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English: A. Yasuda, W. Murase, A. Kubota, N. Uramaru, K. Okuda, R. Hakota, A. Ikeda, H. Kojima, Effects of di-(2-ethylhexyl) phthalate and its metabolites on transcriptional activity via human nuclear receptors and gene expression in HepaRG cells , Toxicology in Vitro , vol.101 (p.105943 - ) , 2024 , (IF:2.6)
English: Y, Takahashi, M. Asari, S. Isozaki, C. Hoshina, K. Okuda, K. Mori, R. Namba, W. Ochiai, K. Shimizu, Age prediction by methylation analysis of small amounts of DNA using locked nucleic acids , Journal of Forensic Sciences , vol.68 (p.267 - 274) , 2023 , (IF:1.717)
English: K. Okuda, S. Isozaki, M. Asari, H. Tanaka, K. Horioka, Y. Takahashi, C. Hoshina, H. Yamada, K. Mori, R. Namba, H. Shiono, K. Ogawa, K. Shimizu, Multidirectional analysis for a colchicine poisoning case revealed detail cause of death and its mechanism , Legal Medicine , vol.58 , 2022 , (IF:2.017)
English: Horioka Kie, Tanaka Hiroki, Isozaki Shotaro, Konishi Hiroaki, Fujiya Mikihiro, Okuda Katsuhiro, Asari Masaru, Shiono Hiroshi, Ogawa Katsuhiro, Shimizu Keiko, Acute Colchicine Poisoning Causes Endotoxemia via the Destruction of Intestinal Barrier Function: The Curative Effect of Endotoxin Prevention in a Murine Model. , Dig Dis Sci , vol.65 (1) (p.132 - 140) , 2020 , (IF:2.937)
English: Horioka Kie, Tanaka Hiroki, Isozaki Shotaro, Okuda Katsuhiro, Asari Masaru, Shiono Hiroshi, Ogawa Katsuhiro, Shimizu Keiko, Hypothermia-induced activation of the splenic platelet pool as a risk factor for thrombotic disease in a mouse model. , J Thromb Haemost , vol.17 (10) (p.1762 - 1771) , 2019 , (IF:4.662)
English: Tanaka Hiroki, Horioka Kie, Yamamoto Masahiro, Asari Masaru, Okuda Katsuhiro, Yamazaki Kosuke, Shimizu Keiko, Ogawa Katsuhiro, Overproduction of thrombopoietin by BRAFV600E-mutated mouse hepatocytes and contribution of thrombopoietin to hepatocarcinogenesis. , Cancer Sci , vol.110 (9) (p.2748 - 2759) , 2019 , (IF:4.751)
English: Asari Masaru, Isozaki Shotaro, Hoshina Chisato, Okuda Katsuhiro, Tanaka Hiroki, Horioka Kie, Shiono Hiroshi, Shimizu Keiko, Discrimination of haplotype in mitochondrial DNA mixtures using LNA-mediated PCR clamping. , Forensic Sci Int Genet , vol.41 (p.58 - 63) , 2019 , (IF:4.884)
English: M. Hirao-Suzuki, S. Takeda, K. Okuda, M. Takiguchi, S. Yoshihara, Repeated exposure to 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene (MBP), an active metabolite of bisphenol A, aggressively stimulates breast cancer cell growth in an estrogen receptor β (ERβ)-dependent manner. , Mol. Pharmacol. , vol.95 (p.260 - 268) , 2019 , (IF:3.978)
English: H. Kojima, S. Takeuchi, S. Sanoh, K. Okuda, S. Kitamura, N. Uramaru, K. Sugihara, K. Yoshinari, Profiling of bisphenol A and eight its analogues on transcriptional activity via human nuclear receptors. , Toxicology , vol.413 (p.48 - 55) , 2019 , (IF:3.265)
English: Takaoka N, Sanoh S, Okuda K, Kotake Y, Sugahara G, Yanagi A, Ishida Y, Tateno C, Tayama Y, Sugihara K, Kitamura S, Kurosaki M, Terao M, Garattini E, Ohta S., Inhibitory effects of drugs on the metabolic activity of mouse and human aldehyde oxidases and influence on drug–drug interactions , Biochemical Pharmacology , vol.154 (p.28 - 38) , 2018 , (IF:4.581)
English: H. Tanaka, K. Okuda, S. Ohtani, M. Asari, K. Horioka, S. Isozaki, A. Hayakawa, K. Ogawa, S. Hiroshi, K. Shimizu, Chained nuclei and python pattern in skeletal muscle cells as histological markers for electrical injury , Leg Med , vol.32 (p.75 - 78) , 2018 , (IF:1.254)
English: S. Hanaoka, K. Ishida, S. Tanaka, S. Sakamoto, K. Okuda, S. Sanoh, S. Ohta, Y. Kotake, Tributyltin induces epigenetic changes and decreases the expression of nuclear respiratory factor-1 , Metallomics , vol.10 (p.337 - 345) , 2018 , (IF:3.975)
English: C. Hoshina, T. Omura, K. Okuda, H. Tanaka, M. Asari, S. Isozaki, K. Horioka, H. Yamada,H. Doi, H. Shiono, K. Matsubara, K. Shimizu, Paraquat toxicity is attenuated by 4-phenylbutyrate-induced phosphorylation of ERK2 via PI3K in A549 cells , Biochem. Biophys. Res. Commun. , vol.503 (p.809 - 814) , 2018 , (IF:2.559)
English: M. Asari, H. Matsuura, S. Isozaki, C. Hoshina, K. Okuda, H. Tanaka, K. Horioka, H. Shiono, K. Shimizu, Assessment of DNA degradation of buccal cells under humid conditions and DNA repair by DOP-PCR using locked nucleic acids. , Leg. Med. , vol.35 (p.29 - 33) , 2018 , (IF:1.254)
English: C. Maseda, A. Hayakawa, K. Okuda, M. Asari, H. Tanaka, H. Yamada, S. Jin, K. Horioka, K. Matoba, H. Shiono, K. Matsubara, K. Shimizu, Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Thiosulfate in Human Blood and Urine as an Indicator of Hydrogen Sulfide Poisoning , Leg Med , vol.24 (p.67 - 74) , 2017 , (IF:1.254)
English: Okuda Katsuhiro, Maseda Chikatoshi, Asari Masaru, Isozaki Shotaro, Kiya Hiroshi, Yajima Daisuke, Shiono Hiroshi, Shimizu Keiko, Postmortem diffusion of n-butane and i-butane used for anticontagious plugging spray. , Leg Med , vol.19 (p.83 - 87) , 2016 , (IF:1.254)
English: Asari Masaru, Okuda Katsuhiro, Hoshina Chisato, Omura Tomohiro, Tasaki Yoshikazu, Shiono Hiroshi, Matsubara Kazuo, Shimizu Keiko, Multicolor-based discrimination of 21 short tandem repeats and amelogenin using four fluorescent universal primers. , Anal Biochem , vol.494 (p.16 - 22) , 2016 , (IF:2.275)
English: Yajima Daisuke, Shimizu Keiko, Oka Kumiko, Asari Masaru, Maseda Chikatoshi, Okuda Katsuhiro, Shiono Hiroshi, Ohtani Seiji, Ogawa Katsuhiro, A Case of Sudden Infant Death Due to Incomplete Kawasaki Disease. , J Forensic Sci , vol.61 Suppl 1 (p.S259 - S264) , 2016 , (IF:1.184)
English: S. Jin, H. Hyodoh, K. Matoba, F. Feng, A. Hayakawa, K. Okuda, K. Shimizu, S. Haga, M. Ozaki, K. Terazawa, Development for the measurement of serum thiosulfate using LC–MS/MS in forensic diagnosis of H2S poisoning , Leg Med , vol.22 (p.18 - 22) , 2016 , (IF:1.254)
English: H. Fukuda, K. Nishikawa, Y. Fukunaga, K. Okuda, K. Kodama, K. Matsumoto, A. Kano, M. Shindo, Synthesis of fluorescent molecular probes based on cis-cinnamic acid and molecular imaging of lettuce roots , Tetrahedron , vol.72 (p.6492 - 6498) , 2016 , (IF:2.651)
English: K. Shimizu, T. Ohmura, K. Okuda, M. Asari, H. Shiono, K. Matsubara, Triazolam impairs avoidance reaction-A scientific proof why the victim does not escape from drug-facilitated sexual assaults , Journal of Forensic Psychology , vol.21 , 2016
English: Yajima Daisuke, Asari Masaru, Okuda Katsuhiro, Maseda Chikatoshi, Yamada Hiromi, Ichimaru Chisato, Matsubara Kazuo, Shiono Hiroshi, Iwase Hirotaro, Makino Yosuke, Shimizu Keiko, An objective approach using three indexes for determining fatal hypothermia due to cold exposure; statistical analysis of oxyhemoglobin saturation data. , Leg Med , vol.17 (6) (p.451 - 458) , 2015 , (IF:1.442)
English: Yamamoto Atsushi, Hasui Keisuke, Matsuo Hiroshi, Okuda Katsuhiro, Abe Masato, Matsumoto Kenji, Harada Kazuki, Yoshimura Yuya, Yamamoto Takenori, Ohkura Kazuto, Shindo Mitsuru, Shinohara Yasuo, Bongkrekic acid analogue, lacking one of the carboxylic groups of its parent compound, shows moderate but pH-insensitive inhibitory effects on the mitochondrial ADP/ATP carrier. , Chem Biol Drug Des , vol.86 (5) (p.1304 - 1322) , 2015 , (IF:2.802)
English: Matsumoto Kenji, Suyama Masaki, Fujita Satoshi, Moriwaki Takuya, Sato Yukiko, Aso Yoshifumi, Muroshita Satoshi, Matsuo Hiroshi, Monda Keishi, Okuda Katsuhiro, Abe Masato, Fukunaga Hiroyuki, Kano Arihiro, Shindo Mitsuru, Efficient Total Synthesis of Bongkrekic Acid and Apoptosis Inhibitory Activity of Its Analogues. , Chemistry , vol.21 (32) (p.11590 - 11602) , 2015 , (IF:5.771)
English: Asari, M. and Okuda, K. and Yajima, D. and Maseda, C. and Hoshina, C. and Omura, T. and Shiono, H. and Matsubara, K. and Shimizu, K, Rapid genotyping of 25 autosomal STRs in a Japanese population using fluorescent universal primers containing locked nucleic acids , J. Forensic Leg. Med. , vol.31 (p.36 - 41) , 2015 , (IF:0.87)
English: Sugiyama, C. and Kotake, Y. and Yamaguchi, M. and Umeda, K. and Tsuyama, Y. and Sanoh, S. and Okuda, K. and Ohta, S, Development of a simple measurement method for GluR2 protein expression as an index of neuronal vulnerability , Toxicology Reports , vol.2 (p.450 - 460) , 2015
English: Cipelli, R and Harries, L. and Okuda, K. and Yoshihara, S. and Melzer, D. and Galloway, T. , Bisphenol A modulates the metabolic regulator oestrogen-related receptor-α in T-cells , Reproduction , vol.147 (4) (p.419 - 426) , 2014 , (IF:3.174)
English: Wasano, N. and Sugano, M. and Nishikawa, K. and Okuda, K. and Shindo, M. and Park, SY. and Hiradate, S. and Kamo, T. and Fujii, Y., Transcriptomic evaluation of the enhanced plant growth-inhibitory activity caused by derivatization of cis-cinnamic acid , Journal of Pesticide Science , vol.39 (2) (p.85 - 90) , 2014 , (IF:0.722)
English: Okuda, K. and Nishikawa, K. and Fukuda, H. and Fujii, Y. and Shindo, M., cis-Cinnamic Acid Selective Suppressors Distinct from Auxin Inhibitors , Chemical & Pharmaceutical Bulletin , vol.62 (p.600 - 607) , 2014 , (IF:1.164)
English: Kotake, Y. and Sekiya, Y. and Okuda, K. and Ohta, S, Detection of a novel neurotoxic metabolite of Parkinson’s disease-related neurotoxin, 1-benzyl-1,2,3,4-tetrahydroisoquinoline , The Journal of Toxicological Sciences , vol.39 (p.749 - 754) , 2014 , (IF:1.292)
English: Contu, V.R. and Kotake, Y. and Toyama, T. amd Okuda, K. and Miyara, M. and Sakamoto, S. and Samizo, S. and Sanoh, S. and Kumagai, Y. and Ohta, S, Endogenous Neurotoxic Dopamine Derivative Covalently Binds to Parkinson’s Disease-Associated Ubiquitin C-Terminal Hydrolase L1 (UCH-L1) and Alters Its Structure and Function , Journal of Neurochemistry , vol.130 (p.826 - 838) , 2014 , (IF:4.281)
English: Yamada, Y and Nakamura, K. and Furukawa, R. and Kawamura, E. and Moriwaki, T. and Matsumoto, K. and Okuda, K. and Shindo, M. and Harashima, H., Mitochondrial delivery of bongkrekic acid using a MITO-porter prevents the induction of apoptosis in human hela cells , J. Pharm. Sci. , vol.102 (3) (p.1008 - 1015) , 2013 , (IF:3.007)
English: Wasano, N and Sugano, M. and Nishikawa, K. and Okuda, K. and Shindo, M. and Abe, H. and Park, S.-Y. and Hiradate, S. and Kamo, T. and Fujii, Y., Root-specific induction of early auxin-responsive genes in Arabidopsis thaliana by cis-cinnamic acid , Plant Biotechnol. , vol.30 (5) (p.465 - 471) , 2013 , (IF:1.056)
English: Nishikawa, K and Fukuda, H. and Abe, M. and Nakanishi, K. and Tazawa, Y. and Yamaguchi, C. and Hiradate, S. and Fujii, Y. and Okuda, K. and Shindo, M., Design and synthesis of conformationally constrained analogues of cis-cinnamic acid and evaluation of their plant growth inhibitory activity , Phytochemistry , vol.96 (p.223 - 234) , 2013 , (IF:3.35)
English: Isomura, M. and Kotake, Y. and Masuda, K. and Miyara, M. and Okuda, K. and Samizo, S. and Sanoh, S. and Hosoi, T. and Ozawa, K. and Ohta, S., Tributyltin-induced endoplasmic reticulum stress and its Ca2+-mediated mechanism , Toxicol. Appl. Pharmacol. , vol.272 (1) (p.137 - 146) , 2013 , (IF:3.630)
English: Nishikawa, K and Fukuda, H. and Abe, M. and Nakanishi, K. and Taniguchi, T. and Nomura, T. and Yamaguchi, C. and Hiradate, S. and Fujii, Y. and Okuda, K. and Shindo, M., Substituent effects of cis-cinnamic acid analogues as plant growh inhibitors , Phytochemistry , vol.96 (p.132 - 147) , 2013 , (IF:3.35)
English: Okuda, K and Hasui, K. and Abe, M. and Matsumoto, K. and Shindo, M., Molecular design, synthesis, and evaluation of novel potent apoptosis inhibitors inspired from bongkrekic acid , Chem. Res. Toxicol. , vol.25 (10) (p.2253 - 2260) , 2012
English: Abe, M and Nishikawa, K. and Fukuda, H. and Nakanishi, K. and Tazawa, Y. and Taniguchi, T. and Park, S.-Y. and Hiradate, S. and Fujii, Y. and Okuda, K. and Shindo, M., Key structural features of cis-cinnamic acid as an allelochemical , Phytochemistry , vol.84 (p.56 - 67) , 2012
English: Okuda, K. and Fukuuchi, T. and Takiguchi, M. and Yoshihara, S., Novel pathway of metabolic activation of bisphenol a-related compounds for estrogenic activity , Drug Metab. Dispos. , vol.39 (9) (p.1696 - 1703) , 2011
English: Okuda, K. and Takiguchi, M. and Yoshihara, S., In vivo estrogenic potential of 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene, an active metabolite of bisphenol A, in uterus of ovariectomized rat , Toxicol. Lett. , vol.197 (1) (p.7 - 11) , 2010
English: Fukuuchi, T. and Okuda, K. and Yoshihara, S. and Ohta, S, A candidate anti-prion disease agent, 2,2́-biquinoline, decreases expression of prion protein and mRNA in prion-infected cells , J. Health Sci. , vol.55 (4) (p.586 - 592) , 2009
English: Kotake, Y. and Sekiya, Y. and Okuda, K. and Ohta, S., Cytotoxicity of 17 tetrahydroisoquinoline derivatives in SH-SY5Y human neuroblastoma cells is related to mitochondrial NADH-ubiquinone oxidoreductase inhibition , NeuroToxicology , vol.28 (1) (p.27 - 32) , 2007
English: Okuda, K. and Kotake, Y and Ohta, S., Parkinsonism-preventing activity of 1-methyl-1,2,3,4-tetrahydroisoquinoline derivatives in C57BL mouse in vivo , Biol. Pharm. Bull. , vol.29 (7) (p.1401 - 1403) , 2006
English: Kotake, Y. and Taguchi, R. and Okuda, K. and Sekiya, Y. and Tasaki, Y. and Hirobe, M. and Ohta, S., Neuroprotective effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline on cultured rat mesencephalic neurons in the presence or absence of various neurotoxins , Brain Res. , vol.1033 (2) (p.143 - 150) , 2005
English: Kotake, Y. and Okuda, K. and Kamizono, M. and Matsumoto, N. and Tanahashi, T. and Hara, H. and Caparros-Lefebvre, D. and Ohta, S., Detection and determination of reticuline and N-methylcoculaurine in the Annonaceae family using liquid chromatography-tandem mass spectrometry , J. Chromatogr. B Anal. Technol. Biomed. Life Sci. , vol.806 (1) (p.75 - 78) , 2004
English: Okuda, K. and Kotake, Y. and Ohta, S., Neuroprotective or neurotoxic activity of 1-methyl-1,2,3,4- tetrahydroisoquinoline and related compounds , Bioorg. Med. Chem. Lett. , vol.13 (17) (p.2853 - 2855) , 2003
English: Okuda, K. and Kotake, Y. and Ohta, S., Determination method of 1-methyl-1,2,3,4-tetrahydroisoquinoline, an endogenous parkinsonism-preventing substance, by radioimmunoassay , Life Sci. , vol.70 (24) (p.2871 - 2883) , 2002
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