Updated on 2024/12/12

写真a

 
TERAZAWA Takeshi
 
Organization
Center Advanced Medical Engineering Research Center
Contact information
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Degree

  • Ph.D(Engineering) ( 2019.3   Hokkaido University )

  • Master (Engineering) ( 2005.3   Tohoku University )

Research Interests

  • Machine Learning

  • Biomaterial

  • Tissue engineering

  • Biomedical engineering

Research Areas

  • Life Science / Biomaterials

  • Life Science / Biomedical engineering

  • Others / Others  / 生体医工学

Education

  • Hokkaido University   Graduate School of Chemical Sciences and Engineering   Division of Chemical Sciences and Engineering

    2016.4 - 2019.3

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    Country: Japan

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  • Tohoku University   Graduate School of Engineering   Department of Electrical and Communication Engineering

    2003.4 - 2005.3

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    Country: Japan

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  • Iwate University   Faculty of Engineering   Department of Electrical and Electronic Engineering

    1999.4 - 2003.3

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    Country: Japan

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Research History

  • Asahikawa Medical University   Advanced Medical Engineering Research Center   Associate professor / Lecturer

    2020.10

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    Country:Japan

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  • AICHI UNIVERSITY OF TECHNOLOGY   Faculty of Engineering Faculty of Engineering   Associate Professor

    2020.4 - 2020.9

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    Country:Japan

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  • AICHI UNIVERSITY OF TECHNOLOGY   Faculty of Engineering Faculty of Engineering   Assistant Professor

    2019.4 - 2020.3

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  • National Cerebral and Cardiovascular Center   Department of Artificial Organs   Researcher

    2017.6 - 2018.8

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  • Fuji Heavy Industries Ltd.(Subaru Corporation)

    2008.6 - 2016.3

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  • Fuji Heavy Industries Ltd.(Subaru Corporation)   Subaru Technical Research Center

    2005.4 - 2008.6

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Professional Memberships

  • SOCIETY OF AUTOMOTIVE ENGINEERS OF JAPAN

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  • The Asia-Pacific Society for Artificial Organs (APSAO)

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  • THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE

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  • JAPANESE SOCIETY FOR ARTIFICIAL ORGANS

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Committee Memberships

  • 日本人工臓器学会   評議員  

    2021.5   

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    Committee type:Academic society

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  • 自動車技術会   ISO/TC204走行制御分科会WG14(LKAS/RBDPS)  

    2008.10 - 2016.2   

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    Committee type:Academic society

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Papers

  • Introduction of "Toy-Creation Contest" in CAD/CAM/CAE Education and Verification of Educational Effectiveness Using Bayesian Networks Reviewed

    Takeshi Terazawa, Atsushi Kondo, Toshiya Arakawa

    International Journal of Innovative Computing, Information and Control   19 ( 5 )   1439 - 1454   2023.10

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    File: ijicic-190507.pdf

    DOI: 10.24507/ijicic.19.05.1439

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  • Pre-implantation evaluation of a small-diameter, long vascular graft (Biotube®) for below-knee bypass surgery in goats. Reviewed International journal

    Yasuhide Nakayama, Ryosuke Iwai, Takeshi Terazawa, Tsutomu Tajikawa, Tadashi Umeno, Takayuki Kawashima, Yumiko Nakashima, Yasuyuki Shiraishi, Akihiro Yamada, Ryuji Higashita, Manami Miyazaki, Tomonori Oie, Satoki Kadota, Nozomi Yabuuchi, Fumie Abe, Marina Funayama-Iwai, Tomoyuki Yambe, Shinji Miyamoto

    Journal of biomedical materials research. Part B, Applied biomaterials   110 ( 11 )   2387 - 2398   2022.5

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    There are no small-diameter, long artificial vascular grafts for below-knee bypass surgery in chronic limb-threatening ischemia. We have developed tissue-engineered vascular grafts called "Biotubes®" using a completely autologous approach called in-body tissue architecture (iBTA). This study aimed at pre-implantation evaluation of Biotube and its in vivo preparation device, Biotube Maker, for use in below-knee bypass surgery. Forty nine makers were subcutaneously embedded into 17 goats for predetermined periods (1, 2, or 3 months). All makers produced Biotubes as designed without inflammation over all periods, with the exception of a few cases with minor defects (success rate: 94%). Small hole formation occurred in only a few cases. All Biotubes obtained had an inner diameter of 4 mm and a length of 51 to 52 cm with a wall thickness of 594 ± 97 μm. All Biotubes did not kink when completely bent under an internal pressure of 100 mmHg and did not leak without any deformation under a water pressure of 200 mmHg. Their burst strength was 2409 ± 473 mmHg, and suture retention strength was 1.75 ± 0.27 N, regardless of the embedding period, whereas tensile strength increased from 7.5 ± 1.3 N at 1 month to 9.7 ± 2.0 N at 3 months with the embedding period. The amount of water leakage from the needle holes prepared in the Biotube wall was approximately 1/7th of that in expanded polytetrafluoroethylene vascular grafts. The Biotubes could be easily connected to each other without cutting or anastomosis leaks. They could be stored for at least 1 year at room temperature. This study confirmed that even Biotubes formed 1 month after embedding of Biotube Makers had properties comparable to arteries.

    DOI: 10.1002/jbm.b.35084

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  • Verification of Synergistic Effects of Education on Mechanism Theory and CAE for Mechanism Analysis Reviewed

    Takeshi TERAZAWA, Toshiya ARAKAWA

    Journal of the Japan Society for Precision Engineering   88 ( 2 )   174 - 180   2022.2

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Japan Society for Precision Engineering  

    File: 88_174.pdf

    DOI: 10.2493/jjspe.88.174

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  • Acute Phase Pilot Evaluation of Small Diameter Long iBTA-Induced Vascular Graft “Biotube” in a Goat Model Reviewed International journal

    Ryuji Higashita, Yasuhide Nakayama, Yasuyuki Shiraishi, Ryosuke Iwai, Yusuke Inoue, Akihiro Yamada, Takeshi Terazawa, Tsutomu Tajikawa, Manami Miyazaki, Mamiko Ohara, Tadashi Umeno, Keitaro Okamoto, Tomonori Oie, Tomoyuki Yambe, Shinji Miyamoto

    EJVES Vascular Forum   54   27 - 35   2022.1

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    Objective: There is a need for small diameter vascular substitutes in the absence of available autologous material. A small diameter, long tissue engineered vascular graft was developed using a completely autologous approach called "in body tissue architecture technology (iBTA)". The aim of this pilot study was to evaluate "Biotubes", iBTA induced autologous collagenous tubes, for their potential use as small diameter vascular bypass conduits. Methods: Biotubes (internal diameter 4 mm, length 50 cm, wall thickness 0.85 mm) were prepared by subcutaneous embedding of plastic moulds (Biotube Maker) in three goats for approximately two months. Allogenic Biotubes (length 10 cm [n = 2], 15 cm [n = 2], 22 cm [n = 2]) were bypassed to both carotid arteries by end to side anastomosis with their ligation between the anastomoses in another three goats. Residual Biotubes were examined for their mechanical properties. After four weeks, the harvested Biotubes were evaluated histologically. Results: All Biotubes had sufficient pressure resistance, approximately 3000 mmHg. Although wall thickening occurred at two proximal anastomosis sites, all six grafts were patent without luminal thrombus formation, stenosis, or aneurysm deformation throughout the implantation period. Endothelial cells covered both anastomosis sites almost completely, with partial covering in the central portion of the grafts. Furthermore, α smooth muscle actin positive cells infiltrated the middle layer along almost the entire graft length. Conclusion: This preliminary study showed that small diameter, long, tissue engineered Biotubes could function properly as arterial bypass conduits in a large animal for one month without any abnormal change in vascular shape. Thus, small diameter, long Biotubes are potentially viable conduits, which are biocompatible and labour non-intensive, and therefore, suitable for clinical practice. Additionally, Biotubes can start the regeneration process in a short period of time.

    DOI: 10.1016/j.ejvsvf.2022.01.004

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  • iBTA-Induced Biotube<sup>®</sup> Blood Vessels: 2020 Update Reviewed

    Yasuhide Nakayama, Ryuji Higashita, Yasuyuki Shiraishi, Tadashi Umeno, Tsutomu Tajikawa, Akihiro Yamada, Kazuki Mori, Manami Miyazaki, Mamiko Ohara, Ryosuke Iwai, Takeshi Terazawa, Tomonori Oie, Tomoyuki Yambe, Shinji Miyamoto

    Kidney and Dialysis   1 ( 1 )   3 - 13   2021.6

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    DOI: 10.3390/kidneydial1010002

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  • Aortic valve neocuspidization with in-body tissue-engineered autologous membranes: preliminary results in a long-term goat model. Reviewed International journal

    Takayuki Kawashima, Tadashi Umeno, Takeshi Terazawa, Tomoyuki Wada, Takashi Shuto, Haruto Nishida, Hirofumi Anai, Yasuhide Nakayama, Shinji Miyamoto

    Interactive cardiovascular and thoracic surgery   32 ( 6 )   969 - 977   2021.5

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    OBJECTIVES: Aortic valve neocuspidization has shown satisfactory clinical outcomes; however, autologous pericardium durability is a concern for young patients. This study applied an autologous collagenous membrane (Biosheet®), produced by in-body tissue architecture, to aortic valve neocuspidization and investigated its long-term outcome in a goat model. METHODS: Moulds were embedded subcutaneously in 6 goats. After 2 months, Biosheets formed in the moulds. We performed aortic valve neocuspidization using a portion of the sheets with a thickness of 0.20-0.35 mm, measured by optical coherence tomography. Animals were subjected to echocardiography and histological evaluation at 6 months (n = 3) and 12 months (n = 3). As a control, the glutaraldehyde-treated autologous pericardium was used in 4 goats that were similarly evaluated at 12 months. RESULTS: All animals survived the scheduled period. At 6 months, Biosheets maintained valve function and showed a regeneration response: fusion to the annulus, cell infiltration to the leaflets and appearance of elastic fibres at the ventricular side. After 12 months, the regenerative structure had changed little without regression, and there was negligible calcification in the 1/9 leaflets. However, all cases had one leaflet tear, resulting in moderate-to-severe aortic regurgitation. In the pericardium group, three-fourths of the animals experienced moderate-to-severe aortic regurgitation with a high rate of calcification (9/12 leaflets). CONCLUSIONS: Biosheets may have regeneration potential and anti-calcification properties in contrast to autologous pericardium. However, in order to obtain reliable outcome, further improvements are required to strictly control and optimize its thickness, density and homogeneity.

    DOI: 10.1093/icvts/ivab015

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  • Mechanical characterization of an in-body tissue-engineered autologous collagenous sheet for application as an aortic valve reconstruction material Reviewed International journal

    Takeshi Terazawa, Takayuki Kawashima, Tadashi Umeno, Tomoyuki Wada, Shigeyuki Ozaki, Shinji Miyamoto, Yasuhide Nakayama

    Journal of Biomechanics   99   109528 - 109528   2020.1

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    © 2019 The reconstruction of the aortic valve using glutaraldehyde-treated autologous pericardium is known as “aortic valve neo-cuspidization” (AVNeo). In-body tissue architecture (iBTA), a cell-free, in vivo tissue-engineering technology that can form autologous implantable tissues of the desired shape by subcutaneous embedding specially designed molds, was used to prepare sheet-like collagenous tissues called “Biosheets”. Cylindrical molds with several line slits arranged in an alternating (n = 30) or parallel (n = 36) pattern were subcutaneously embedded in goats (n = 12) for 2 or 3 months. The tubular tissues formed in the molds were dried and then cut in the longitudinal direction, thus obtaining Biosheets (5 × 7 cm). The success rate was 97.6% when using the alternating-pattern molds and 97.2% for the parallel molds. Thickness mapping of the Biosheets showed that their entire surface, except for the line-projection portions, was smooth without any defects. The average wall thickness could be controlled over a range of ca. 0.2–0.5 mm by changing the size of the gap (0.75–1.5 mm) in the molds. The alternating slit-patterned Biosheets were found to be almost isotropic in their mechanical properties (ultimate tensile strength, fracture strain, and Young's modulus). Although the composition of the Biosheet wall was heterogeneous in terms of its density (which varied with the thickness), the breaking strength of all the alternating-patterned Biosheets increased almost linearly with the thickness within the range of the thickness of clinically used glutaraldehyde-treated pericardium as a control, and was larger than that of human aortic valve leaflets. Therefore, the alternating-patterned Biosheets have potential for use in an alternative aortic leaflet material in AVNeo.

    DOI: 10.1016/j.jbiomech.2019.109528

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  • Initial 3-year results of first human use of an in-body tissue-engineered autologous “Biotube” vascular graft for hemodialysis Reviewed

    Yasuhide Nakayama, Yoshiyuki Kaneko, Noriko Okumura, Takeshi Terazawa

    Journal of Vascular Access   21 ( 1 )   110 - 115   2020.1

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    © The Author(s) 2019. This study presents the initial 3-year results of the first in-human study of internal shunt restoration using completely autologous vascular grafts, “Biotubes,” based on in-body tissue architecture. Biotubes (diameter, 6 mm; length, 7 cm) were prepared as autologous collagenous tubular tissues with approximately 0.5 mm wall thickness by embedding molds (two per patient), assembled with a silicone rod and a stainless steel pipe with many slits, into the patients’ abdominal subcutaneous tissue for 2 months. Two female patients with end-stage renal disease were undergoing hemodialysis with a high probability of failure due to repeated stenosis every few months at the venous outflow regions over 1.5 years. Biotubes formed in both patients and were bypassed over the venous stenosis region of the arteriovenous shunt. After bypass with Biotubes without living cells, palpable thrill and typical turbulent flow pattern were observed by pulsed-wave Doppler. Follow-up angiography showed no signs of dilation or stenosis after implantation, and puncture could be performed easily without graft damage. In both cases, stenosis of Biotubes occurred after 3–4 months. In the first case, percutaneous transluminal angioplasty was not required for over 2 years after implantation even after the development of Biotube stenosis. In the second case, stenosis at the proximal anastomotic site of the Biotube became prominent, and percutaneous transluminal angioplasty was needed 7 months after implantation and then repeated at up to 2 years. This was the first human study successfully supporting the concept of internal shunt restoration for hemodialysis using an autologous Biotube.

    DOI: 10.1177/1129729819852550

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  • Application of Multi-Body Simulation Environment for Mechanism Education Reviewed

    寺澤武, 荒川俊也

    工学教育   68 ( 6 )   83 - 89   2020

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    Education in mechanism theory is essential for helping university students deeply understand machine. However, for students to imagine a mechanical movement through plane and stationary information is difficult. In addition, simulating and checking how mechanical movement changes along with changing the length of links and the number of pairs is also difficult. In this paper, MATLAB<sup>®</sup>/Simulink<sup>®</sup>/Simscape<sup>TM</sup> Multibody<sup>TM</sup> is applied for mechanism education and some mechanism practice. The introduced program&rsquo; s effect is verified with questionnaires and students&rsquo; GPAs. According to analysis of the questionnaires, the proposal method shows the possibility of improving students&rsquo; understanding and motivation. The practice introduced here is effective for students with rather high GPAs, seeming to improve their motivation for study. However, considering the specification like a university specializing in manufacturing, joining this educational program to 3D CAD education may also be useful for students with relatively low GPAs.

    File: 68_6_83.pdf

    DOI: 10.4307/jsee.68.6_83

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  • Long-term outcomes of patch tracheoplasty using collagenous tissue membranes (biosheets) produced by in-body tissue architecture in a beagle model Reviewed

    Satoshi Umeda, Yasuhide Nakayama, Takeshi Terazawa, Ryosuke Iwai, Shohei Hiwatashi, Kengo Nakahata, Yuichi Takama, Hiroomi Okuyama

    Surgery Today   49 ( 11 )   958 - 964   2019.11

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    © 2019, Springer Nature Singapore Pte Ltd. Purpose: Although various artificial tracheas have been developed, none have proven satisfactory for clinical use. In-body tissue architecture (IBTA) has enabled us to produce collagenous tissues with a wide range of shapes and sizes to meet the needs of individual recipients. In the present study, we investigated the long-term outcomes of patch tracheoplasty using an IBTA-induced collagenous tissue membrane (“biosheet”) in a beagle model. Methods: Nine adult female beagles were used. Biosheets were prepared by embedding cylindrical molds assembled with a silicone rod and a slitting pipe into dorsal subcutaneous pouches for 2 months. The sheets were then implanted by patch tracheoplasty. An endoscopic evaluation was performed after 1, 3, or 12 months. The implanted biosheets were harvested for a histological evaluation at the same time points. Results: All animals survived the study. At 1 month after tracheoplasty, the anastomotic parts and internal surface of the biosheets were smooth with ciliated columnar epithelium, which regenerated into the internal surface of the biosheet. The chronological spread of chondrocytes into the biosheet was observed at 3 and 12 months. Conclusions: Biosheets showed excellent performance as a scaffold for trachea regeneration with complete luminal epithelium and partial chondrocytes in a 1-year beagle implantation model of patch tracheoplasty.

    DOI: 10.1007/s00595-019-01818-5

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  • One-year follow-up study of iBTA-induced allogenic biosheet for repair of abdominal wall defects in a beagle model: a pilot study Reviewed

    T. Terazawa, M. Furukoshi, Y. Nakayama

    Hernia   23 ( 1 )   149 - 155   2019.2

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    © 2018, Springer-Verlag France SAS, part of Springer Nature. Purpose: We evaluated the usefulness of biosheet, an in-body tissue-engineered collagenous membrane, as a novel repair material for abdominal wall defects in a beagle model. Methods: Biosheets were prepared by embedding molds into subcutaneous pouches in two beagle dogs for 2 months, with subsequent storage in 70% ethanol. The obtained biosheets (thickness 0.5 mm, size 25 cm 2 ) were implanted to replace same-size defects in the abdominal wall of two beagles in an allogenic manner. Results: The biosheets were not stressed during suturing and did not split; moreover, patch implantation into the defective wound was easy. No complications such as anastomotic leaks or infections occurred during implantation. One year post-implantation, the thickness of the biosheet implantation section increased to approximately 2.5 mm, corresponding to approximately 70% of the native abdominal wall. A section of the abdominal wall muscle elongated from the periphery of the newly formed collagen layer, and the peritoneum was entirely formed on the peritoneal cavity surface, resulting in partial regeneration of the three-layered abdominal wall. The mechanical strength of the newly formed wall was approximately fivefold higher than the native wall. The elasticity of the biosheet in the low-strain region decreased to approximately 10% post-implantation, similar to the native wall. Conclusions: This pilot study demonstrated that biosheet maintained the abdominal wall without any complications for 1 year post-implantation, and partial regeneration was observed. Although this experiment was limited to two cases, the results indicated that biosheet may serve as a reliable abdominal wall restorative material.

    DOI: 10.1007/s10029-018-1866-1

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  • Tracheal Replacement Using an In-Body Tissue-Engineered Collagenous Tube BIOTUBE with a Biodegradable Stent in a Beagle Model: A Preliminary Report on a New Technique Reviewed International journal

    Shohei Hiwatashi, Yasuhide Nakayama, Satoshi Umeda, Yuichi Takama, Takeshi Terazawa, Hiroomi Okuyama

    European Journal of Pediatric Surgery   29 ( 1 )   90 - 96   2019.2

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    © Georg Thieme Verlag KG Stuttgart. Introduction Tracheal reconstruction for long-segment stenosis remains challenging. We investigate the usefulness of BIOTUBE, an in-body tissue-engineered collagenous tube with a biodegradable stent, as a novel tracheal scaffold in a beagle model. Materials and Methods We prepared BIOTUBEs by embedding specially designed molds, including biodegradable stents, into subcutaneous pouches in beagles. After 2 months, the molds were filled with ingrown connective tissues and were harvested to obtain the BIOTUBEs. The BIOTUBEs, cut to 10- or 20-mm lengths, were implanted to replace the same-length defects in the cervical trachea of five beagles. Endoscopic and fluoroscopic evaluations were performed every week until the lumen became stable. The trachea, including the BIOTUBE, was harvested and subjected to histological evaluation between 3 and 7 months after implantation. Results One beagle died 28 days after 20-mm BIOTUBE implantation because of insufficient expansion and retention force of the stent. The remaining four beagles were implanted with a BIOTUBE reinforced by a strong stent, and all survived the observation period. Endoscopy revealed narrowing of the BIOTUBEs in all four beagles, due to an inflammatory reaction, but patency was maintained by steroid application at the implantation site and balloon dilatation against the stenosis. After 2 months, the lumen gradually became wider. Histological analyses showed that the internal surface of the BIOTUBEs was completely covered with tracheal epithelial cells. Conclusion This study demonstrated the usefulness of the BIOTUBE with a biodegradable stent as a novel scaffold for tracheal regeneration.

    DOI: 10.1055/s-0038-1673709

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  • Thickness mapping of human pericardium using optical coherence tomography and its mechanical property Reviewed

    Takeshi Terazawa, Shigeyuki Ozaki, Eisuke Tatsumi, Yasuhide Nakayama

    Therapeutics & Engineering   31 ( 1 )   27 - 34   2019

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  • Development of long in vivo tissue-engineered “Biotube” vascular grafts Reviewed International journal

    Yasuhide Nakayama, Maya Furukoshi, Takeshi Terazawa, Ryosuke Iwai

    Biomaterials   185   232 - 239   2018.12

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    © 2018 In-body tissue architecture (iBTA), a cell-free, in vivo tissue engineering technology that can produce autologous implantable tissues of the desired shape by subcutaneously embedding specially designed molds, was used to develop long tubular collagenous tissues called Biotubes. Spiral molds for long Biotubes were assembled with an outer pipe-shaped spiral shell and an inner spiral mandrel, and embedded into subcutaneous pouches of beagle dogs or goats for 1 or 2 months. Tubular collagenous tissues were formed at the space between the shell and the mandrel of the mold. Depending on the spiral turn number in the mold, Biotubes of 25 cm or 50 cm (internal diameter 4 mm or 5 mm) were prepared with nearly homogeneous mechanical and histological properties over their entire length. Biotubes stored in 70% ethanol were allogenically implanted into beagle dogs or goats to evaluate their in vivo performance. The 25-cm Biotubes functioned as arterial grafts with no need for luminal modification or mechanical support, and demonstrated vascular reconstruction within 3 months after implantation into dogs. The 50-cm Biotubes functioned as arteriovenous shunt grafts in the neck region of goats without thrombus formation and vascular deformation for 1 month. Thus, the world's longest tissue-engineered vascular grafts with small diameter could be developed using iBTA.

    DOI: 10.1016/j.biomaterials.2018.09.032

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  • Comparison of ethanol concentration as stock solution on mechanical properties of iBTA-induced collagenous tubular tissue “biotube” Reviewed

    Takeshi Terazawa, Yi Ping Lai, Yasuhide Nakayama

    Journal of Biorheology   32 ( 2 )   65 - 70   2018.10

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    © 2018, Japanese Society of Biorheology. All rights reserved. Collagenous tubular tissues “Biotubes,” formed by in-body tissue engineering, is implanted already as clinical vascular grafts in hemodialysis surgery. In almost all previous study, Biotubes were stored in 70% alcohol before implantation, but the influence of alcohol concentration on the mechanical properties of Biotubes has not been investigated in depth. In this study, the mechanical properties of Biotubes stored at room temperature in two different concentrations of ethanol (10% or 70%) were compared through fatigue and tensile tests. Biotubes with an internal diameter of 6 mm and wall thickness of ca. 2 mm was prepared by subcutaneous embedding of molds into goat for two months, and stored in 10% or 70% alcohol solution for 20 d. In the fatigue test, performed by repeatable loading of tension corresponding to arterial pressure (700,000 cycles at 10 Hz), Biotubes stored in 10% solution elongated by approximately 80%, but in 70% solution, the elongation was <20%. Storing Biotubes in high concentration ethanol solution improved practical compliance and prevented stretching. The preservation of ECM with 70% ethanol is a cost effective, safe and easy method.

    File: J_Biorheol_32_65-70_2018.pdf

    DOI: 10.17106/jbr.32.65

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  • Wall thickness control in biotubes prepared using type-C mold Reviewed

    Takeshi Terazawa, Takanori Nishimura, Tomohiro Mitani, Osamu Ichii, Teppei Ikeda, Keigo Kosenda, Eisuke Tatsumi, Yasuhide Nakayama

    Journal of Artificial Organs   21 ( 3 )   387 - 391   2018.9

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    © 2018, The Japanese Society for Artificial Organs. A type-C mold based on in-body tissue architecture was previously developed for preparing small-diameter biotube vascular grafts with a 2-mm diameter and approximately 1-mm wall thickness. In this study, the type-C mold was modified for preparing large-diameter biotubes with controlled wall thicknesses. Four types of molds were assembled by inserting silicone center rods (outer diameters 11, 13, 15, 17 mm) into stainless steel cages (inner diameter 19 mm) and surgically embedded in the abdominal subcutaneous pouches of Holstein cows. After 8–12 weeks, connective tissues occupied the rod–cage gap in the molds to form biotubes. The wall thickness of the biotubes obtained after removing the molds was approximately 1–3 mm, which corresponded to approximately 80% of each gap distance. The breaking strength almost linearly increased with the wall thickness of the biotubes. The strength of the biotubes with wall thickness over 1.5 mm was higher than that of beagle blood vessels. The thickest biotubes were as strong as bovine pericardium and can be used as an alternative trachea graft because of their adequate lumen-holding force.

    DOI: 10.1007/s10047-018-1035-4

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  • Patch esophagoplasty using an in-body-tissue-engineered collagenous connective tissue membrane. Reviewed International journal

    Hiroomi Okuyama, Satoshi Umeda, Yuichi Takama, Takeshi Terasawa, Yasuhide Nakayama

    Journal of pediatric surgery   53 ( 2 )   223 - 226   2018.2

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    AIM: Although many approaches to esophageal replacement have been investigated, these efforts have thus far only met limited success. In-body-tissue-engineered connective tissue tubes have been reported to be effective as vascular replacement grafts. The aim of this study was to investigate the usefulness of an In-body-tissue-engineered collagenous connective tissue membrane, "Biosheet", as a novel esophageal scaffold in a beagle model. METHODS: We prepared Biosheets by embedding specially designed molds into subcutaneous pouches in beagles. After 1-2months, the molds, which were filled with ingrown connective tissues, were harvested. Rectangular-shaped Biosheets (10×20mm) were then implanted to replace defects of the same size that had been created in the cervical esophagus of the beagle. An endoscopic evaluation was performed at 4 and 12weeks after implantation. The esophagus was harvested and subjected to a histological evaluation at 4 (n=2) and 12weeks (n=2) after implantation. The animal study protocols were approved by the National Cerebral and Cardiovascular Centre Research Institute Committee (No. 16048). RESULTS: The Biosheets showed sufficient strength and flexibility to replace the esophagus defect. All animals survived with full oral feeding during the study period. No anastomotic leakage was observed. An endoscopic study at 4 and 12weeks after implantation revealed that the anastomotic sites and the internal surface of the Biosheets were smooth, without stenosis. A histological analysis at 4weeks after implantation demonstrated that stratified squamous epithelium was regenerated on the internal surface of the Biosheets. A histological analysis at 12weeks after implantation showed the regeneration of muscle tissue in the implanted Biosheets. CONCLUSION: The long-term results of patch esophagoplasty using Biosheets showed regeneration of stratified squamous epithelium and muscular tissues in the implanted sheets. These results suggest that Biosheets may be useful as a novel esophageal scaffold.

    DOI: 10.1016/j.jpedsurg.2017.11.004

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  • Development of Active Lane Keeping and Backward Throttle Management

    水谷公一, 小山哉, 寺澤武, 田村悠一郎, 中島博人, 白石英一, 江副志郎

    スバル技報   ( 41 )   89 - 96   2014

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  • Development of Active Lane Keeping System with Stereo Camera Recognition by Color Images Reviewed

    小山哉, 寺澤武, 田村悠一郎, 白石英一, 江副志郎, 水谷公一

    自動車技術   68 ( 12 )   48 - 54   2014

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  • Lane Keeping Assistance System which Considers Driver’s Feed-forward Steering Characteristics

    寺澤武, 工藤新也, 小山哉, 狩谷悠史, 藤岡健彦

    スバル技報   ( 35 )   158 - 163   2008

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  • カテーテル治療へ応用可能な自己組織生体弁(バイオバルブ)の開発

    永吉 智紀, 井上 雄介, 寺澤 武, 佐藤 康史, 武輪 能明

    北海道外科雑誌   69 ( 1 )   72 - 73   2024.6

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    File: VOL69No1.pdf

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  • Investigation of the possibility of substituting an autologous biological heart valve for various valve diseases

    Takewa Y., Inoue Y., Terazawa T., Sato Y.

    ESAO Abstract Book   46 ( 7 )   409 - 410   2023.7

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    DOI: 10.1177/03913988231184027

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  • Development of an aggressive therapy to administer drugs directly into the trachea to improve survival and achieve early weaning of patients on ECMO

    Inoue Y, Sato Y, Terazawa T, Yamada A, Takewa Y

    ESAO Abstract Book   46 ( 7 )   434 - 434   2023.7

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    DOI: 10.1177/03913988231184027

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  • 敵対的生成ネットワークによる人工病理画像が深層学習の組織検出精度に与える影響

    一宮 光悦, 寺澤 武, 荒川 俊也

    日本病理学会会誌   112 ( 1 )   384 - 384   2023.3

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  • ステンレス製皮下植え込みデバイスが生体の組織形成に与える影響

    佐藤康史, 寺澤武, 井上雄介, 武輪能明

    人工臓器(日本人工臓器学会)   52 ( 2 )   S - 117   2023

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  • 圧電性ポリ乳酸材料の荷電性が生体内形成組織の物性に与える影響

    寺澤武, 佐藤康史, 井上雄介, 中西修一, 辻雅之, 山崎洸生, 白木秀幸, 武輪能明

    人工臓器(日本人工臓器学会)   52 ( 2 )   S - 98   2023

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  • ウイルス感染症などに起因する重症肺炎に対するECMO装着下での経気道的治療法の開発

    井上雄介, 佐藤康史, 寺澤武, 武輪能明

    人工臓器(日本人工臓器学会)   52 ( 2 )   S - 56   2023

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  • 様々な大動脈弁疾患に対する自己組織生体弁を代用とする可能性の検討

    武輪能明, 井上雄介, 寺澤武, 佐藤康史

    日本心臓血管外科学会学術総会(Web)   53rd   2023

  • Development of Novel Autologous Tissue Engineered Artificial Heart Valves by in vivo Tissue Engineering Process

    佐藤康史, 寺澤武, 井上雄介, 武輪能明

    日本生物工学会大会講演要旨集   75th   94 - 94   2023

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  • TPVIへの適応を目指した自己拡張ステント一体型自己組織生体弁の開発

    佐藤康史, 寺澤武, 井上雄介, 高松賢介, 太田邦博, 武輪能明

    人工臓器(日本人工臓器学会)   52 ( 2 )   S - 98   2023

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  • 生体内組織形成術を用いたBio-Culture-Plateの開発と性能評価

    佐藤 康史, 寺澤 武, 井上 雄介, 武輪 能明

    北海道外科雑誌   67 ( 1 )   91 - 91   2022.6

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  • 自己組織心臓弁グラフト形成用鋳型の開発と臨床応用の可能性検証

    山名 智尋, 寺澤 武, 堀江 風花, 佐藤 康史, 井上 雄介, 武輪 能明

    北海道外科雑誌   67 ( 1 )   90 - 91   2022.6

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  • COVID-19肺炎重症例に対するECMO下での経気道的治療法確立への挑戦

    堀江 風花, 井上 雄介, 佐藤 康史, 山名 智尋, 寺澤 武, 武輪 能明

    北海道外科雑誌   67 ( 1 )   91 - 91   2022.6

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  • 生体内組織形成術を用いたBio-Culture-Plateの開発と性能評価

    佐藤 康史, 寺澤 武, 井上 雄介, 武輪 能明

    北海道外科雑誌   67 ( 1 )   91 - 91   2022.6

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  • 自己組織心臓弁グラフト形成用鋳型の開発と臨床応用の可能性検証

    山名 智尋, 寺澤 武, 堀江 風花, 佐藤 康史, 井上 雄介, 武輪 能明

    北海道外科雑誌   67 ( 1 )   90 - 91   2022.6

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  • AIを用いた数理最適化演算と流体 構造連成解析による至適心臓弁形状モデリング手法の開発

    寺澤 武

    人工臓器   51 ( 1 )   25 - 26   2022.6

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  • COVID-19肺炎重症例に対するECMO下での経気道的治療法確立への挑戦

    堀江 風花, 井上 雄介, 佐藤 康史, 山名 智尋, 寺澤 武, 武輪 能明

    北海道外科雑誌   67 ( 1 )   91 - 91   2022.6

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  • 圧電性ポリ乳酸繊維を用いた移植用グラフトの開発

    佐藤康史, 寺澤武, 井上雄介, 武輪能明

    人工臓器(日本人工臓器学会)   51 ( 2 )   S - 89   2022

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  • 自己組織生体弁はロス手術よりも進化した大動脈弁置換の選択肢となり得るか?

    武輪能明, 井上雄介, 寺澤武, 佐藤康史

    人工臓器(日本人工臓器学会)   51 ( 2 )   S - 153   2022

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  • 敵対的生成ネットワーク(GAN)によるディープラーニング用人工病理画像生成の可能性

    寺澤武, 一宮光悦, 諏訪陵弥, 荒川俊也, 佐藤康史, 井上雄介, 武輪能明

    人工臓器(日本人工臓器学会)   51 ( 2 )   S - 203   2022

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  • 生体内組織形成術によるCLOSED型心臓弁グラフト形成用鋳型の開発

    寺澤武, 佐藤康史, 井上雄介, 山名智尋, 山名智尋, 堀江風花, 堀江風花, 中山泰秀, 武輪能明

    人工臓器(日本人工臓器学会)   51 ( 2 )   S - 224   2022

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  • Development and evaluation of biological tissue-derived culture plates (Bio-Culture-Plates) using In Body Tissue Architecture technology

    佐藤康史, 寺澤武, 井上雄介, 武輪能明

    組織培養研究(Web)   40 ( 1 )   2022

  • ECMO装着下における重症肺炎に対する経気道的治療法の開発

    井上雄介, 佐藤康史, 寺澤武, 堀江風花, 山名智尋, 武輪能明, 堀江風花, 山名智尋, 武輪能明

    人工臓器(日本人工臓器学会)   51 ( 2 )   S - 155   2022

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  • 旭川医科大学大型慢性動物実験施設における抗血栓ECMOの開発

    井上 雄介, 寺澤 武, 佐藤 康史, 藤原 立樹, 大内 克洋, 土方 亘, 田仲 結衣, 畠中 晃平, 横田 幸恵, 武輪 能明

    人工臓器   50 ( 2 )   S - 117   2021.10

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  • 生物工学×人工知能 Reviewed

    寺澤武

    生物工学会誌   99 ( 7 )   365 - 365   2021.7

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    File: 99_99.7_365.pdf

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  • ディープラーニングを用いた染色画像内の毛細血管定量化手法の開発

    寺澤 武, 佐藤 康史, 井上 雄介, 武輪 能明, 谷川 諒, 荒川 俊也

    北海道外科雑誌   66 ( 1 )   60 - 60   2021.6

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  • 組織形成・再生過程を定量評価するための病理画像解析用人工知能の開発

    寺澤武, 荒川俊也, 佐藤康史, 井上雄介, 武輪能明

    人工臓器(日本人工臓器学会)   50 ( 2 )   S - 168   2021

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  • 圧電性ポリ乳酸繊維を埋め込み材料にした医療機器の開発

    武輪能明, 井上雄介, 寺澤武, 佐藤康史

    人工臓器(日本人工臓器学会)   50 ( 2 )   S - 162   2021

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  • 自己組織心臓弁グラフト(バイオバルブ)の至適心臓弁形状探索のための鋳型設計法開発

    寺澤武, 佐藤康史, 井上雄介, 武輪能明

    人工臓器(日本人工臓器学会)   50 ( 2 )   S - 74   2021

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  • 生体内組織形成術を用いた微細表面構造を有する生体組織培養基板の作製

    佐藤康史, 寺澤武, 井上雄介, 武輪能明

    人工臓器(日本人工臓器学会)   50 ( 2 )   S - 162   2021

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  • 人工臓器と再生医療:再生医療はどこまで進歩したか?人工臓器との融合は果たして可能か? 人工臓器と再生医療の融合により生まれた組織工学人工弁の開発

    武輪 能明, 井上 雄介, 寺澤 武, 佐藤 康史, 中山 泰秀

    人工臓器   49 ( 2 )   S - 61   2020.10

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  • 生体内組織形成術(iBTA)による脱細胞化牛バイオシートを用いた成ヤギ大動脈弁形成術の経験

    梅野 惟史, 岡本 啓太郎, 河島 毅之, 和田 朋之, 穴井 博文, 岩井 良輔, 寺澤 武, 中山 泰秀, 宮本 伸二

    日本胸部外科学会定期学術集会   73回   COO11 - 11   2020.10

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  • 自動運転の過信・依存を抑制する操舵HMIの提案

    壁谷直樹, 寺澤武, 荒川俊也

    計測自動制御学会システム・情報部門学術講演会講演論文集(CD-ROM)   2020   2020

  • 深層学習の医用画像診断への応用

    谷川諒, 寺澤武, 荒川俊也

    計測自動制御学会システム・情報部門学術講演会講演論文集(CD-ROM)   2020   2020

  • 大動脈弁再建術における再生型弁膜材料としてのバイオシートの可能性

    中山 泰秀, 寺澤 武, 河島 毅之, 岡本 啓太郎, 宮本 伸二

    日本小児循環器学会雑誌   35 ( Suppl.1 )   s1 - 226   2019.6

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  • 人工結合組織シート(バイオシート)の作製鋳型による構造変化 細胞導入スリットによる違い

    河島 毅之, 梅野 惟史, 岡本 啓太郎, 和田 朋之, 首藤 敬史, 寺澤 武, 中山 泰秀, 安田 愛子, 川里 浩明, 巽 英介, 島田 達生, 宮本 伸二

    医学生物学電子顕微鏡技術学会誌   32 ( 1 )   35 - 35   2019.3

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  • 生体内組織形成術を用いて作製したウシ由来バイオシートの性状に及ぼす生体内環境の影響

    今山 知佳, 寺澤 武, 中山 泰秀, 三谷 朋弘, 市居 修, 池田 哲平, 小千田 圭吾, 小林 謙, 鈴木 貴弘, 西邑 隆徳

    日本畜産学会大会講演要旨集   125回   172 - 172   2019.3

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  • リング型僧帽弁バイオバルブの開発

    中山 泰秀, 湯浅 啓史, 寺澤 武, 田地川 勉

    日本心臓血管外科学会学術総会抄録集   49回   [OP27 - 3]   2019.2

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  • iBTA-induced Biosheet for Leaflet Material in Aortic Valve Reconstruction

    Yasuhide Nakayama, Takeshi Terazawa, Takeshi Kawashima, Keitaro Okamoto, Shinji Miyamoto

    Structural Heart   3   137 - 137   2019.1

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    DOI: 10.1080/24748706.2019.1589339

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  • In-body-tissue-engineered collagenous connective tissue tube(Biotube)as a novel esophageal and tracheal scaffold.

    奥山宏臣, 樋渡勝平, 梅田聡, 高間勇一, 寺澤武, 中山泰秀

    日本外科学会定期学術集会(Web)   119th   SY - 2   2019

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  • iBTA気管再生材の開発 パッチ修復、導管移植の検討

    中山 泰秀, 樋渡 勝平, 寺澤 武, 岩井 良輔, 梅田 聡, 高間 勇一, 奥山 宏臣

    日本獣医麻酔外科学雑誌   49 ( Suppl.2 )   222 - 222   2018.12

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  • Development of a New Aortic Valve Reconstruction Material Using In-Body Tissue Architecture Reviewed

    Takayuki Kawashima, Tadashi Umeno, Takeshi Terazawa, Keitaro Okamoto, Kyohei Hatori, Tomoyuki Wada, Takashi Shuto, Hirofumi Anai, Eisuke Tatsumi, Yasuhide Nakayama, Shinji Miyamoto

    CIRCULATION   138   2018.11

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  • バスキュラーアクセス合併症の現状と対策 バイオチューブはバスキュラーアクセスの救世主となり得るか?

    中山 泰秀, 古越 真耶, 寺澤 武, 巽 英介

    人工臓器   47 ( 2 )   S - 37   2018.10

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  • 透析治療に向けた長さ50cmの組織工学人工血管(ロングバイオチューブ)の開発

    中山 泰秀, 古越 真耶, 寺澤 武, 巽 英介

    脈管学   58 ( Suppl. )   S157 - S157   2018.9

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  • バイオシート開発の現状

    中山 泰秀, 古越 真耶, 寺澤 武, 大島 奈公子, 巽 英介

    日本獣医麻酔外科学雑誌   49 ( Suppl.1 )   271 - 271   2018.6

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  • 人工結合組織シート(バイオシート)の作製鋳型による内部構造変化

    河島 毅之, 岡本 啓太郎, 梅野 惟史, 穴井 博文, 和田 朋之, 首藤 敬史, 寺澤 武, 中山 泰秀, 巽 英介, 田北 薫子, 島田 達生, 宮本 伸二

    医学生物学電子顕微鏡技術学会誌   31 ( 1 )   42 - 42   2018.3

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  • 長い小口径バイオチューブ人工血管の開発

    中山 泰秀, 古越 真耶, 寺澤 武, 巽 英介

    日本心臓血管外科学会学術総会抄録集   48回   749 - 750   2018.2

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  • 生体内組織形成術(IBTA)による大動脈弁再建術の開発

    河島毅之, 梅野惟史, 岡本啓太郎, 和田朋之, 首藤敬史, 寺澤武, 中山泰秀, 穴井博文, 巽英介, 宮本伸二

    日本心臓血管外科学会雑誌   47 ( 4 )   xxix - xxxiii   2018

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    バイオシート作製用鋳型を成ヤギの皮下に埋植し2〜3ヵ月後に摘出して得たバイオシートから宿主大動脈弁輪の大きさに合わせてリーフレット形状に切り出したものを用いて同ヤギに対し体外循環・心停止下で大動脈弁再建術を行い、グルタルアルデヒド処理をした自己心膜を用いた場合と比較した。バイオシートの厚さと大動脈弁口通過最高血流速度(Vmax)は相関を認め、術後のVmaxは経過とともに低下傾向を認めた。移植弁の可動性はバイオシート、自己心膜ともに術後から良好であり、弁逆流はnone〜mildで推移した。術後3ヵ月時点でバイオシートは組織学的に弁輪部での完全な癒合、バイオシート内への細胞侵入など自己心膜とは異なる反応を呈した。術後6ヵ月では肉眼的にバイオシートはnative弁と酷似した形態となり、組織学的にはαSMA陽性細胞が弁尖方向に増生し、左室流出路側を中心に弾性線維による層形成を認め、さらに自己弁化していた。

    DOI: 10.4326/jjcvs.47.xxix

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  • 生体内組織形成術を用いた犬の横隔膜における新規修復材の検討

    長谷健吾, 飯盛安真, 岡本茉里, 船山麻里奈, 西田英高, 三重慧一郎, 中山泰秀, 寺澤武, 秋吉秀保

    日本産業動物獣医学会(近畿)・日本小動物獣医学会(近畿)・日本獣医公衆衛生学会(近畿)   2018   2018

  • 生体内組織形成術による再生医療 既存治療の課題解決に向けた取り組み 生体内組織形成術(IBTA)によるバイオシートを用いた大動脈弁再建術の開発

    河島 毅之, 梅野 惟史, 岡本 啓太郎, 和田 朋之, 溝口 貴之, 首藤 敬史, 寺澤 武, 中山 泰秀, 穴井 博文, 巽 英介, 宮本 伸二

    人工臓器   46 ( 2 )   S - 20   2017.8

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  • 光断層計測装置によるヒト心膜の厚みマッピングと物性評価

    寺澤 武, 尾崎 重之, 巽 英介, 中山 泰秀

    人工臓器   46 ( 2 )   S - 101   2017.8

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  • 生体内組織形成術による再生医療 既存治療の課題解決に向けた取り組み 生体内組織形成術で耳介様組織を作る

    寺澤 武, 巽 英介, 中山 泰秀

    人工臓器   46 ( 2 )   S - 21   2017.8

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  • バイオチューブのバスキュラーアクセスへの応用をめざして ビーグル犬モデルの作製と評価

    古越 真耶, 寺澤 武, 巽 英介, 中山 泰秀

    人工臓器   46 ( 2 )   S - 159   2017.8

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  • バイオシートの大動脈弁再建術への応用をめざす物性評価

    寺澤 武, 河島 毅之, 梅野 惟史, 和田 朋之, 宮本 伸二, 巽 英介, 中山 泰秀

    人工臓器   46 ( 2 )   S - 144   2017.8

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  • ウシ生体内で形成させた移植医療用組織の構造

    今山知佳, 鈴木貴弘, 小林謙, 三谷朋弘, 市居修, 小千田圭吾, 池田哲平, 寺澤武, 中山泰秀, 西邑隆徳

    日本畜産学会大会講演要旨   122nd   175 - 175   2017.3

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  • 家畜生体内で再生医療移植用組織をつくる

    西邑隆徳, 今山知佳, 鈴木貴弘, 小林謙, 三谷朋弘, 市居修, 小千田圭吾, 池田哲平, 寺澤武, 中山泰秀

    日本畜産学会大会講演要旨   122nd   175 - 175   2017.3

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  • バイオチューブ人工血管の仕様設計の多様性

    中山泰秀, 寺澤武

    日本小児循環器学会雑誌   33 ( Supplement 1 )   s1 - 175   2017

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  • 生体内組織形成術による結合組織膜(biosheet)を用いた食道再生の可能性

    梅田聡, 中山泰秀, 高間勇一, 寺澤武, 奥山宏臣

    日本小児外科学会雑誌   53 ( 3 )   728 - 728   2017

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  • 生体内組織形成術による管状組織体の壁厚制御

    45 ( 2 )   129 - 129   2016.10

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  • 生体内組織工学による再生医療の最前線 バイオシートを用いた気管形成術の有用性

    奥山 宏臣, 梅田 聡, 高間 勇一, 寺澤 武, 中山 泰秀

    人工臓器   45 ( 2 )   S - 22   2016.10

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  • 生体内組織形成術による管状組織体の壁厚制御

    寺澤 武, 西邑 隆徳, 三谷 朋弘, 市居 修, 中山 泰秀

    人工臓器   45 ( 2 )   S - 129   2016.10

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  • Development and evaluation of the lane keeping support system which considered a driver characteristic

    寺澤武, 狩谷悠史, 工藤新也, 小山哉, 藤岡健彦

    自動車技術会学術講演会前刷集   ( 4-07 )   2007

  • 1405 Driving Assistance by means of Feed-Forward control system

    Yuji KARIYA, Takehiko FUJIOKA, Hajime OYAMA, Shinya KUDOU, Takeshi TERAZAWA

    The Proceedings of the Transportation and Logistics Conference   2006.15   301 - 304   2006

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    Language:Japanese   Publishing type:Research paper, summary (national, other academic conference)   Publisher:Japan Society of Mechanical Engineers  

    File: 2006.15_301.pdf

    DOI: 10.1299/jsmetld.2006.15.301

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Presentations

  • Development of Endotracheal Liquid Perfusion Therapy with ECMO to Treat Multiple Patients with Severe Respiratory Failure in a Pandemic

    Yoshiaki Takewa,Yusuke Inoue, Takeshi Terazawa, Yasushi Sato

    APSAO 2024 Congress  2024.12 

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  • Development of TranscatheterImplantable Autologous Tissue-Engineered Artificial Heart Valve for Congenital Heart Disease

    Yasushi Sato, Takeshi Terazawa, Yusuke Inoue, Yoshiaki Takewa

    APSAO 2024 Congress  2024.12 

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  • Optimal Shape Exploration of Autologous Tissue-Engineered Artificial Heart Valve Through Structural Analysis

    Takeshi Terazawa, Yasushi Sato, Yusuke Inoue, Yoshiaki Takewa

    APSAO 2024 Congress  2024.12 

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    Event date: 2024.12

    Language:English   Presentation type:Oral presentation (general)  

    File: 5c2c6244dc79403799d9bb45290e3e90.pdf

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  • 重症肺炎に対するECMO装着下での経気道的薬剤投与による治療法の開発

    井上 雄介, 佐藤 康史, 寺澤 武, 米田 有希, 武輪 能明

    第62回日本人工臓器学会大会  2024.11 

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  • 経カテーテル的肺動脈弁置換への応用を目指した自己拡張ステント一体型自己組織生体弁の大 動物における移植評価

    佐藤 康史, 井上 雄介, 寺澤 武, 藤本 一途, 白石 公, 高松 賢介, 太田 邦博, 武輪 能明

    第62回日本人工臓器学会大会  2024.11 

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  • 生体内で形成された自己組織心臓弁グラフトの構造解析による至適形状探索

    寺澤 武, 佐藤 康史, 井上 雄介, 武輪 能明

    第62回日本人工臓器学会大会  2024.11 

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  • Development of Endotracheal Liquid Perfusion Therapy with ECMO to Treat Multiple Patients with Severe Respiratory Failure in a Pandemic

    Yoshiaki Takewa, Yusuke Inoue, Takeshi Terazawa, Yasushi Sato

    30th Annual Meeting of the ISMCS  2024.11 

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  • Development of Autologous Tissue-Engineered Artificial Heart Valve for Transcatheter Pulmonary Valve Implantation

    Yasushi Sato, Takeshi Terazawa, Yusuke Inoue, Yoshiaki Takewa

    ISACB 19th Biennial Meeting  2024.10 

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  • Development of aggressive treatment to administer drugs directly into the trachea of patients on ECMO

    Inoue Yusuke, Sato Yasushi, Terazawa Takeshi, Nagayoshi Tomoki, Takewa Yoshiaki

    50th ESAO Congress  2024.9 

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  • Application of a Two-Stage Stent for the Development of Transcatheter Autologous Tissue-Derived Pulmonary Valve Implantation

    Takewa Yoshiaki, Inoue Yusuke, Terazawa Takeshi, Sato Yasushi, Nagayoshi Tomoki, Fujimoto Kazuto, Shiraishi Isao, Takamatsu Ken, Ohta Kunio

    50th ESAO Congress  2024.9 

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  • Development of minimally invasive implantable autologous tissue-engineered heart valve for congenital heart disease

    Sato Yasushi, Inoue Yusuke, Terazawa Takeshi, Nagayoshi Tomoki, Fujimoto Kazuto, Shiraishi Isao, Takamatsu Ken, Ohta Kunio, Takewa Yoshiaki

    50th ESAO Congress  2024.9 

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  • 病理画像中の組織種分類に資するインタラクティブ機械学習ツールの開発とその評価

    酒井 昇馬, 寺澤 武, 荒川 俊也

    第40回ファジィシステムシンポジウム  2024.9 

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  • 生体内での自己組織心臓弁グラフトの形成と至適形状設計

    寺澤 武, 佐藤 康史, 井上 雄介, 永吉 智紀, 武輪 能明

    日本生物工学会 2024年度生物工学若手研究者の集い夏のセミナー2024  2024.7 

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  • ウイルス等感染症による重症肺炎に対するECMO下での経気道積極的肺治療法の開発

    佐藤 康史, 井上 雄介, 寺澤 武, 永吉 智紀, 武輪 能明

    第52回人工心臓と補助循環懇話会学術集会  2024.4 

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  • Development Of Transcatheter Implantable Autologous Tissue-engineered Artificial Heart Valve For Congenital Heart Disease

    Yasushi Sato, Takeshi Terazawa, Yusuke Inoue, Yoshiaki Takewa

    HVS2024  2024.2 

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  • カテーテル治療へ応用可能な自己組織生体弁(バイオバルブ)の開発

    永吉 智紀, 井上 雄介, 寺澤 武, 佐藤 康史, 武輪 能明

    第36回代用臓器・再生医学研究会総会 日本バイオマテリアル学会北海道ブロック第8回研究会  2024.2 

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  • ステンレス製皮下植え込みデバイスが生体の組織形成に与える影響

    佐藤 康史, 寺澤 武, 井上 雄介, 武輪 能明

    第61回日本人工臓器学会大会  2023.11 

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  • TPVIへの適応を目指した自己拡張ステント一体型自己組織生体弁の開発

    佐藤 康史, 寺澤 武, 井上 雄介, 高松 賢介, 太田 邦博, 武輪 能明

    第61回日本人工臓器学会大会  2023.11 

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  • AIを用いた数理最適化演算と流体-構造連成解析による至適心臓弁形状モデリング手法の開発 Invited

    寺澤 武, 佐藤 康史, 井上 雄介, 永吉 智紀, 山田 健人, 紀本 直, 山名 智尋, 堀江 風花, 武輪 能明

    第61回日本人工臓器学会大会  2023.11 

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  • ウイルス感染症などに起因する重症肺炎に対する ECMO装着下での経気道的治療法の開発

    井上 雄介, 佐藤 康史, 寺澤 武, 武輪 能明

    第61回日本人工臓器学会大会  2023.11 

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    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

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  • 圧電性ポリ乳酸材料の荷電性が生体内形成組織の物性に与える影響

    寺澤 武, 佐藤 康史, 井上 雄介, 永吉 智紀, 中西 修一, 辻 雅之, 山崎 洸生, 白木 秀幸, 武輪 能明

    第61回日本人工臓器学会大会  2023.11 

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  • 生体内組織形成術による組織再生能を有する自己組織由来人工心臓弁の開発

    佐藤 康史, 寺澤 武, 井上 雄介, 武輪 能明

    日本再生医療学会第3回科学シンポジウム  2023.11 

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  • 生体内で形成される組織工学心臓弁グラフトの至適形状探索

    寺澤 武, 佐藤 康史, 井上 雄介, 永吉 智紀, 武輪 能明

    日本再生医療学会第3回科学シンポジウム  2023.11 

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  • Development of Autologous Tissue-Derived Artificial Heart Valve Combined with Stent for the Transcatheter pulmonary valve implantation.

    Yasushi Sato, Takeshi Terazawa, Yusuke Inoue, Kensuke Takamatsu, Kunihiro Ota, Yoshiaki Takewa

    7th APSAO 2023 Congress  2023.9 

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    Event date: 2023.9

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  • 体内組織工学プロセスによる新しい自己組織人工心臓弁の開発

    佐藤 康史, 寺澤 武, 井上 雄介, 武輪 能明

    第75回日本生物工学会大会  2023.9 

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  • Development of an aggressive therapy to administer drugs directly into the trachea to improve survival and achieve early weaning of patients on ECMO

    Inoue Y, Sato Y, Terazawa T, Kimoto N, Yamada K, Horie F, Yamana C, Takewa Y

    49th ESAO and IFAO Congress  2023.8 

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  • Investigation of the possibility of substituting an autologous biological heart valve for various valve diseases

    Takewa Y, Inoue Y, Terazawa T, Sato Y

    49th ESAO and IFAO Congress  2023.8 

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  • 敵対的生成ネットワークによる人工病理画像が深層学習の組織検出精度に与える影響

    一宮 光悦, 寺澤 武, 荒川 俊也

    第112回日本病理学会総会  2023.4 

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  • 様々な大動脈弁疾患に対する自己組織生体弁を代用とする可能性の検討

    武輪 能明, 井上 雄介, 寺澤 武, 佐藤 康史

    第53回日本心臓血管外科学会学術集会  2023.3 

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  • 敵対的生成ネットワーク(GAN)を用いた人工病理画像生成とその評価

    一宮 光悦, 寺澤 武, 荒川 俊也

    電気学会U-21学生研究発表会  2023.3 

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  • 重症肺炎に対するECMO装着下での経気道的治療法の開発

    井上 雄介, 佐藤 康史, 寺澤 武, 紀本 直, 山田 健人, 武輪 能明

    第51回人工心臓と補助循環懇話会学術集会  2023.2 

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  • 自己組織生体弁はロス手術よりも進化した大動脈弁置換の選択肢となり得るか?

    武輪 能明, 井上 雄介, 寺澤 武, 佐藤 康史

    第60回日本人工臓器学会大会  2022.11 

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  • 生体内組織形成術によるCLOSED型心臓弁グラフト形成用鋳型の開発

    寺澤 武, 佐藤 康史, 井上 雄介, 山名 智尋, 堀江 風花, 中山 泰秀, 武輪 能明

    第60回日本人工臓器学会大会  2022.11 

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  • ECMO装着下における重症肺炎に対する経気道的治療法の開発

    井上 雄介, 佐藤 康史, 寺澤 武, 堀江 風花, 山名 智尋, 武輪 能明

    第60回日本人工臓器学会大会  2022.11 

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  • 敵対的生成ネットワーク(GAN)によるディープラーニング用人工病理画像生成の可能性

    寺澤 武, 一宮 光悦, 諏訪 陵弥, 荒川 俊也, 佐藤 康史, 井上 雄介, 武輪 能明

    第60回日本人工臓器学会大会  2022.11 

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    Language:Japanese   Presentation type:Poster presentation  

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  • 圧電性ポリ乳酸繊維を用いた移植用グラフトの開発

    佐藤 康史, 寺澤 武, 井上 雄介, 武輪 能明

    第60回日本人工臓器学会大会  2022.11 

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    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

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  • COVID-19重症肺炎に対するECMO下での経気道的治療法の開発

    佐藤 康史, 井上 雄介, 寺澤 武, 堀江 風花, 山名 智尋, 山家 智之, 白石 泰之, 山田 昭博, 武輪 能明

    第50回人工心臓と補助循環懇話会学術集会  2022.4 

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    Event date: 2022.4

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 敵対的生成ネットワーク(GAN)による病理画像生成

    一宮光悦, 諏訪陵弥, 寺澤武, 荒川俊也

    「動的システムの状態推定とデータからの学習およびその応用」研究会  2022.3 

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    Event date: 2022.3

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • GAN生成病理画像の深層学習への適用が組織検出精度に与える影響の検証

    諏訪 陵弥, 一宮 光悦, 寺澤 武, 荒川 俊也

    「動的システムの状態推定とデータからの学習およびその応用」研究会  2022.3 

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    Event date: 2022.3

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • COVID-19 肺炎重症例に対するECMO下での経気道的治療法確立への挑戦

    堀江風花, 井上雄介, 佐藤康史, 山名智尋, 寺澤武, 武輪能明

    第34回代用臓器・再生医学研究会総会 日本バイオマテリアル学会北海道ブロック第6回研究会  2022.2 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 自己組織心臓弁グラフト形成用鋳型の開発と臨床応用の可能性検証

    山名智尋, 寺澤武, 堀江風花, 佐藤康史, 井上雄介, 武輪能明

    第34回代用臓器・再生医学研究会総会 日本バイオマテリアル学会北海道ブロック第6回研究会  2022.2 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 生体内組織形成術を用いたBio-Culture-Plateの開発と性能評価

    佐藤康史, 寺澤武, 井上雄介, 武輪能明

    第34回代用臓器・再生医学研究会総会 日本バイオマテリアル学会北海道ブロック第6回研究会  2022.2 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 圧電性ポリ乳酸繊維を埋め込み材料にした医療機器の開発

    武輪 能明, 井上 雄介, 寺澤 武, 佐藤 康史

    第59回日本人工臓器学会大会  2021.11 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 生体内組織形成術を用いた微細表面構造を有する生体内組織培養基盤の作製

    佐藤 康史, 寺澤 武, 井上 雄介, 武輪 能明

    第59回日本人工臓器学会大会  2021.11 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 組織形成・再生過程を定量評価するための病理画像解析用人工知能の開発

    寺澤 武, 荒川 俊也, 佐藤 康史, 井上 雄介, 武輪 能明

    第59回日本人工臓器学会大会  2021.11 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 旭川医科大学大型慢性動物実験施設における抗血栓性ECMOの開発

    井上 雄介, 寺澤 武, 佐藤 康史, 藤原 立樹, 大内 克洋, 土方 亘, 田仲 結衣, 畠中 晃平, 横田 幸恵, 武輪 能明

    第59回日本人工臓器学会大会  2021.11 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 自己組織心臓弁グラフト(バイオバルブ)の至適心臓弁形状探索のための鋳型設計法開発

    寺澤 武, 佐藤 康史, 井上 雄介, 中山 泰秀, 武輪 能明

    第59回日本人工臓器学会大会  2021.11 

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    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

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  • 生体と医療機器の境界面で使用するハイブリッド材料の最適足場検討

    井上 雄介, 川瀬 由季乃, 田代 彩夏, 斎藤 逸郎, 磯山 隆, 山田 昭博, 山家 智之, 寺澤 武, 佐藤 康史, 武輪 能明

    第60回日本生体医工学会大会  2021.6 

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    Presentation type:Oral presentation (general)  

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  • Change of histological structure after implantation of tissue-engineered heart valve

    Yoshiaki Takewa, Yasuhide Nakayama, Yusuke Inoue, Takeshi Terazawa, Yasushi Sato

    69th ESCVS  2021.3 

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    Language:English   Presentation type:Oral presentation (general)  

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  • ディープラーニングを用いた染色画像内の毛細血管定量化手法の開発

    寺澤武, 谷川諒, 佐藤康史, 井上雄介, 荒川俊也, 武輪能明

    第33回代用臓器・再生医学研究会総会/日本バイオマテリアル学会北海道ブロック第5回研究会  2021.2 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 深層学習の医用画像診断への応用

    谷川諒, 寺澤武, 荒川俊也

    計測自動制御学会システム・情報部門学術講演会2020  2020.11 

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    Presentation type:Oral presentation (general)  

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  • 自動運転の過信・依存を抑制する操舵HMIの提案

    壁谷直樹, 寺澤武, 荒川俊也

    計測自動制御学会システム・情報部門学術講演会2020  2020.11 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 人工臓器と再生医療の融合により生まれた組織工学人工弁の開発

    武輪能明, 井上雄介, 寺澤武, 佐藤康史, 中山泰秀

    第58回日本人工臓器学会大会  2020.11  (一社)日本人工臓器学会

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    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

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  • 生体内組織形成術(iBTA)による脱細胞化牛バイオシートを用いた成ヤギ大動脈弁形成術の経験

    梅野惟史, 岡本啓太郎, 河島毅之, 和田朋之, 穴井博文, 岩井良輔, 寺澤武, 中山泰秀, 宮本伸二

    第73回日本胸部外科学会定期学術集会  2020.11 

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    Presentation type:Oral presentation (general)  

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  • iBTAを用いた大動脈弁再建術の山羊1年成績

    岡本啓太郎, 河島毅之, 梅野惟史, 和田朋之, 首藤敬史, 寺澤武, 中山泰秀, 穴井博文, 宮本伸二

    第72回日本胸部外科学会定期学術集会  2019.11 

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    Event date: 2019.10 - 2019.11

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  • 大動脈弁再建術における再生型弁膜材料としてのバイオシートの可能性

    中山 泰秀, 寺澤 武, 河島 毅之, 岡本 啓太郎, 宮本 伸二

    第55回日本小児循環器学会総会・学術集会  2019.6 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    https://confit.atlas.jp/guide/event/jspccs55/subject/II-OR26-02/advanced

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  • In-body-tissue-engineered collagenous connective tissue tube(Biotube) as a novel esophageal and tracheal scaffold

    奥山宏臣, 樋渡勝平, 梅田聡, 高間勇一, 寺澤武, 中山泰秀

    第119回日本外科学会定期学術集会  2019.4  (一社)日本外科学会

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    Language:English   Presentation type:Symposium, workshop panel (public)  

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  • 生体内組織形成術を用いて作製したウシ由来バイオシートの性状に及ぼす生体内環境の影響

    今山知佳, 寺澤武, 中山泰秀, 三谷朋弘, 市居修, 池田哲平, 小千田圭吾, 小林謙, 鈴木貴弘, 西邑隆徳

    日本畜産学会第125回大会  2019.3 

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    Language:Japanese  

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  • 細胞自己凝集化技術(CAT)の生体内組織形成術(iBTA)との融合による気管様構造体の実現

    岩井良輔, 小松大貴, 樋渡勝平, 寺澤武, 中山泰秀, 奥山宏臣

    第18回日本再生医療学会総会  2019.3 

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  • 同種および異種バイオシートの横隔膜再生材への応用

    第18回日本再生医療学会総会  2019.3 

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  • 生体内組織形成術(iBTA)を応用し生分解性ステントを内包したBIOTUBEによる気管置換

    樋渡勝平, 中山泰秀, 梅田聡, 高間勇一, 寺澤武, 奥山宏臣

    第18回日本再生医療学会総会  2019.3 

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  • Shelf-ready型の移植材をめざして生体内組織形成術(iBTA)組織の脱細胞化

    岩井良輔, 長島諒, 河島毅之, 羽鳥恭平, 首藤敬史, 寺澤武, 佐藤康史, 西邑隆徳, 中山泰秀, 宮本伸二

    第18回日本再生医療学会総会  2019.3 

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  • 世界最長組織工学人工血管の開発

    中山泰秀, 古越真耶, 寺澤武

    第18回日本再生医療学会総会  2019.3 

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  • リング型僧帽弁バイオバルブの開発

    中山 泰秀, 湯浅 啓史, 寺澤 武, 田地川 勉

    第49回日本心臓血管外科学会学術総会  2019.2 

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  • iBTA気管再生材の開発:パッチ修復,導管移植の検討

    中山泰秀, 樋渡勝平, 寺澤武, 岩井良輔, 梅田聡, 高間勇一, 奥山宏臣

    第97回日本獣医麻酔外科学会・2018年秋季合同学会  2018.1  (一社)日本獣医麻酔外科学会

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • バイオシート開発の現状

    中山泰秀, 古越真耶, 寺澤武, 大島奈公子, 巽英介

    第97回日本獣医麻酔外科学会・2018年秋季合同学会  2019.1  (一社)日本獣医麻酔外科学会

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    Language:Japanese  

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  • バイオチューブはバスキュラーアクセスの救世主となり得るか?

    第56回日本人工臓器学会大会  2018.11 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 透析治療に向けた長さ50cmの組織工学人工血管(ロングバイオチューブ)の開発

    中山 泰秀, 古越 真耶, 寺澤 武, 巽 英介

    脈管学  2018.10 

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    Language:Japanese  

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  • 生体内組織形成術を用いた犬の横隔膜における新規修復材の検討

    長谷健吾, 飯盛安真, 岡本茉里, 船山麻里奈, 西田英高, 三重慧一郎, 中山泰秀, 寺澤武, 秋吉秀保

    日本産業動物獣医学会(近畿)・日本小動物獣医学会(近畿)・日本獣医公衆衛生学会(近畿)  2018.10 

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  • Tracheal Replacement using an in-body tissue engineered collagenous tube biotube with a biodegradable stent in a beagle model: anovel tracheal scaffold.

    Shohei Hiwatashi, Yasuhide Nakayama, Yuichi Takama, Satoshi Umeda, Takeshi Terazawa, Hiroomi Okuyama

    19th European Congress of Pediatric Surgery  2018.6 

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    Language:English   Presentation type:Oral presentation (general)  

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  • Living aortic valveを目指して-生体内組織形成術(IBTA)によるバイオリーフレット開発

    The 17th Congress of the japanese Society for Regenerative Medicine  2018.3 

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    Event date: 2018.3

    Presentation type:Symposium, workshop panel (nominated)  

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  • 長い小口径バイオチューブ人工血管の開発

    中山泰秀, 古越真耶, 寺澤武, 巽英介

    第48回日本心臓血管外科学会学術総会  2018.2 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 生体内組織形成術(IBTA)による大動脈弁再建組織の開発

    河島毅之, 梅野惟史, 岡本啓太郎, 和田朋之, 溝口貴之, 首藤敬史, 寺澤武, 中山泰秀, 穴井博文, 巽英介, 宮本伸二, 山本浩史

    第48回日本心臓血管外科学会学術総会  2018.2 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • アクセス応用をめざす自家結合組織人工血管「バイオチューブ」とは?

    中山泰秀, 古越真耶, 寺澤武, 巽英介

    第21回日本アクセス研究会学術集会・総会  2017.10 

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  • 生体内組織形成術(IBTA)によるバイオシートを用いた大動脈弁再建術の開発

    河島毅之, 梅野惟史, 岡本啓太郎, 和田朋之, 溝口貴之, 首藤敬史, 寺澤武, 中山泰秀, 穴井博文, 巽英介, 宮本伸二

    第55回日本人工臓器学会大会  2017.9 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

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  • 生体内組織形成術で耳介様組織を作る

    寺澤武, 巽英介, 中山泰秀

    第55回日本人工臓器学会大会  2017.9 

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    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

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  • 光断層計測装置によるヒト心膜の厚みマッピングと物性評価

    寺澤武, 尾崎重之, 巽英介, 中山泰秀

    第55回日本人工臓器学会大会  2017.9 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • バイオチューブのバスキュラーアクセスへの応用をめざして:ビーグル犬モデルの作製と評価

    古越真耶, 寺澤武, 巽英介, 中山泰秀

    第55回日本人工臓器学会大会  2017.9 

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    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

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  • バイオシートの大動脈弁再建術への応用をめざす物性評価

    寺澤武, 河島毅之, 梅野惟史, 和田朋之, 宮本伸二, 巽英介, 中山泰秀

    第55回日本人工臓器学会大会  2017.9 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 家畜生体内で再生医療移植用組織をつくる

    西邑隆徳, 今山知佳, 鈴木貴弘, 小林謙, 三谷朋弘, 市居修, 小千田圭吾, 池田哲平, 寺澤武, 中山泰秀

    日本畜産学会第122回大会  2017.3 

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    Language:Japanese  

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  • ウシ生体内で形成させた移植医療用組織の構造

    今山知佳, 鈴木貴弘, 小林謙, 三谷朋弘, 市居修, 小千田圭吾, 池田哲平, 寺澤武, 中山泰秀, 西邑隆徳

    日本畜産学会第122回大会  2017.3 

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  • 生体内組織形成術による自己結合組織(Biosheet,Biotube)を用いた食道ならびに気管再建術の検討

    奥山宏臣, 梅田聡, 高間勇一, 寺澤武, 中山泰秀

    第16回日本再生医療学会総会  2017.3 

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    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

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  • バイオシートを用いた気管形成術の有用性

    梅田聡, 中山泰秀, 寺澤武, 高間勇一, 奥山宏臣

    第16回日本再生医療学会総会  2017.3 

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  • 生体内組織形成術による組織厚制御の可能性:管状組織体の作製

    寺澤武, 西邑隆徳, 三谷朋弘, 市居修, 中山泰秀

    第16回日本再生医療学会総会  2017.3 

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  • 生体内組織形成術による形状制御の可能性:三次元棒状組織体の作製

    寺澤武, 中山泰秀

    第16回日本再生医療学会総会  2017.3 

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  • 生体内組織形成術による管状組織体の壁厚制御

    寺澤武, 西邑隆徳, 三谷朋弘, 市居修, 中山泰秀

    第54回日本人工臓器学会大会  2016.11 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • バイオシートを用いた気管形成術の有用性

    奥山宏臣, 梅田聡, 高間勇一, 寺澤武, 中山泰秀

    第54回日本人工臓器学会大会  2016.11 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 生体内組織工学による再生医療の最前線 バイオシートを用いた気管形成術の有用性

    奥山 宏臣, 梅田 聡, 高間 勇一, 寺澤 武, 中山 泰秀

    第54回日本人工臓器学会大会  2016.11 

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    Event date: 2016.11

    Language:Japanese  

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  • 1405 Driving Assistance by means of Feed-Forward control system

    KARIYA Yuji, FUJIOKA Takehiko, OYAMA Hajime, KUDOU Shinya, TERAZAWA Takeshi

    The Proceedings of the Transportation and Logistics Conference  2006.12  The Japan Society of Mechanical Engineers

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    Event date: 2006.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Driver steering is affected by various inputs, but driver's actions can be classified broadly into three types: trajectory planning, steering by means of feed-forward control, and steering by means of feedback control Current assist systems demonstrated by lane-keep control systems are mainly driver assistance by means of feedback control. Instead, we tried to construct a driving assistance system by means of feed-forward control. This system has advantages of being simpler than the other systems and enabling drives to override. Research was conducterd using a driving simulator and performed an evaluation of the system by measuring steering torque during driving several simulated courses.

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  • Development and evaluation of the lane keeping support system which considered a driver characteristic

    寺澤武, 狩谷悠史, 工藤新也, 小山哉, 藤岡健彦

    自動車技術会2007年春季学術講演会  2007.5 

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  • 病理画像生成における敵対的生成ネットワーク(GAN)の適用

    一宮 光悦, 諏訪 陵弥, 寺澤 武, 荒川 俊也

    生物工学若手研究者の集い 夏のオンラインセミナー2022  2022.5 

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  • GAN生成病理画像が深層学習を用いた組織検出精度に与える影響

    諏訪 陵弥, 一宮 光悦, 寺澤 武, 荒川 俊也

    生物工学若手研究者の集い 夏のオンラインセミナー2022  2022.5 

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Industrial property rights

  • ステントグラフト形成基材

    武輪 能明, 寺澤 武, 井上 雄介, 佐藤 康史, 中山 泰秀

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    Applicant:国立大学法人旭川医科大学, バイオチューブ株式会社

    Application no:特願2023-046431  Date applied:2023.3

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  • 弁付きグラフト形成基材

    寺澤 武, 武輪 能明, 井上 雄介, 佐藤 康史, 中山 泰秀

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    Applicant:国立大学法人旭川医科大学, バイオチューブ株式会社

    Application no:特願2022-040595  Date applied:2022.3

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  • 結合組織体及びその製造方法

    中山泰秀, 佐藤康史, 寺澤武

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    Application no:特願2019-128790  Date applied:2019.7

    Announcement no:特開2021-013480  Date announced:2021.2

    Patent/Registration no:特許6755052  Date registered:2020.8 

    Country of applicant:Domestic  

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  • 管状補強体及び管状人工臓器

    福瀧 修司, 井手 純一, 山本 彩佳, 中山 泰秀, 寺澤 武, 奥山 宏臣, 高間 勇一, 樋渡 勝平

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    Applicant:ジェイ・エム・エス, 国立研究開発法人国立循環器病研究センター, 国立大学法人大阪大学

    Application no:特願2019-014816  Date applied:2019.1

    Announcement no:特開2020-120944  Date announced:2020.8

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  • ステアリング装置

    寺澤 武

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    Applicant:株式会社SUBARU

    Application no:特願2017-209626  Date applied:2017.10

    Announcement no:特開2018-047896  Date announced:2018.3

    Patent/Registration no:特許6387172  Date registered:2018.8 

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  • 車両の操舵支援装置

    青山 裕紀, 寺澤 武

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    Applicant:株式会社SUBARU

    Application no:特願2016-062073  Date applied:2016.3

    Announcement no:特開2017-171224  Date announced:2017.9

    Patent/Registration no:特許6663767  Date registered:2020.2 

    Rights holder:株式会社SUBARU

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  • 車両の運転支援制御装置

    寺澤 武

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    Applicant:株式会社SUBARU

    Application no:特願2015-248867  Date applied:2015.12

    Announcement no:特開2017-114168  Date announced:2017.6

    Patent/Registration no:特許6661214  Date registered:2020.2 

    Rights holder:株式会社SUBARU

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  • 車両の運転支援制御装置

    寺澤 武

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    Applicant:株式会社SUBARU

    Application no:特願2015-244379  Date applied:2015.12

    Announcement no:特開2017-109560  Date announced:2017.6

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  • 車両の運転支援制御装置

    寺澤 武

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    Applicant:株式会社SUBARU

    Application no:特願2015-238720  Date applied:2015.12

    Announcement no:特開2017-105249  Date announced:2017.6

    Patent/Registration no:特許6661213  Date registered:2020.2 

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  • 車両の操舵パラメータ推定装置

    寺澤 武, 青山 裕紀

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    Applicant:富士重工業株式会社

    Application no:特願2015-220915  Date applied:2015.11

    Announcement no:特開2017-087983  Date announced:2017.5

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  • 車両の車線逸脱防止制御装置

    羽鹿 亮, 寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2015-058147  Date applied:2015.3

    Announcement no:特開2016-175570  Date announced:2016.10

    Patent/Registration no:特許6535490  Date registered:2019.6 

    Rights holder:株式会社SUBARU

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  • 車両の車線逸脱防止制御装置

    羽鹿 亮, 寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2015-058148  Date applied:2015.3

    Announcement no:特開2016-175571  Date announced:2016.10

    Patent/Registration no:特許6541216  Date registered:2019.6 

    Rights holder:株式会社SUBARU

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  • 車両の車線逸脱防止制御装置

    寺澤 武, 若杉 恒宏

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    Applicant:富士重工業株式会社

    Application no:特願2015-055149  Date applied:2015.3

    Announcement no:特開2016-175446  Date announced:2016.10

    Patent/Registration no:特許6497806  Date registered:2019.3 

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  • 車両運動パラメータ推定装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2014-263141  Date applied:2014.12

    Announcement no:特開2016-120882  Date announced:2016.7

    Patent/Registration no:特許6478318  Date registered:2019.2 

    Rights holder:株式会社SUBARU

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  • 車両の車線逸脱防止制御装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2014-189288  Date applied:2014.9

    Announcement no:特開2016-060349  Date announced:2016.4

    Patent/Registration no:特許第5947849号  Date issued:2016.6

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  • 車両の車線逸脱防止制御装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2014-073027  Date applied:2014.3

    Announcement no:特開2015-194946  Date announced:2015.11

    Patent/Registration no:特許第5936281号  Date issued:2016.5

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  • 車両の車線逸脱防止制御装置

    寺澤 武, 玉置 健

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    Applicant:富士重工業株式会社

    Application no:特願2014-069710  Date applied:2014.3

    Patent/Registration no:特許第5798658号  Date issued:2015.8

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  • 車両の車線逸脱防止制御装置

    寺澤 武

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    Applicant:株式会社SUBARU

    Application no:特願2014-069708  Date applied:2014.3

    Announcement no:特開2015-189410  Date announced:2015.11

    Patent/Registration no:特許第6327701号  Date issued:2018.4

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  • 車両の車線逸脱防止制御装置

    寺澤 武

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    Applicant:株式会社SUBARU

    Application no:特願2014-069707  Date applied:2014.3

    Announcement no:特開2015-189409  Date announced:2015.11

    Patent/Registration no:特許第6317972号  Date issued:2018.4

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  • 計測装置、及びそれを用いた故障診断装置

    寺澤 武

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    Applicant:株式会社SUBARU

    Application no:特願2014-069709  Date applied:2014.3

    Announcement no:特開2015-190920  Date announced:2015.11

    Patent/Registration no:特許第6322023号  Date issued:2018.4

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  • 車両の車線逸脱防止制御装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2014-066640  Date applied:2014.3

    Announcement no:特開2015-191316  Date announced:2015.11

    Patent/Registration no:特許6338417  Date registered:2018.5 

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  • 操舵制御装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2013-080558  Date applied:2013.4

    Announcement no:特開2014-201258  Date announced:2014.10

    Patent/Registration no:特許第6106012号  Date issued:2017.3

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  • 車線逸脱防止制御装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2013-006963  Date applied:2013.1

    Announcement no:特開2013-091494  Date announced:2013.5

    Patent/Registration no:特許第5572231号  Date issued:2014.7

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  • 車線逸脱防止制御装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2013-006962  Date applied:2013.1

    Announcement no:特開2013-139257  Date announced:2013.7

    Patent/Registration no:特許第5451911号  Date issued:2014.1

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  • 操舵支援装置

    寺澤 武, 小山 哉, 工藤 新也

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    Applicant:富士重工業株式会社

    Application no:特願2013-003268  Date applied:2013.1

    Announcement no:特開2013-063778  Date announced:2013.4

    Patent/Registration no:特許第5544435号  Date issued:2014.5

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  • 4輪駆動車の制御装置

    松野 浩二, 江副 志郎, 小山 哉, 田村 悠一郎, 寺澤 武, 渡邉 明博

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    Applicant:富士重工業株式会社

    Application no:特願2012-208612  Date applied:2012.9

    Announcement no:特開2014-061815  Date announced:2014.4

    Patent/Registration no:特許第5483770号  Date issued:2014.2

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  • 車両の操舵支援装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2012-166120  Date applied:2012.7

    Announcement no:特開2014-024448  Date announced:2014.2

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  • サーボ制御装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2010-159942  Date applied:2010.7

    Announcement no:特開2012-020652  Date announced:2012.2

    Patent/Registration no:特許第5525357号  Date issued:2014.4

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  • 車両の操舵支援制御装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2009-207342  Date applied:2009.9

    Announcement no:特開2011-057037  Date announced:2011.3

    Patent/Registration no:特許第5379614号  Date issued:2013.10

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  • 車両の操舵支援制御装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2009-200569  Date applied:2009.8

    Announcement no:特開2011-051420  Date announced:2011.3

    Patent/Registration no:特許第5314539号  Date issued:2013.7

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  • 操舵支援装置

    工藤 新也, 小山 哉, 寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2008-271988  Date applied:2008.10

    Announcement no:特開2010-102435  Date announced:2010.5

    Patent/Registration no:特許第5342208号  Date issued:2013.8

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  • 操舵支援装置

    工藤 新也, 小山 哉, 寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2008-271989  Date applied:2008.10

    Announcement no:特開2010-102436  Date announced:2010.5

    Patent/Registration no:特許第5255988号  Date issued:2013.4

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  • 車線逸脱防止装置

    工藤 新也, 小山 哉, 寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2008-271987  Date applied:2008.10

    Announcement no:特開2010-100120  Date announced:2010.5

    Patent/Registration no:特許第5398222号  Date issued:2013.11

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  • 車両逸脱防止装置

    小山 哉, 工藤 新也, 寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2008-245681  Date applied:2008.9

    Announcement no:特開2010-076539  Date announced:2010.4

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  • 操舵支援装置

    寺澤 武, 小山 哉, 工藤 新也

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    Applicant:富士重工業株式会社

    Application no:特願2008-236273  Date applied:2008.9

    Announcement no:特開2010-069907  Date announced:2010.4

    Patent/Registration no:特許第5203865号  Date issued:2013.2

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  • 操舵支援装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2008-227062  Date applied:2008.9

    Announcement no:特開2010-058690  Date announced:2010.3

    Patent/Registration no:特許第5386132号  Date issued:2013.10

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  • 操向支援装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2008-227068  Date applied:2008.9

    Announcement no:特開2010-058691  Date announced:2010.3

    Patent/Registration no:特許第5185743号  Date issued:2013.1

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  • 車線逸脱防止制御装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2008-199516  Date applied:2008.8

    Announcement no:特開2010-036645  Date announced:2010.2

    Patent/Registration no:特許第5213576号  Date issued:2013.3

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  • 車線逸脱防止装置

    寺澤 武, 小山 哉, 工藤 新也

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    Applicant:富士重工業株式会社

    Application no:特願2008-185839  Date applied:2008.7

    Announcement no:特開2010-023605  Date announced:2010.2

    Patent/Registration no:特許第5254688号  Date issued:2013.4

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  • 車線逸脱防止装置

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2008-185840  Date applied:2008.7

    Announcement no:特開2010-023606  Date announced:2010.2

    Patent/Registration no:特許第5416372号  Date issued:2013.11

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  • 操舵輪舵角制御における補償値取得方法および操舵輪舵角制御における補償方法

    寺澤 武

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    Applicant:富士重工業株式会社

    Application no:特願2008-146366  Date applied:2008.6

    Announcement no:特開2009-292233  Date announced:2009.12

    Patent/Registration no:特許第5143633号  Date issued:2012.11

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  • 車線追従制御装置および車線追従制御方法

    寺澤 武, 工藤 新也

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    Applicant:富士重工業株式会社

    Application no:特願2008-002235  Date applied:2008.1

    Announcement no:特開2009-161100  Date announced:2009.7

    Patent/Registration no:特許第5389360号  Date issued:2013.10

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  • 分別装置

    寺澤 武, 金子 法正, 高桑 晋, 中里 弘海

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    Applicant:富士重工業株式会社

    Application no:特願2006-275471  Date applied:2006.10

    Announcement no:特開2008-093520  Date announced:2008.4

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Awards

  • HLGC Catalyst Award

    2024.10   National Academy of Medicine   Development of Novel Heart Valve Therapy Using Autologous Tissue-Engineered Artificial Heart Valve

    Yasushi Sato,PhD, Yoshiaki Takewa,MD,PhD, Yusuke Inoue,PhD, Takeshi Terazawa,PhD

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  • 2023年度電気学会U-21学生研究発表会 優秀賞

    2023.3   電気学会 電力・エネルギー部門   敵対的⽣成ネットワーク(GAN)を⽤いた⼈⼯病理画像⽣成とその評価

    一宮 光悦(指導教員:寺澤 武,荒川 俊也)

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

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  • Grant-MERA

    2021.11   JAPANESE SOCIETY FOR ARTIFICIAL ORGANS  

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

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  • HLGC Catalyst Award

    2021.10   National Academy of Medicine   Development of in-body tissue-engineered autologous vascular grafts (Biotube)

    Miyamoto Shinji, PhD, Nakayama Yasuhide, PhD, Yambe Tomoyuki, PhD, Tajikawa Tsutomu, PhD, Iwai Ryosuke, PhD, Takeshi Terazawa, PhD

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Research Projects

  • Research on the development of growing autologous tissue-derived transcatheter heart valves

    Grant number:23K24391  2024.4 - 2026.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

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    Grant amount:\9,100,000 ( Direct Cost: \7,000,000 、 Indirect Cost:\2,100,000 )

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  • 体内で成長する小児用人工心臓弁に関する研究

    2023.12 - 2025.1

    公益財団法人鈴木謙三記念医科学応用研究財団  調査研究の助成 助成課題1 より豊かな生活に貢献する医療技術に関する研究 

    寺澤 武, 武輪 能明, 井上 雄介, 佐藤 康史

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    Authorship:Principal investigator 

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  • 圧電性材料の医療機器への応用に関する研究

    2022.10 - 2023.9

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  • Development of autologous transcatheter heart valves with growth potential

    Grant number:22H03132  2022.4 - 2026.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

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    Grant amount:\17,030,000 ( Direct Cost: \13,100,000 、 Indirect Cost:\3,930,000 )

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  • 生体内組織形成術による自己組織心臓弁グラフトの開発

    2022.4 - 2023.3

    日本医療研究開発(AMED)  令和4年度「橋渡し研究戦略的推進プログラム(シーズA)」 

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    Authorship:Coinvestigator(s) 

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  • 成長する自家組織由来経カテーテル心臓弁の開発研究

    Grant number:22516725  2022.4

    文部科学省  科学研究費助成事業 

    武輪能明, 井上雄介, 寺澤武, 佐藤康史

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  • 圧電性ポリ乳酸繊維の医用材料への応用に必要な生体内組織形成加速及び移植後の自己組織化促進のための至適条件検討

    2021.10 - 2022.9

    公益財団法人村田学術振興財団  第37 回(2021 年度) 公益財団法人村田学術振興財団研究助成  研究助成

    寺澤 武, 武輪 能明, 井上 雄介, 佐藤 康史

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    Authorship:Principal investigator  Grant type:Competitive

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  • COVID-19の感染スクリーニングが可能となる反射型 フレキシブルパルスオキシオメータの開発

    2021.10

    伊藤医薬学術交流財団  第27回 2021(令和3)年度 招へい助成金 

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  • 深層学習による病理画像の高精細セグメンテーション技術の開発

    2021.4 - 2022.3

    公益財団法人 北海道科学技術総合振興センター ノーステック財団  2021年度【第28回】研究開発助成事業 若手研究人材育成事業 若手研究人材・ネットワーク育成補助金(ノースタレント補助金)  若手研究人材・ネットワーク育成補助金

    寺澤 武

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  • 生体内組織形成術による自家組織由来心臓弁グラフトの開発

    2021.4 - 2022.3

    日本医療研究開発機構(AMED)  令和3年度AMED「橋渡し研究戦略的推進プログラム」  シーズA

    武輪能明, 寺澤武, 井上雄介, 佐藤康史

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  • 自己組織でできたステント付き心臓弁グラフトに関する研究

    2021.4 - 2022.3

    公益財団法人秋山記念生命科学振興財団  2021年度研究助成  一般

    寺澤 武, 武輪 能明, 井上 雄介, 佐藤 康史

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  • AIを用いた数理最適化演算と流体-構造連成解析による至適心臓弁形状モデリング手法の開発

    2021.4 - 2022.3

    日本人工臓器学会  Grant-MERA賞 

    寺澤 武, 佐藤 康史

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  • 超長寿命つけ爪型パルスオキシメータの開発

    2021.4 - 2022.3

    公益財団法人 北海道科学技術総合振興センター ノーステック財団  2021年度【第28回】研究開発助成事業 イノベーション創出研究支援事業 スタートアップ研究(産学連携創出)補助金 

    井上 雄介, 都鳥 真也, 河合 良太, 磯田 浩一, 藤田 裕明, 三田村 好矩, 高塚 伸太郎, 武輪 能明, 寺澤 武, 佐藤 康史

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    Authorship:Coinvestigator(s)  Grant type:Competitive

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  • 生体内で形成された大動脈弁移植用組織体の計算流体力学的手法による形状最適化

    Grant number:20K20174  2020.4 - 2024.3

    日本学術振興会  科学研究費助成事業  若手研究

    寺澤 武

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    Grant amount:\4,160,000 ( Direct Cost: \3,200,000 、 Indirect Cost:\960,000 )

    当該年度において、以下の成果を得た。
    1) 流体構造計算を実現するための生体内形成組織の材料特性モデル化:引張試験により生体皮下形成組織体の応力-ひずみ特性を調べ構造計算用の機械的特性値とした。
    2) 弁形状のコンピュータ上での構築および組織形成用鋳型の開発:弁形状は心臓弁形状を代表する設計パラメータを次の弁輪径・弁長・交連部高・弁葉角・弁厚の5パラメータとした3次元形状とした。自己組織弁の生体皮下形成用の鋳型を、形成時の弁の状態が開放状態(Open弁)・および閉鎖状態(Closed弁)の二仕様について、設計および三次元CADにおけるモデリング・3Dプリンタによる造形を行った。Open弁の鋳型をヤギの皮下に埋込および3か月で摘出を行い自己組織弁形成を認めた。Open弁の模擬循環回路によるin vitroにおける血行動態評価を実施、既存生体弁に対して逆流率は劣るが、圧較差特性に優れることを示した。またヤギの肺動脈弁位への移植急性実験を行い、心エコー評価およびアンギオ評価により弁として機能することを明らかにした。逆流率改善を目的としたClosed弁の設計改良を進めた。鋳型の交連部および組織形成促進のために鋳型に設けられる細胞誘導孔の位置を改修し、組織形成実験につなげた。大動物による組織形成実験では、Closed弁の弁膜部は設計よりも薄いものの組織形成可能であることを示した。
    3)・4) 移植強度と弁機能を兼ね備える移植体弁尖形状の最適化:Closed弁での弁形状最適化を図るため、鋳型に対応して形成された組織体の3次元モデルを作製した。また弁の評価指標である、圧較差・逆流率を計算できるよう準備を進め、心臓弁様組織体の評価基盤を確立した。

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  • 下肢動脈バイパス用人工血管(バイオチューブ)作製用鋳型の開発

    Grant number:20316432  2020.4 - 2022.3

    日本医療研究開発機構(AMED)  橋渡し研究戦略的推進プログラム2021年度  シーズB

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  • Structual Optimization of Heart Valve Graft formed in-body tissue architecture by structure-Fluid Interaction Analysis

    2020.4 - 2020.9

    Toukai Foundation for Technology 

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  • Tomorrow's Vascular Surgery Induced by World's Longest Tissue-engineered Vascular Grafts

    Grant number:19H04447  2019.4 - 2022.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)  Grant-in-Aid for Scientific Research (B)

    Nakayama Yasuhide

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    Grant amount:\17,160,000 ( Direct Cost: \13,200,000 、 Indirect Cost:\3,960,000 )

    There are no small-diameter, long artificial vascular grafts that can be used for below-knee bypass surgery. We have developed tissue-engineered vascular grafts called Biotube using a completely autologous approach called in-body tissue architecture (iBTA). Molds were subcutaneously embedded into goats for predetermined periods (one, two, or three months). All Makers produced Biotubes as designed in all periods. All Biotubes obtained had an inner diameter of 4 mm and a length over 50 cm with wall thickness of 0.6 mm. All Biotubes did not kink when completely bent and did not leak without any deformation under a water pressure of 200 mmHg. Their burst strength was ca. 2500 mmHg. This study confirmed that Biotubes have properties comparable to arteries; hence, we will start an investigator-initiated clinical trial in near future after obtaining the results of another implantation study.

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  • 下肢動脈バイパス用人工血管作製用の鋳型の仕様決定と事業計画策定

    2019.4 - 2020.3

    国立研究開発法人日本医療研究開発機構  医工連携事業化推進事業 

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  • 生体内で形成された自己組織グラフト材料の機械的特性の解明

    2016.4 - 2018.3

    その他の試験研究機関 

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Teaching Experience

  • 医学研究特論

    2021.10 Institution:旭川医科大学

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  • Mechanism

    2019.10 - 2020.9 Institution:AICHI UNIVERSITY OF TECHNOLOGY

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  • Fundamentals of Machine Design

    2019.10 - 2020.3 Institution:AICHI UNIVERSITY OF TECHNOLOGY

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  • Engineering Seminar

    2019.10 - 2020.3 Institution:AICHI UNIVERSITY OF TECHNOLOGY

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  • Calculus

    2019.10 - 2020.3 Institution:AICHI UNIVERSITY OF TECHNOLOGY

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  • Project Experiment

    2019.4 - 2020.9 Institution:AICHI UNIVERSITY OF TECHNOLOGY

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  • Study and Carrier Build-up

    2019.4 - 2020.9 Institution:AICHI UNIVERSITY OF TECHNOLOGY

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  • Computer Aided Design/ Somputer Aided Manufacturing/ Computer Aided Engineering

    2019.4 - 2020.9 Institution:AICHI UNIVERSITY OF TECHNOLOGY

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  • Mechanical System Design

    2019.4 - 2020.3 Institution:AICHI UNIVERSITY OF TECHNOLOGY

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  • Mechanical System Engineering : Exercise

    2019.3 - 2020.9 Institution:AICHI UNIVERSITY OF TECHNOLOGY

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Social Activities

  • わくわくサイエンス in 科学館

    Role(s): Demonstrator

    旭川ウェルビーイング・コンソーシアム  2024.6

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    Type:Other

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  • わくわくサイエンス アサヒカワ ノ カガク

    Role(s): Demonstrator

    旭川ウェルビーイング・コンソーシアム  2024.2

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    Type:Other

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  • 北見工業大学R5年度医工連携ワークショップ

    Role(s): Advisor

    北見工業大学  2024.1

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    Type:Seminar, workshop

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  • 旭川西高校 体験実習

    Role(s): Lecturer

    2024.1

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  • SSH研修「旭川医科大・旭川西高校訪問」研究紹介

    Role(s): Lecturer

    北海道北見北斗高等学校  2023.9

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    Type:Seminar, workshop

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  • わくわくサイエンス~やさしい科学~

    Role(s): Demonstrator

    旭川ウェルビーイング・コンソーシアム  2023.6

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    Type:Other

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  • わくわくサイエンス アサヒカワ ノ カガク

    Role(s): Demonstrator

    旭川ウェルビーイング・コンソーシアム  2023.2

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    Type:Other

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  • わくわくサイエンス 人体のふしぎ展

    Role(s): Demonstrator

    旭川ウェルビーイング・コンソーシアム  2022.6

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    Type:Other

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  • 自分のからだで移植用心臓弁をつくる

    Role(s): Lecturer

    旭川医科大学先進医工学研究センター主催  医療の最先端講座  2022.2

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    Audience: Schoolchildren, Junior students, High school students

    Type:Seminar, workshop

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