1 - 17 of about 17
English: Yasushi Ito, Dimitry Ofengeim, Ayaz Najafov, Sudeshna Das, Shahram Saberi, Ying Li, Junichi Hitomi, Hong Zhu, Hongbo Chen, Lior Mayo, Jiefei Geng, Palak Amin, Judy Park DeWitt, Adnan Kasim Mookhtiar, Marcus Florez, Amanda Tomie Ouchida, Jian-bing Fan, Manolis Pasparakis, Michelle A Kelliher, John Ravits, Junying Yuan, RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS , Science , 2016
English: D E Christofferson , Y Li , J Hitomi , W Zhou , C Upperman , H Zhu , S A Gerber , S Gygi , J Yuan, A novel role for RIP1 kinase in mediating TNFα production , Cell Death & Disease , 2012
English: Junichi Hitomi , Dana E. Christofferson , Aylwin Ng , Jianhua Yao , Alexei Degterev , Ramnik J. Xavier , Junying Yuan, Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway , Cell , 2008
English: Alexei Degterev , Junichi Hitomi , Megan Germscheid , Irene L Ch'en , Olga Korkina , Xin Teng , Derek Abbott , Gregory D Cuny , Chengye Yuan , Gerhard Wagner , Stephen M Hedrick , Scott A Gerber , Alexey Lugovskoy , Junying Yuan, Identification of RIP1 kinase as a specific cellular target of necrostatins , Nat.Chem.Biol. , 2008
English: Futoshi Yukioka , Shinsuke Matsuzaki , Keisuke Kawamoto , Yoshihisa Koyama , Junichi Hitomi , Taiichi Katayama , Masaya Tohyama, Presenilin-1 mutation activates the signaling pathway of caspase-4 in endoplasmic reticulum stress-induced apoptosis , Neurochemistry International , 2008
English: Satoru Yamagishi , Yoshihisa Koyama , Taiichi Katayama , Manabu Taniguchi , Junichi Hitomi , Masaaki Kato , Masashi Aoki , Yasuto Itoyama , Shinsuke Kato , Masaya Tohyama, An In Vitro Model for Lewy Body-Like Hyaline Inclusion/Astrocytic Hyaline Inclusion: Induction by ER Stress with an ALS-Linked SOD1 Mutation , PLoS ONE , 2007
English: Kayoko Oono, Takunari Yoneda, Takayuki Manabe, Satoru Yamagishi, Satoshi Matsuda, Junichi Hitomi, Shingo Miyata, Tatsuyoshi Mizuno, Kazunori Imaizumi, Taiichi Katayama, Masaya Tohyama, JAB1 participates in unfolded protein responses by association and dissociation with IRE1 , Neurochemistry International , 2004
English: Junichi Hitomi , Taiichi Katayama , Yutaka Eguchi , Takashi Kudo , Manabu Taniguchi , Yoshihisa Koyama , Takayuki Manabe , Satoru Yamagishi , Yoshio Bando , Kazunori Imaizumi , Yoshihide Tsujimoto , Masaya Tohyama, Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Aβ-induced cell death , J. Cell Biol. , 2004
English: Junichi Hitomi , Taiichi Katayama , Manabu Taniguchi , Akiko Honda , Kazunori Imaizumi , Masaya Tohyama, Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12 , Neuroscience Letters , 2004
English: Taiichi Katayama , Kazunori Imaizumi , Takunari Yoneda , Manabu Taniguchi , Akiko Honda , Takayuki Manabe , Junichi Hitomi , Kayoko Oono , Kousuke Baba , Shingo Miyata , Shinsuke Matsuzaki , Koichi Takatsuji , Masaya Tohyama, Role of ARF4L in Recycling Between Endosomes and the Plasma Membrane , Cellular and Molecular Neurobiology , 2004
English: T Manabe , T Katayama , N Sato , F Gomi , J Hitomi , T Yanagita , T Kudo , A Honda , Y Mori , S Matsuzaki , K Imaizumi , A Mayeda , M Tohyama, Induced HMGA1a expression causes aberrant splicing of Presenilin-2 pre-mRNA in sporadic Alzheimer's disease , Cell Death & Differentiation , 2003
English: Naoya Sato , Kazunori Imaizumi , Takayuki Manabe , Manabu Taniguchi , Junichi Hitomi , Taiichi Katayama , Takunari Yoneda , Takashi Morihara , Yuichi Yasuda , Tsutomu Takagi , Takashi Kudo , Takehide Tsuda , Yasuto Itoyama , Takao Makifuchi , Paul E. Fraser , Peter St George-Hyslop , Masaya Tohyama, Increased Production of β-Amyloid and Vulnerability to Endoplasmic Reticulum Stress by an Aberrant Spliced Form of Presenilin 2 , Journal of Biological Chemistry , 2001
English: Takashi Morihara , Taiichi Katayama , Naoya Sato , Takunari Yoneda , Takayuki Manabe , Junichi Hitomi , Hirohito Abe , Kazunori Imaizumi , Masaya Tohyama, Absence of endoproteolysis but no effects on amyloid β production by alternative splicing forms of presenilin-1, which lack exon 8 and replace D257A , Molecular Brain Research , 2000
English: Ko Miyoshi , Taiichi Katayama , Kazunori Imaizumi , Manabu Taniguchi , Yasutake Mori , Junichi Hitomi , Daishi Yui , Takayuki Manabe , Fumi Gomi , Takunari Yoneda , Masaya Tohyama, Characterization of mouse Ire1α: cloning, mRNA localization in the brain and functional analysis in a neural cell line , Molecular Brain Research , 2000
English: Fumi Gomi , Kazunori Imaizumi , Takunari Yoneda , Manabu Taniguchi , Yasutake Mori , Ko Miyoshi , Junichi Hitomi , Takashi Fujikado , Yasuo Tano , Masaya Tohyama, Molecular Cloning of a Novel Membrane Glycoprotein, Pal, Specifically Expressed in Photoreceptor Cells of the Retina and Containing Leucine-Rich Repeat , The Journal of Neuroscience , 2000
English: Takunari Yoneda , Kazunori Imaizumi , Mitsuyo Maeda , Daishi Yui , Takayuki Manabe , Taiichi Katayama , Naoya Sato , Fumi Gomi , Takashi Morihara , Yasutake Mori , Ko Miyoshi , Junniti Hitomi , Shinya Ugawa , Shuichi Yamada , Masaru Okabe , Masaya Tohyama, Regulatory Mechanisms of TRAF2-mediated Signal Transduction by Bcl10, a MALT Lymphoma-associated Protein , Journal of Biological Chemistry , 2000
English: Taiichi Katayama , Kazunori Imaizumi , Naoya Sato , Ko Miyoshi , Takashi Kudo , Junichi Hitomi , Takashi Morihara , Takunari Yoneda , Fumi Gomi , Yasutake Mori , Yuka Nakano , Junji Takeda , Takehide Tsuda , Yasuto Itoyama , Ohoshi Murayama , Akihiko Takashima , Peter St George-Hyslop , Masatoshi Takeda , Masaya Tohyama, Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response , Nature Cell Biology , 1999
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