1 - 30 of about 30
English: 1. Sumida K, Doi T, Obayashi K, Chiba Y, Nagasaka S, Ogino N, Miyagawa K, Baba R, Morimoto H, Hara H, Terabayashi T, Ishizaki T, Harada M, Endo M., Caspase-4 has a role in cell division in epithelial cells through actin depolymerization , Biochemical and Biophysical Research Communications , 2024
English: Matsuda Y, Yamauchi H, Hara H, Activation of inflammasomes and mechanisms for intracellular recognition of Listeria monocytogenes , Microbiology and Immunology , 2023
English: 1. Tanishita Y, Sekiya H, Inohara N, Tsuchiya K, Mitsuyama M, Núñez G, Hara H, Listeria Toxin Promotes Phosphorylation of the Inflammasome Adaptor ASC through Lyn and Syk to Exacerbate Pathogen Expansion , Cell Reports , 2022
English: 2. Tsuchiya K, Hosojima S, Hara H, Kushiyama H, Mahib M. R., Kinoshita T, Suda T, Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes , Cell Reports , 2021
English: 3. Fang R, Uchiyama R, Sakai S, Hara H, Tsutsui H, Suda T, Mitsuyama M, Kawamura I, Tsuchiya K, ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism , Mucosal Immunology , 2019
English: Hara H, Seregin SS, Yang D, Fukase K, Chamaillard M, Alnemri ES, Inohara N, Chen GY, Núñez G, The NLRP6 inflammasome recognizes lipoteichoic acid and regulates Gram-positive pathogen infection , Cell , 2018
English: 6. Conos SA, Chen KW, De Nardo D, Hara H, Whitehead L, Núñez G, Masters SL, Murphy JM, Schroder K, Vaux DL, Lawlor KE, Lindqvist LM, Vince JE, Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner , Proc. Natl. Acad. Sci. U S A. , 2017
English: 5. Sakamoto K, Kim YG, Hara H, Kamada N, Caballero-Flores G, Tolosano E, Soares MP, Puente JL, Inohara N, Núñez G, IL-22 controls heme/Iron-dependent nutritional immunity against systemic bacterial infections , Science Immunology , 2017
English: He Y, Hara H, Núñez G., Mechanism and Regulation of NLRP3 Inflammasome Activation , Trends in Biochemical Sciences , 2016
English: 7. Hashino M, Tachibana M, Nishida T, Hara H, Tsuchiya K, Mitsuyama M, Watanabe K, Shimizu T,Watarai M., Inactivation of the MAPK signaling pathway by Listeria monocytogenes infection promotes trophoblast giant cell death. , Front. Microbiol , 2015
English: 8. Tsuchiya K, Hara H, Fang R, Hernandez-Cuellar E, Sakai S, Daim S, Chen X, Dewamitta SR, Qu H, Mitsuyama M, Kawamura, The adaptor ASC exacerbates lethal Listeria monocytogenes infection by mediating IL-18 production in an inflammasome-dependent and -independent manner. , Eur. J. Immunol. , 2014
English: Yang R, Xi C, Sita DR, Sakai S, Tsuchiya K, Hara H, Shen Y, Qu H, Fang R, Mitsuyama M, Kawamura I. , The RD1 locus in the Mycobacterium tuberculosis genome contributes to the maturation and secretion of IL-1α from infected macrophages through the elevation of cytoplasmic calcium levels and calpain activation , Pathog. Dis. , 2014
English: Fang R, Hara H, Sakai S, Hernandez-Cuellar E, Mitsuyama M, Kawamura I, Tsuchiya K., Type I interferon signaling regulates activation of the absent in melanoma 2 inflammasome during Streptococcus pneumoniae infection , Infect. Immun. , 2014
English: Tsuchiya K and Hara H, The inflammasome and its regulation , Critical Reviews in Immunology , 2014
English: 11. Hara H, Tsuchiya K, Kawamura I, Fang R, Hernandez-Cuellar E, Shen Y, Mizuguchi J, Schweighoffer E, Tybulewicz V, Mitsuyama M, Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity , Nature Immunology , 2013
English: Hernandez-Cuellar E, Tsuchiya K, Hara H, Fang R, Sakai S, Kawamura I, Akira S, Mitsuyama M, Nitric oxide inhibits the NLRP3 inflammasome. , J. Immunol. , 2012
English: Sugata K, Satou Y, Yasunaga J, Hara H, Ohshima K, Utsunomiya A, Mitsuyama M, Matsuoka M. , HTLV-1 bZIP factor impairs cell-mediated immunity by suppressing production of Th1 cytokines. , Blood. , 2012
English: Yamamoto T, Hara H, Tsuchiya K, Sakai S, Fang R, Matsuura M, Nomura T, Sato F, Mitsuyama M, Kawamura I. , Listeria monocytogenes strain-specific impairment of the TetR regulator underlies the drastic increase in cyclic di-AMP secretion and beta interferon-inducing ability , Infect. Immun , 2012
English: Tanaka T, Takahashi K, Yamane M, Tomida S, Nakamura S, Oshima K, Niwa A, Nishikomori R, Kambe N, Hara H, Mitsuyama M, Morone N, Heuser JE, Yamamoto T, Watanabe A, Sato-Otsubo A, Ogawa S, Asaka I, Heike T, Yamanaka S, Nakahata T, Saito MK., Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery. , Blood , 2012
English: Fang R, Tsuchiya K, Kawamura I, Shen Y, Hara H, Sakai S, Yamamoto T, Fernandes-Alnemri T, Yang R, Hernandez-Cuellar E, Dewamitta SR, Xu Y, Qu H, Alnemri ES, Mitsuyama M., Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection. , J. Immunol. , 2011
English: Nagahama M, Itohayashi Y, Hara H, Higashihara M, Fukatani Y, Takagishi T, Oda M, Kobayashi K, Nakagawa I, Sakurai J., Cellular vacuolation induced by Clostridium perfringens epsilon-toxin. , FEBS J. , 2011
English: Daim S, Kawamura I, Tsuchiya K, Hara H, Kurenuma T, Shen Y, Dewamitta SR, Sakai S, Nomura T,Qu H, Mitsuyama M. , Expression of the Mycobacterium tuberculosis PPE37 protein in Mycobacterium smegmatis induces low tumour necrosis factor alpha and interleukin 6 production in murine macrophages. , J. Med. Microbiol. , 2011
English: Tsuchiya K, Hara H, Kawamura I, Nomura T, Yamamoto T, Daim S, Dewamitta SR, Shen Y, Fang R, Mitsuyama M., Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes. , J. Immunol. , 2010
English: Dewamitta SR, Nomura T, Kawamura I, Hara H, Tsuchiya K, Kurenuma T, Shen Y, Daim S,Yamamoto T, Qu H, Sakai S, Xu Y, Mitsuyama M., Listeriolysin O-dependent bacterial entry into the cytoplasm is required for calpain activation and interleukin-1 alpha secretion in macrophages infected with Listeria monocytogenes. , Infect. Immun. , 2010
English: Shen Y, Kawamura I, Nomura T, Tsuchiya K, Hara H, Dewamitta SR, Sakai S, Qu H, Daim S,Yamamoto T, Mitsuyama M. , Toll-like receptor 2- and MyD88-dependent phosphatidylinositol 3-kinase and Rac1 activation facilitates the phagocytosis of Listeria monocytogenes by murine macrophages. , Infect. Immun. , 2010
English: Kurenuma T, Kawamura I, Hara H, Uchiyama R, Daim S, Dewamitta SR, Sakai S, Tsuchiya K,Nomura T, Mitsuyama M., The RD1 locus in the Mycobacterium tuberculosis genome contributes to activation of caspase-1 via induction of potassium ion efflux in infected macrophages. , Infect. Immun. , 2009
English: Hara H, Tsuchiya K, Nomura T, Kawamura I, Shoma S, Mitsuyama M, Dependency of caspase-1 activation induced in macrophages by Listeria monocytogenes on cytolysin, listeriolysin O, after evasion from phagosome into the cytoplasm. , J. Immunol. , 2008
English: Shoma S, Tsuchiya K, Kawamura I, Nomura T, Hara H, Uchiyama R, Daim S, Mitsuyama M, Critical involvement of pneumolysin in production of interleukin-1alpha and caspase-1-dependent cytokines in infection with Streptococcus pneumoniae in vitro: a novel function of pneumolysin in caspase-1 activation. , Infect. Immun. , 2008
English: Hara H, Kawamura I, Nomura T, Tominaga T, Tsuchiya K, Mitsuyama M, Cytolysin-dependent escape of the bacterium from the phagosome is required but not sufficient for induction of the Th1 immune response against Listeria monocytogenes infection: distinct role of Listeriolysin O determined by cytolysin gene replacement. , Infect. Immun. , 2007
English: Nagahama M, Hara H, Fernandez-Miyakawa M, Itohayashi Y, Sakurai J. , Oligomerization of Clostridium perfringens epsilon-toxin is dependent upon membrane fluidity in liposomes. , Biochemistry. , 2006
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