58 ( 2 )   55 - 64   2008

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    Language：English   Publishing type：Research paper (scientific journal)  

    AIMS: The aim was to measure the prefrontal cortical activity involved in shifting spatial attention to visual stimuli in the left or right visual field using near-infrared spectroscopy. METHODS: Eleven participants performed a simple vigilance task, an endogenous attention task and an exogenous attention task. In the endogenous task, the left or the right side of the center diamond brightened, indicating the side for subsequent target appearance (controlled shift of attention). In the exogenous task, the peripheral squares brightened, indicating the appearance of target in those squares (reflexive shift of attention). RESULTS: Stimuli at validly cued locations were responded to faster than stimuli at invalidly cued locations. Increases in oxyhemoglobin (oxy-Hb) were observed in the right prefrontal cortex throughout the 3 tasks, and in the left prefrontal cortex during the vigilance and the exogenous tasks. In the exogenous task, marked decreases in oxy-Hb were observed in the bilateral ventrolateral prefrontal cortex. CONCLUSIONS: These results suggest that the left and the right prefrontal cortices mediate distinct cognitive processes during the performance of visuospatial attentional tasks.

    DOI： 10.1159/000159773

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  • 新生仔期6-hydroxydopamine処置ラットの行動特性における残存dopamine作動性神経系の役割. 筑波大学博士論文

    池上将永

    2007.7

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    Language：Japanese   Publishing type：Thesis (other)  

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  • Compensatory increase in extracellular dopamine in the nucleus accumbens of adult rats with neonatal 6-hydroxydopamine treatment. Reviewed

    Masanaga Ikegami, Yukio Ichitani, Tatsuhisa Takahashi, Tsuneo Iwasaki

    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology   26 ( 3 )   111 - 7   2006.6

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    To characterize a compensatory function of the dopaminergic system of residual dopamine (DA) neurons in the mesolimbic pathway with DA-depleting lesions, we compared tissue and extracellular concentrations of DA and its metabolites in the nucleus accumbens (NACC) of adult rats with neonatal 6-hydroxydopamine (6-OHDA) treatment with those of control rats with neonatal vehicle treatment using high-performance liquid chromatography. The tissue concentration of DA for 6-OHDA-treated rats was 26.9% of that for the control rats, whereas the extracellular DA was not significantly different from the controls. Furthermore, the extracellular DA concentration in the NACC of 6-OHDA-treated rats was significantly increased compared to the controls following neurotensin (NT) microinjection into the ventral tegmental area (VTA). These results suggest that the extracellular DA of the adult rat brain following neonatal 6-OHDA treatment was compensated for by increasing the release of DA from terminals in the NACC of remaining DA neurons through increased mesolimbic pathway afferents (increased demand), as well as by decreasing the synaptic DA reuptake sites and/or D4 receptors. This study supports our hypothesis that the compensatory mechanism(s) of remaining DA neurons in the mesolimbic system are underlying in behavioral characteristics of adult rats with neonatal depletion of brain DA.

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  • [Effects of neurotensin microinjected into ventral tegmental area on spontaneous motor activity in neonatal 6-hydroxydopamine-treated rats]. Reviewed

    Masanaga Ikegami, Tsuneo Iwasaki

    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology   24 ( 2 )   83 - 5   2004.4

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

    Intracerebroventricular treatment of the catecholamine neurotoxin, 6-hydroxydopamine (6-OHDA) after desmethylimipramine pretreatment results in semipermanent brain dopamine (DA) depletion. It has been shown that rats neonatally treated with 6-OHDA show hyperactivity in an open-field test. The purpose of this study was to investigate the spontaneous motor activity in neonatal 6-OHDA-treated rats following bilateral saline (SAL; 0.25 microliter) or neurotensin (NT; 1.25, 2.50, 5.00 micrograms/0.25 microliter/side) microinjection into the ventral tegmental area. Each dose of NT significantly augmented locomotor activity in 6-OHDA-treated rats. On the other hand, controls did not show significant increase in lower dose of NT. Effect of NT microinjection on number of rearings in the 6-OHDA-treated group was not significantly altered compared to the vehicle-treated group. These results suggest that the responses in locomotor activity to NT the ventral tegmental area increase in neonatal 6-OHDA-treated rats, and imply that residual activity in mesolimbic DA neurons which is mediated by NT receptors contributes to a part of the hyperactivity seen after neonatal 6-OHDA lesion.

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  • 新生仔期脳内6-hydroxydopamine処置ラットの一般活動性に及ぼすneurotensin腹側被蓋野内投与の効果 Reviewed

    池上将永, 岩崎庸男

    日本神経精神薬理学雑誌   24   83 - 85   2004.4

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    Authorship：Lead author   Language：Japanese   Publishing type：Research paper (scientific journal)  

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  • 注意欠陥多動性障害の動物モデルに関する研究動向 Reviewed

    池上, 将永

    旭川医科大学研究フォーラム   創刊号   48 - 59   2000.12

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    Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：旭川 : 旭川医科大学  

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    Other Link： http://id.ndl.go.jp/bib/5845821

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Books

  • セルフ・コントロールの心理学：自己制御の基礎と教育・医療・矯正への応用

    池上将永（ Role： Contributor第17章「衝動性とセルフ・コントロールの神経基盤」pp.290-312.）

    北大路書房  2017.5  （ ISBN:9784762829734 ）

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  • 生命倫理事典

    池上将永（ Role： Contributor「発達障害」pp.745-747）

    太陽出版  2010.3  （ ISBN:9784884696672 ）

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Presentations

  • The Utility of Delay Discounting Tests in ADHD Cognitive Behavioral Assessment Battery: A Preliminary Study in a Non-clinical Group

    Masanaga Ikegami, Michiko Sorama, Aya Katayama, Hidetoshi Omiya

    Society for the Quantitative Analysis of Behavior 46th Annual Meeting  2024.5 

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    Event date： 2024.5

    Language：English   Presentation type：Poster presentation  

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  • 音読・歌唱およびハミング課題遂行中の前頭前皮質活動 －近赤外分光法（NIRS）を用いた検討－

    池上将永, 高橋雅治

    日本心理学会第86回大会 

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    Event date： 2022.9

    Language：Japanese   Presentation type：Poster presentation  

    Venue：日本大学文理学部  

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  • Prefrontal hemodynamic activity during reading, singing and humming tasks: A near-infrared spectroscopy study

    Ikegami Masanaga, Takahashi Masaharu

    The Proceedings of the Annual Convention of the Japanese Psychological Association  2022  The Japanese Psychological Association

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    Event date： 2022

    Language：Japanese  

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  • 発達障害の心理学的基礎研究と医療との連携

    池上将永

    北海道心理学会第66回大会 

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    Event date： 2019.10

    Language：Japanese   Presentation type：Symposium, workshop panel (nominated)  

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  • 芸術的風景写真映像による高齢者の心理的生理的変化について

    牧野志津, 池上将永, 中田真依, 中西敏貴, 大坪智美, 野中雅人, 守屋潔, 服部ユカリ

    日本応用老年学会大会  2019 

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    Event date： 2019

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  • ADHD児とASD児における遅延割引率の測定 －簡易版遅延割引質問紙を用いた検討－

    池上将永, 荒木章子, 空間美智子, 佐伯大輔, 奥村香澄, 高橋雅治

    日本心理学会第82回大会 

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    Event date： 2018.9

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東北大学  

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  • Delay discounting of monetary rewards in children with ADHD and autism spectrum disorders

    Ikegami Masanaga, Araki Akiko, Sorama Michiko, Saeki Daisuke, Okumura Kasumi, Takahashi Masaharu

    The Proceedings of the Annual Convention of the Japanese Psychological Association  2018.9  The Japanese Psychological Association

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    Event date： 2018.9

    Language：Japanese  

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    Other Link： https://search.jamas.or.jp/link/ui/2019005149

  • Prefrontal hemodynamic activity during delay discounting task: A near-infrared spectroscopy study

    Ikegami Masanaga, Saeki Daisuke, Sorama Michiko, Takahashi Masaharu

    The Proceedings of the Annual Convention of the Japanese Psychological Association  2017.9  The Japanese Psychological Association

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    Event date： 2017.9

    Language：Japanese  

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    Other Link： https://search.jamas.or.jp/link/ui/2018146609

  • 近赤外分光法を用いた注意欠如／多動性障害の診断補助システムの開発

    池上将永

    第94回旭川医科大学フォーラム  旭川医科大学

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    Event date： 2015.7

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：旭川市  

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  • fNIRSを用いたAtomoxetine長期内服による治療効果の評価

    荒木章子, 池上将永

    臨床神経生理学  2015 

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    Event date： 2015

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  • NIRSを用いた注意欠如／多動性障害の前頭前野機能の計測

    池上将永

    北海道心理学会第61回大会 

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    Event date： 2014.11

    Language：Japanese   Presentation type：Symposium, workshop panel (nominated)  

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  • セルフ・コントロールと衝動性の神経基盤

    池上将永

    日本行動分析学会第32回年次大会 

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    Event date： 2014.6

    Language：Japanese   Presentation type：Symposium, workshop panel (nominated)  

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  • Basic and Applied Studies on Self-Control and Discounting

    Hiraokah,Kyoichi, Takahashi,Masaharu, Ikegami,Masanaga, Sorama,Michiko, Murai,Keiko, Saeki,Daisuke

    2014.6 

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    Event date： 2014.6

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  • Atomoxetineを投与したADHD児における持続注意課題下での前頭前皮質Oxy-Hb変化-近赤外線分光法による検討-

    荒木章子, 池上将永, 坂倉真実, 岡山亜貴恵, 山本志保

    日本小児精神神経学会プログラム・抄録集  2014 

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    Event date： 2014

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  • Prefrontal hemodynamic activity in ADHD children treated with atomoxetine: A near-infrared spectroscopy study

    IKEGAMI Masanaga, ARAKI Akiko, TAKAHASHI Masaharu

    The Proceedings of the Annual Convention of the Japanese Psychological Association  2013.9  The Japanese Psychological Association

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    Event date： 2013.9

    Language：Japanese  

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  • 中高年における食事管理の自己効力感とソーシャル・サポート

    高橋雅治, 池上将永

    日本心理学会大会発表論文集  2013 

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    Event date： 2013

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  • Atomoxetine を投与したAD/HD 児におけるCPT 下での前頭前皮質Oxy-Hb 変化の検討

    荒木章子, 池上将永他

    第54回日本小児神経学会 

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    Event date： 2012.5

    Language：Japanese   Presentation type：Oral presentation (general)  

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  • 欲求不満状況における前頭前野活動の計測

    池上将永, 高橋雅治

    日本心理学会第75回大会 

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    Event date： 2011.9

    Language：Japanese   Presentation type：Poster presentation  

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  • Decreased prefrontal activation related to reward frustration: A near-infrared spectroscopy study

    IKEGAMI Masanaga, TAKAHASHI Masaharu

    The Proceedings of the Annual Convention of the Japanese Psychological Association  2011.9  The Japanese Psychological Association

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    Event date： 2011.9

    Language：Japanese  

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  • 持続注意課題を用いたAD／HD 治療薬の客観的効果判定

    荒木章子, 池上将永他

    第53回日本小児神経学会 

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    Event date： 2011.5

    Language：English   Presentation type：Oral presentation (general)  

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  • 2型糖尿病入院患者の性格特性と治療効果

    高橋雅治, 安孫子亜津子, 池上将永, 伊藤博史, 中村知伸, 羽田勝計

    糖尿病  2011 

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    Event date： 2011

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  • 人間の視覚補間による断片文字の認知力の定量化

    JIANG Yinlai, 池上将永, 柳田裕隆, 高橋龍尚, WANG Shuoyu

    生体・生理工学シンポジウム論文集  2010 

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    Event date： 2010

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  • 注意課題における子供と大人の前頭前野活動－近赤外線分光法による分析－

    高橋 雅治, 池上 将永

    日本心理学会大会発表論文集  2009.8  公益社団法人 日本心理学会

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    Event date： 2009.8

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  • 言語流暢性課題における若年者と高齢者の前頭前野活動－近赤外線分光法による分析－

    池上 将永, 高橋 雅治

    日本心理学会大会発表論文集  2009.8  公益社団法人 日本心理学会

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    Event date： 2009.8

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  • 注意課題における子供と大人の前頭前野活動

    高橋 雅治, 池上 将永

    日本心理学会第73回大会 

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    Event date： 2009.8

    Language：Japanese   Presentation type：Poster presentation  

    Venue：京都  

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  • 言語流暢性課題における若年者と高齢者の前頭前野活動

    池上 将永, 高橋 雅治

    日本心理学会第73回大会 

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    Event date： 2009.8

    Language：Japanese   Presentation type：Poster presentation  

    Venue：京都  

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  • 近赤外分光法による自閉症児の脳機能計測―Posner課題による検討―

    高橋 雅治, 池上 将永, 荒木 章子, 田中 肇

    日本心理学会大会発表論文集  2008.9  公益社団法人 日本心理学会

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    Event date： 2008.9

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  • 近赤外分光法による自閉症児の脳機能計測

    高橋雅治, 池上将永, 荒木章子, 田中肇

    日本心理学会第72回大会 

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    Event date： 2008.9

    Language：Japanese   Presentation type：Poster presentation  

    Venue：北海道  

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  • 近赤外分光法による注意欠陥/多動性障害児の脳機能計測（２）－Posner課題による検討－

    高橋 雅治, 池上 将永, 荒木 章子, 田中 肇

    日本心理学会大会発表論文集  2007.9  公益社団法人 日本心理学会

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    Event date： 2007.9

    Language：Japanese  

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  • 近赤外分光法による注意欠陥/多動性障害児の脳機能計測（１）－連続遂行課題を用いた検討－

    池上 将永, 高橋 雅治, 荒木 章子, 田中 肇

    日本心理学会大会発表論文集  2007.9  公益社団法人 日本心理学会

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    Event date： 2007.9

    Language：Japanese  

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  • 近赤外分光法による注意欠陥/多動性障害児の脳機能計測（２）

    高橋雅治, 池上将永, 荒木章子, 田中肇

    日本心理学会第71回大会 

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    Event date： 2007.9

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京  

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  • 近赤外分光法による注意欠陥/多動性障害児の脳機能計測（１）

    池上将永, 高橋雅治, 荒木章子, 田中肇

    日本心理学会第71回大会 

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    Event date： 2007.9

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京  

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  • 近赤外線分析法と持続的遂行課題を用いたADHDの評価に関する検討

    荒木章子, 池上将永, 鈴木菜生, 大日向純子, 高橋悟, 田中肇, 高橋雅治, 藤枝憲二

    第49回日本小児神経学会 

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    Event date： 2007.7

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：大阪  

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  • 近赤外線分析法と持続的遂行課題を用いたAD/HDの前頭葉機能評価

    荒木章子, 池上将永, 鈴木菜生, 大日向純子, 高橋悟, 田中肇, 藤枝憲二, 高橋雅治

    脳と発達  2007 

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    Event date： 2007

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  • 強化確率の操作が感情状態および前頭前野活動に及ぼす影響ー近赤外分光法（NIRS）による検討ー

    池上 将永, 高橋 雅治

    日本心理学会大会発表論文集  2006.11  公益社団法人 日本心理学会

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    Event date： 2006.11

    Language：Japanese  

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  • 強化確率の操作が感情状態および前頭前野活動に及ぼす影響.

    池上 将永, 高橋 雅治

    日本心理学会第70回大会 

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    Event date： 2006.11

    Language：Japanese   Presentation type：Poster presentation  

    Venue：福岡  

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  • 視空間的注意の外発的及び内発的定位と前頭前野活動

    高橋 雅治, 池上 将永

    日本心理学会第70回大会 

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    Event date： 2006.11

    Language：Japanese   Presentation type：Poster presentation  

    Venue：福岡  

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  • 空間的注意課題遂行時の前頭葉活動

    池上 将永, 高橋 雅治

    日本心理学会第69回大会 

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    Event date： 2005.9

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京  

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  • オペラント課題遂行中の前頭前野活動

    高橋 雅治, 池上 将永

    日本心理学会第69回大会 

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    Event date： 2005.9

    Language：Japanese   Presentation type：Poster presentation  

    Venue：東京  

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  • オペラント課題遂行中の前頭葉活動-連続強化スケジュールと定間隔強化スケジュールの比較-

    高橋雅治, 池上将永

    日本心理学会大会発表論文集  2005 

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    Event date： 2005

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  • 他者動作観察時の運動野活動

    高橋 雅治, 池上 将永

    日本心理学会第68回大会 

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    Event date： 2004.9

    Language：Japanese   Presentation type：Poster presentation  

    Venue：大阪  

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  • 近赤外分光法を用いた脳機能の計測

    池上 将永

    日本ME学会北海道支部第25回研究会 

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    Event date： 2004.4

    Language：Japanese   Presentation type：Oral presentation (general)  

    Venue：北海道  

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  • 注意移動課題遂行時の頭頂葉活動

    池上 将永, 高橋 雅治

    日本心理学会第68回大会 

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    Event date： 2004.4

    Language：Japanese   Presentation type：Poster presentation  

    Venue：大阪  

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  • 注意移動課題遂行時の前頭葉活動

    池上将永

    日本心理学会大会発表論文集, 2004  2004 

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    Event date： 2004

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  • 光トポグラフィーと3次元MRI画像を用いた脳機能の研究 (4)-視覚的注意課題遂行時の頭頂葉活動-

    池上将永, 高橋雅治

    日本心理学会大会発表論文集  2003 

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    Event date： 2003

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  • 光トポグラフィーと3次元MRI画像を用いた脳機能の研究 (3) 視覚的注意課題遂行時の後頭葉活動

    池上将永, 高橋雅治, 佐久間博敏

    日本心理学会大会発表論文集  2002 

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    Event date： 2002

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  • Effects of injection of neurotensin into ventral tegmental area on motor activity in neonatal 6-hydroxydopamine-treated rats

    IKEGAMI Masanaga, IWASAKI Tsuneo

    1999.12 

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    Event date： 1999.12

    Language：Japanese  

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  • Effects of neurotensin microinjected into ventral tegmental area on extracellular dopamine in nucleus accumbens in neonatal 6-hydroxydopamine-treated rats

    IKEGAMI Masanaga, IWASAKI Tsuneo

    1998.12 

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    Event date： 1998.12

    Language：Japanese  

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Research Projects

  • 多次元衝動性検査の開発とADHD診断補助への応用

    Grant number：22K03207  2022.4 - 2025.3

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    池上 将永, 高橋 雅治, 空間 美智子, 片山 綾

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    Grant amount：\2,860,000 （ Direct Cost: \2,200,000 、 Indirect Cost：\660,000 ）

    衝動性（impulsivity）は、注意欠如・多動症（ADHD）等の病態理解において中核となる心理学的概念である。衝動性は多次元的な心理・行動特性であるとされており、個人の衝動性を正確に把握するためには、各次元に対応した行動課題を用いる必要がある。本研究は、衝動性を構成する複数の次元を評価する包括的なパッケージプログラム（多次元衝動性検査）を開発することを目的としている。2022年度においては、先行研究に基づいて、衝動性を測定する行動課題として妥当性の高いものを選定し、また必要に応じて新たに行動課題を作成することが目標であった。市販の実行機能課題プログラム（CANTAB）の中から、衝動性の各次元を代表する行動課題を選定し、動作を確認するとともに、新たに遅延割引を測定するためのプログラムを作成した。これらのプログラムの組み合わせによって、衝動性の各次元を行動的に測定するための環境が構築された。また、遅延割引の認知神経科学的基盤について、NIRSを用いた研究を行った。遅延割引は、選択行動における衝動性を予測する指標であるため、その神経学的基盤を理解することは重要である。研究の結果、健常な成人が遅延割引課題を遂行しているときの前頭前皮質活動の特徴が把握された。また、遅延割引率の個人差が左背外側部の活動と相関すること、加えて、反応抑制に関わる運動衝動性の個人差が右前頭極の活動と相関することが確認された。この結果は、異なる次元の衝動性が別の神経基盤を有することを示唆しており、多次元的な衝動性測定の必要性が認知神経科学的な観点から支持された。この研究成果は、Brain Sciences誌に掲載される予定である（2023年5月1日受理）。

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  • Evaluation system of humanitude based on behavior analysis of caring behavior

    Grant number：19K03378  2019.4 - 2023.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Takahashi Masaharu

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    Grant amount：\2,340,000 （ Direct Cost: \1,800,000 、 Indirect Cost：\540,000 ）

    The present study analyzed previous studies investigating effects of 4 techniques consisting humanitude, i.e. looking, talking, touching, and raising. The results showed that there has been little quantitative research investigating effects of these 4 techniques on caregivers and care recipients and behaviors of caregivers and care recipients can be described as operant behaviors. Therefore, it was suggested that it is needed to describe behaviors of humanitude caregivers and care recipients as operant behavior and construct a model describing interactions of these operant behaviors.

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  • Does Fine Art Photo Media contribute to "KANDO" and health of the elderly?

    Grant number：16K15950  2016.4 - 2019.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Challenging Exploratory Research

    Hattori Yukari, NAKANISHI Toshiki, MORIYA Kiyoshi, MAKINO Shizu, OTUBO Tomomi, NONAKA Masato, HAGA Hiroshi

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    Grant amount：\2,080,000 （ Direct Cost: \1,600,000 、 Indirect Cost：\480,000 ）

    We created The visual media (Fine Art Photo Media: FAPM) consisting of artistic landscape photographs.FAPM were compared with the control video. As a result, FAPM not only evokes beauty and preference but also evokes past memories and interests, reduces negative moods such as anger, depression, fatigue and tension, and makes it a positive mood such as stability and vitality. It was suggested that 4 minutes and 30 seconds could be short to bring about changes in physiological indicators.

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  • Development of ADHD diagnostic aid system based on the dual pathway model

    Grant number：15K04179  2015.4 - 2018.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Ikegami Masanaga, ARAKI Akiko

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    Grant amount：\4,680,000 （ Direct Cost: \3,600,000 、 Indirect Cost：\1,080,000 ）

    The present study examined the delay discounting as a measure of impulsivity in children with ADHD and autism spectrum disorders (ASD), using a delay discounting questionnaire. We also investigated the relationship between the impulsivity and frontal hemodynamic activities during the delay discounting task using near-infrared spectroscopy (NIRS). The obtained results can be summarized as follows: (1) children with ADHD and ASD showed higher delay discounting rates than typically developing children. (2) In the healthy adolescents, the delay discounting task produced significant activities in the dorsolateral prefrontal cortex (DLPFC). (3) ADHD adolescents treated with pharmacological therapy also showed prefrontal activities during the task. These findings suggest that neuropsychological examination using delay discounting task and NIRS may be useful for diagnosis of ADHD and assessment of the prefrontal hemodynamic response to pharmacological treatments.

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  • A model of relationships between psychological factors regarding self-care for life-style related deseases

    Grant number：15K04178  2015.4 - 2018.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Takahashi Masaharu

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    Grant amount：\2,730,000 （ Direct Cost: \2,100,000 、 Indirect Cost：\630,000 ）

    A model of the hypothesized relationships between psychological factors regarding self-care (general self-efficacy, self-control, social support and self-efficacy regarding self-care) was tested in young heathy and elder healthy participants using structural equation modeling (SEM). For young participants, general self-efficacy had a direct association with self-control and self-control had a direct association with self-efficacy regarding self-care. For elder participant, however, general self-efficacy had a direct association with social support and social support had a direct association with self-efficacy regarding self-care. In sum, young people with high self-efficacy tend to show high self-control resulting in good self-care whereas elder people with high self-efficacy have high social support resulting in good self-care. It was suggested different interventions for self-care are needed for young and elder people.

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  • 近赤外分光法を用いた注意欠如／多動性障害の診断補助法の確立

    2014.10 - 2015.9

    旭川医科大学 

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  • 近赤外分光法を用いた注意欠如／多動性障害の診断補助システムの開発

    2013.10 - 2014.9

    旭川医科大学 

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  • A study of individual differences in coping strategies with reward frustration.

    Grant number：21730583  2009 - 2010

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (B)

    IKEGAMI Masanaga

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    Grant amount：\1,820,000 （ Direct Cost: \1,400,000 、 Indirect Cost：\420,000 ）

    The present study aimed at examining the relationship between coping strategies and frontal activities in reward frustration. The results obtained suggested that (1) frustration induced by effort-reward imbalance decreased reactivitiy in the dorsolateral prefrontal cortex in both hemispheres, (2) neuroticism negatively correlated with oxy-Hb increases in the right dorsolateral prefrontal cortex during the frustration task, (3) subjective degree of concentration to the task positively correlated with oxy-Hb increases in the dorsolateral prefrontal cortex in both hemispheres.

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  • Development and application of self-control scales which are really useful to medicine and education

    Grant number：20330147  2008 - 2011

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

    TAKAHASHI Masaharu, IKEGAMI Masanaga, KAMAKURA Yayoi, FUKADA Junko, MOMOSE Yumiko, SAKAGAMI Takayuki, ITOU Masato, SAEKI Daisuke, HIRAOKA Hiraoka, AOYAMA Kenjiro

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    Grant amount：\20,800,000 （ Direct Cost: \16,000,000 、 Indirect Cost：\4,800,000 ）

    In the educational field, we developed a test of delay discounting for schoolchildren and university students. Rates of discounting in schoolchildren are correlated with learning performances in mathematics and could be improved by educational interventions. Similarly, rates of discounting in university students were correlated with their learning attitudes and high discounting rates predicted less time in writing research papers. In the medical field, patients with type II diabetes mellitus who showed low scores in sensation seeking scales showed high HbA1c after discharging. Moreover, we developed a self-control scale for health behavior and showed that high scores of the scale predicted better oral cares in elder healthy people and more faithful observances of medications and dietary cures in chronic kidney disease.

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  • フラストレーション状況における大脳皮質活動に関する研究

    Grant number：16730365  2004 - 2005

    日本学術振興会  科学研究費助成事業  若手研究(B)

    池上 将永

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    Grant amount：\1,200,000 （ Direct Cost: \1,200,000 ）

    本研究ではフラストレーション状況におけるヒトの前頭前野の活動を検討するために、実験的なフラストレーション状況を設定し、実験課題遂行中の被験者の行動反応、および前頭葉における局所脳血流の変化を近赤外分光法(near-infrared spectroscopy ; NIRS)を用いて計測した。
    平成17年度では、成人男女のべ33名を被験者として、視覚的注意課題、オペラント課題、および反応時間課題を遂行しているときの前頭葉の局所脳血流の変化をNIRS装置を用いて検証した。反応時間課題では、ターゲット検出までの反応時間および反応の正確性について、被験者は試行ごとに評価され報酬ポイントが与えられた。反応時間課題の前半セッションでは、反応時間に応じて一定の評価が与えられ目標指向行動は円滑であった。その際の前頭葉では、広い範囲で酸素化ヘモグロビン(oxy-Hb)の増加が認められ、課題遂行に伴う前頭前野の賦活が示唆された。一方、後半セッションでは、反応時間に関わらず評価を伴わない試行が複数含まれており、努力に見合った報酬が得られないというフラストレーション状況であった。被験者の反応時間は前半セッションに比べて有意に短縮され、報酬獲得に対する動機づけが高まっていることが示唆された。また、セッション終了後の質問紙(Attention-Affect Check List ; AACL)を用いた主観報告では「苛立ち」のポイントが有意に増加しており、被験者がフラストレーションを感じていることが示唆された。さらに、後半セッション遂行時の前頭前野では一部でoxy-Hbの減少が認められ、課題依存的な"deactivation"が生じていることが明らかとなった。本研究の結果から、フラストレーション状況においては、前頭前野の活動パターンが円滑な目標指向行動が行われている状況とは異なっており、事態の評価、動機づけ、情動反応の生成や制御を反映した変化が生じていることが示唆された。

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  • 心理的仮想現実感を実現する基礎技術の開発

    Grant number：13224002  2001

    日本学術振興会  科学研究費助成事業  特定領域研究(C)

    高橋 雅治, 池上 将永

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    本年度は、聴覚的な情報処理に伴って生じる主観的な体験を物理的な刺激の操作により再現する技術を開発するための心理物理学的研究、及び、情報処理の個人差に関する脳科学研究を行った。
    前者の心理物理学実験では、研究代表者の開発した「選択的聴取を行動的に測定する装置」を装着した状態で、文章朗読刺激を聴取し、その内容を記憶する行動実験を行った。被験者は、実験後に、装着した装置に組み込まれている「注意集中に伴う聞こえの変化関数」の自然さを評価した。そして、その結果得られた注意集中の個人差を「選択的聴取を行動的に測定する装置」のシステムに組み込むことにより、他者の主観的な聞こえの世界を体験する「心理的な仮想現実技術」を開発した。
    一方、後者の脳科学実験では、文章刺激を聞いている時の被験者の脳活動を光トポグラフィー測定装置を用いて測定し、情報処理の個人差を脳活動のレベルで解明することを目的として行われた。具体的には、文章朗読刺激を聴取している場合の脳活動を測定し、その結果を被験者の主観的な体験の個人差と照合することにより、仮想現実場面において情報処理の個人差を分類することが試みられた。脳活動の測定装置としては、光トポグラフィー装置、及び、脳血流量の変化が実際に脳のどの部位のデータであるかを被験者のMRIによる脳画像と重ねるためのシステムが用いられた。その結果、聴覚刺激を用いた同一の課題であったも被験者により異なる脳活動を示すことが示唆された。

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Social Activities

  • 放送大学公開講演会 「脳の仕組みと認知アセスメントで理解する発達障害の特徴」

    2023.2

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    第31回 旭川生涯学習フェア「まなびピアあさひかわ」参加事業

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  • 派遣講座 喜怒哀楽の科学（永山公民館百寿大学）

    2022.10

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  • 派遣講座 喜怒哀楽の科学（北海道栄養士会留萌支部）

    2021.4

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  • 派遣講座 喜怒哀楽の科学（神居公民館女性大学）

    2019.6

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  • 派遣講座 喜怒哀楽の科学（愛宕公民館あたご市民大学）

    2019.1

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  • 北海道栄養士会旭川支部 すこやか北海道研修会

    2018.9

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  • 派遣講座 喜怒哀楽の科学（北星公民館百寿大学）

    2018.7

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  • 派遣講座 喜怒哀楽の科学（東鷹栖しののめ大学）

    2017.9

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  • 派遣講座 喜怒哀楽の科学（東鷹栖公民館百寿大学）

    2017.9

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  • 派遣講座 喜怒哀楽の科学（雨竜町）

    2016.11

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    平成28年11月10日（木）

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  • 派遣講座 喜怒哀楽の科学（神居公民館）

    2016.7

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    平成28年7月20日（水）

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  • 派遣講座 喜怒哀楽の科学（神楽公民館）

    2015.9

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    平成27年9月11日（金）

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  • 派遣講座 喜怒哀楽の科学（神居公民館）

    2015.1

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  • 派遣講座 喜怒哀楽の科学（新旭川公民館）

    2014.7

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  • 派遣講座 喜怒哀楽の科学（旭川シニア大学）

    2013.10

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Academic Activities

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  • Scientific Reports査読者 International contribution

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